1TV5

Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor

Summary for 1TV5

Entry DOI	10.2210/pdb1tv5/pdb
Descriptor	Dihydroorotate dehydrogenase homolog, mitochondrial, SULFATE ION, (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, ... (7 entities in total)
Functional Keywords	alpha-beta barrel; tim barrel, oxidoreductase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Cellular location	Mitochondrion inner membrane (By similarity); Single-pass membrane protein (Potential): Q08210
Total number of polymer chains	1
Total formula weight	51939.95
Authors	Hurt, D.E.,Widom, J.,Clardy, J. (deposition date: 2004-06-27, release date: 2005-09-06, Last modification date: 2023-08-23)
Primary citation	Hurt, D.E.,Widom, J.,Clardy, J. Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor. Acta Crystallogr.,Sect.D, 62:312-323, 2006 Cited by PubMed: 16510978 DOI: 10.1107/S0907444905042642 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation