3BH6
 
 | | Crystal structure of the RP2-Arl3 complex bound to GppNHp | | 分子名称: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Veltel, S, Gasper, R, Wittinghofer, A. | | 登録日 | 2007-11-28 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
Nat.Struct.Mol.Biol., 15, 2008
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3ZKM
 | | BACE2 FAB COMPLEX | | 分子名称: | BETA-SECRETASE 2, DIMETHYL SULFOXIDE, FAB HEAVY CHAIN, ... | | 著者 | Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. | | 登録日 | 2013-01-23 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones
Acta Crystallogr.,Sect.D, 69, 2013
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6ZHY
 | | Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: hexasome class. | | 分子名称: | Chromodomain-helicase-DNA-binding protein 1-like, DNA (110-MER) Widom 601 sequence, Histone H2A type 1, ... | | 著者 | Bacic, L, Gaullier, G, Deindl, S. | | 登録日 | 2020-06-24 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
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3BJT
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6ZJZ
 | | Discovery of M5049: a novel selective TLR7/8 inhibitor for treatment of autoimmunity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile, FORMIC ACID, ... | | 著者 | Musil, D, Lehman, M, Strauss, J. | | 登録日 | 2020-06-29 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | | 主引用文献 | Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity.
J.Pharmacol.Exp.Ther., 376, 2021
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3BGI
 | | Thiopurine S-Methyltransferase | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, Thiopurine S-methyltransferase | | 著者 | Peng, Y, Yee, V.C. | | 登録日 | 2007-11-26 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis of Substrate Recognition in Thiopurine S-Methyltransferase
Biochemistry, 47 (23), 6216 6225, 2008. 10.1021/bi800102x, 2008
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6ZEG
 | | Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580) | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE, MANGANESE (II) ION, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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3BBV
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5WK2
 | | CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, M116 HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2017-07-24 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into chemokine CCL17 recognition by antibody M116.
Biochem Biophys Rep, 13, 2018
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6ZK6
 | | Protein Phosphatase 1 (PP1) T320E mutant | | 分子名称: | FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Salvi, F, Barabas, O, Koehn, M. | | 登録日 | 2020-06-29 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.
Chembiochem, 22, 2021
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5TKL
 | | Crystal structure of FBP aldolase from Toxoplasma gondii, condensation intermediate | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ... | | 著者 | Heron, P.W, Sygusch, J. | | 登録日 | 2016-10-06 | | 公開日 | 2017-10-04 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
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3BH4
 | | High resolution crystal structure of Bacillus amyloliquefaciens alpha-amylase | | 分子名称: | Alpha-amylase, CALCIUM ION, SODIUM ION | | 著者 | Alikhajeh, J, Khajeh, K, Ranjbar, B, Naderi-Manesh, H, Lin, Y.H, Liu, M.Y, Chen, C.J. | | 登録日 | 2007-11-28 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of Bacillus amyloliquefaciens alpha-amylase at high resolution: implications for thermal stability.
Acta Crystallogr.,Sect.F, 66, 2010
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5WNL
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3ZSG
 | | X-ray structure of p38alpha bound to TAK-715 | | 分子名称: | MITOGEN-ACTIVATED PROTEIN KINASE 14, TAK-715, octyl beta-D-glucopyranoside | | 著者 | Azevedo, R, van Zeeland, M, Raaijmakers, H, Kazemier, B, Oubrie, A. | | 登録日 | 2011-06-28 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | X-ray structure of p38 alpha bound to TAK-715: comparison with three classic inhibitors.
Acta Crystallogr. D Biol. Crystallogr., 68, 2012
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5X2J
 | | Crystal structure of a recombinant hybrid manganese superoxide dismutase from Staphylococcus equorum and Staphylococcus saprophyticus | | 分子名称: | MANGANESE (II) ION, manganese superoxide dismutase | | 著者 | Retnoningrum, D.S, Yoshida, H, Arumsari, S, Kamitori, S, Ismaya, W.T. | | 登録日 | 2017-01-31 | | 公開日 | 2018-01-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The first crystal structure of manganese superoxide dismutase from the genus Staphylococcus
Acta Crystallogr F Struct Biol Commun, 74, 2018
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3ZYY
 | | Reductive activator for corrinoid,iron-sulfur protein | | 分子名称: | (R,R)-2,3-BUTANEDIOL, FE2/S2 (INORGANIC) CLUSTER, IRON-SULFUR CLUSTER BINDING PROTEIN, ... | | 著者 | Hennig, S.E, Jeoung, J.-H, Goetzl, S, Dobbek, H. | | 登録日 | 2011-08-30 | | 公開日 | 2012-04-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Redox-Dependent Complex Formation by an ATP-Dependent Activator of the Corrinoid/Iron-Sulfur Protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5W7C
 | | Human acyloxyacyl hydrolase (AOAH), proteolytically processed, S263A mutant, with LPS | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | | 著者 | Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2017-06-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W98
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8A9O
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8A9N
 | | Structure of DpA polyamine acetyltransferase in complex with 1,3-DAP | | 分子名称: | 1,3-DIAMINOPROPANE, Acetyltransferase, COENZYME A, ... | | 著者 | Garcia-Pino, A, Jurenas, D. | | 登録日 | 2022-06-28 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | | 主引用文献 | A polyamine acetyltransferase regulates the motility and biofilm formation of Acinetobacter baumannii.
Nat Commun, 14, 2023
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8XXL
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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5OMX
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3ZFW
 | | Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | | 分子名称: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | | 著者 | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | | 登録日 | 2012-12-12 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Basis for Kinesin-1:Cargo Recognition.
Science, 340, 2013
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5BYL
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3BZQ
 | | High resolution crystal structure of Nitrogen Regulatory Protein (Rv2919c) of Mycobacterium tuberculosis | | 分子名称: | Nitrogen regulatory protein P-II | | 著者 | Reddy, M.C, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2008-01-18 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein.
Protein Sci., 19, 2010
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