1TV5

Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dihydroorotate dehydrogenase homolog, mitochondrial	polymer	443	50260.3	1	UniProt (Q08210) Pfam (PF01180) In PDB	Plasmodium falciparum (malaria parasite P. falciparum)	Dihydroorotate oxidase; DHOdehase; dihydroorotate dehydrogenase
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A	(2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide	non-polymer		270.2	1	Chemie (A26)
4	A	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)
5	A	OROTIC ACID	non-polymer		156.1	1	Chemie (ORO)
6	A	3,6,9,12,15-PENTAOXATRICOSAN-1-OL	non-polymer		350.5	2	Chemie (N8E)
7		water	water		18.0	212	Chemie (HOH)

Sequence modifications

A: 158 - 569 (UniProt: Q08210)

PDB	External Database	Details
Met 127	-	insertion
Arg 128	-	insertion
Gly 129	-	insertion
Ser 130	-	insertion
His 131	-	insertion
His 132	-	insertion
His 133	-	insertion
His 134	-	insertion
His 135	-	insertion
His 136	-	insertion
Gly 137	-	insertion
Met 138	-	insertion
Ala 139	-	insertion
Ser 140	-	insertion
Met 141	-	insertion
Thr 142	-	insertion
Gly 143	-	insertion
Gly 144	-	insertion
Gln 145	-	insertion
Gln 146	-	insertion
Met 147	-	insertion
Gly 148	-	insertion
Arg 149	-	insertion
Asp 150	-	insertion
Leu 151	-	insertion
Tyr 152	-	insertion
Asp 153	-	insertion
Asp 154	-	insertion
Asp 155	-	insertion
Asp 156	-	insertion
Lys 157	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50260.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1679.7
All*	Total formula weight	51940.0

*Water molecules are not included.