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3I68
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Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2
分子名称: Dihydroorotate dehydrogenase homolog, mitochondrial, FLAVIN MONONUCLEOTIDE, ...
著者Deng, X, Phillips, M.A.
登録日2009-07-06
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds.
J.Biol.Chem., 284, 2009
1T3T
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BU of 1t3t by Molmil
Structure of Formylglycinamide synthetase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ...
著者Ealick, S.E, Anand, R, Hoskin, A.A, Stubbe, J.
登録日2004-04-27
公開日2004-09-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray crystallography
Biochemistry, 43, 2004
8UQ3
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Structure of human RyR2-S2808D in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ2
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Structure of human RyR2-S2808D in the subprimed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ4
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Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
1T4B
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1.6 Angstrom structure of Esherichia coli aspartate-semialdehyde dehydrogenase.
分子名称: Aspartate-semialdehyde dehydrogenase, SODIUM ION
著者Nichols, C.E, Dhaliwal, B, Lockyer, M, Hawkins, A.R, Stammers, D.K.
登録日2004-04-29
公開日2004-07-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution Structures Reveal Details of Domain Closure and "Half-of-sites-reactivity" in Escherichia coli Aspartate beta-Semialdehyde Dehydrogenase.
J.Mol.Biol., 341, 2004
3I6R
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BU of 3i6r by Molmil
Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM74
分子名称: 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase homolog, mitochondrial, ...
著者Deng, X, Phillips, M.A.
登録日2009-07-07
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds.
J.Biol.Chem., 284, 2009
1T11
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Trigger Factor
分子名称: Trigger factor
著者Ludlam, A.V, Moore, B.A, Xu, Z.
登録日2004-04-14
公開日2004-09-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae.
Proc.Natl.Acad.Sci.USA, 101, 2004
1TA4
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Crystal Structure Of Aspartate-Semialdehyde Dehydrogenase From Haemophilus Influenzae with a Bound Arsenate
分子名称: ARSENATE, Aspartate-semialdehyde dehydrogenase
著者Viola, R.E.
登録日2004-05-19
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
3I65
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Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM1
分子名称: 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase homolog, mitochondrial, ...
著者Deng, X, Phillips, M.A.
登録日2009-07-06
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds.
J.Biol.Chem., 284, 2009
3EXT
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BU of 3ext by Molmil
Crystal structure of KGPDC from Streptococcus mutans
分子名称: MAGNESIUM ION, RmpD (Hexulose-6-phosphate synthase)
著者Liu, X, Li, G.L, Li, L.F, Su, X.D.
登録日2008-10-17
公開日2009-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Open-closed conformational change revealed by the crystal structures of 3-keto-L-gulonate 6-phosphate decarboxylase from Streptococcus mutans
Biochem.Biophys.Res.Commun., 381, 2009
1B6R
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BU of 1b6r by Molmil
N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE FROM E. COLI
分子名称: PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE), SULFATE ION
著者Thoden, J.B, Kappock, T.J, Stubbe, J, Holden, H.M.
登録日1999-01-17
公開日1999-11-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
Biochemistry, 38, 1999
1TV5
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Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor
分子名称: (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, Dihydroorotate dehydrogenase homolog, ...
著者Hurt, D.E, Widom, J, Clardy, J.
登録日2004-06-27
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor.
Acta Crystallogr.,Sect.D, 62, 2006
3PPC
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Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, tyrosine variant with zinc
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, CHLORIDE ION, ZINC ION
著者Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
登録日2010-11-24
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
3KRE
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BU of 3kre by Molmil
Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-11-18
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution
To be Published
1TWJ
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BU of 1twj by Molmil
Crystal Structure of B. subtilis PurS P21 Crystal Form
分子名称: Hypothetical UPF0062 protein yexA
著者Anand, R, Ealick, S.E, Hoskins, A.A, Stubbe, J.
登録日2004-07-01
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Model for the Bacillus subtilis Formylglycinamide Ribonucleotide Amidotransferase Multiprotein Complex
Biochemistry, 43, 2004
3PPF
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Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant without zinc
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
著者Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
登録日2010-11-24
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
1UMY
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BHMT from rat liver
分子名称: BETA-MERCAPTOETHANOL, Betaine--homocysteine S-methyltransferase 1, ZINC ION
著者Gonzalez, B, Pajares, M.A, Sanz-Aparicio, J.
登録日2003-09-02
公開日2004-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding.
J. Mol. Biol., 338, 2004
3OET
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BU of 3oet by Molmil
D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD
分子名称: Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Edwards, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-08-13
公開日2010-08-25
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD
To be Published
1SO6
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Crystal structure of E112Q/H136A double mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
1SO3
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Crystal structure of H136A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
3L7R
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crystal structure of MetE from streptococcus mutans
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION
著者Fu, T.M, Liang, Y.H, Su, X.D.
登録日2009-12-29
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
J.Mol.Biol., 412, 2011
3LP6
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Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution
分子名称: FORMIC ACID, GLYCEROL, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Kim, H, Yu, M, Hung, L.-W, Terwilliger, T.C, Kim, C.-Y, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
登録日2010-02-04
公開日2010-06-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A Resolution
To be Published
3PNU
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2.4 Angstrom Crystal Structure of Dihydroorotase (pyrC) from Campylobacter jejuni.
分子名称: Dihydroorotase, PHOSPHATE ION, ZINC ION
著者Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-11-19
公開日2010-12-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2.4 Angstrom Crystal Structure of Dihydroorotase (pyrC) from Campylobacter jejuni.
TO BE PUBLISHED
3PPH
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Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, threonine variant
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
著者Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
登録日2010-11-24
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011

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