PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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5MW6	Crystal structure of the BCL6 BTB-domain with compound 1 分子名称: 5-chloranyl-~{N}-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-amine, B-cell lymphoma 6 protein 著者 Davies, D.R, Kessler, D. 登録日 2017-01-18 公開日 2017-10-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep, 20, 2017
6TZD	Crystal Structure of Ketosteroid Isomerase from Pseudomonas Putida (pKSI) bound to 4-Androstenedione at 280 K 分子名称: 4-ANDROSTENE-3-17-DIONE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Yabukarski, F, Herschlag, D. 登録日 2019-08-12 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4507 Å) 主引用文献 Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles. Proc.Natl.Acad.Sci.USA, 117, 2020
5M9P	Human angiogenin ALS variant T80S 分子名称: Angiogenin, SULFATE ION 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-02 公開日 2017-02-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
6TZH	ADC-7 in complex with boronic acid transition state inhibitor S06015 分子名称: Beta-lactamase, GLYCINE, PHOSPHATE ION, ... 著者 Fish, E.R, Powers, R.A, Wallar, B.J. 登録日 2019-08-12 公開日 2020-06-24 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-Lactamase Inhibitors againstAcinetobacter baumanniiCephalosporinase. Acs Infect Dis., 6, 2020
5MWD	Crystal structure of the BCL6 BTB-domain with compound 2 分子名称: 5-[[5-chloranyl-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one, B-cell lymphoma 6 protein 著者 Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A. 登録日 2017-01-18 公開日 2017-10-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep, 20, 2017
6TZZ	Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with Magnesium 分子名称: MAGNESIUM ION, Nuclear elongation and deformation protein 著者 Khayyo, V.I, Airola, M.V. 登録日 2019-08-13 公開日 2020-03-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of a lipin/Pah phosphatidic acid phosphatase Nat Commun, 11, 2020
5MWL	INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCULUS IN COMPLEX WITH ATP and IP5 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Inositol-pentakisphosphate 2-kinase, MAGNESIUM ION, ... 著者 Franco-Echevarria, E, Sanz-Aparicio, J, Gonzalez, B. 登録日 2017-01-18 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function. J. Biol. Chem., 292, 2017
6UNN	The crystal structure of 4-methoxycinnamic acid-bound CYP199A4 分子名称: (E)-3-(4-methoxyphenyl)acrylic acid, CHLORIDE ION, CYP199A4, ... 著者 Doherty, Z.D, Bell, S.G, Bruning, J. 登録日 2019-10-13 公開日 2020-10-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.655 Å) 主引用文献 The crystal structure of 4-methoxycinnamic acid-bound CYP199A4 To Be Published
5MAY	STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2-Thiophenesulfonamide-N-(beta-L-fucopyranosyl methyl) 分子名称: CALCIUM ION, Fucose-binding lectin PA-IIL, N-methyl-2-thiophenesulfonamide, ... 著者 Sommer, R, Imberty, A, Titz, A, Varrot, A. 登録日 2016-11-07 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140, 2018
6RY3	Structure of the WUS homeodomain 分子名称: ACETYL GROUP, Protein WUSCHEL, SULFATE ION 著者 Sloan, J.J, Wild, K, Sinning, I. 登録日 2019-06-10 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.374 Å) 主引用文献 Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. Nat Commun, 11, 2020
6RWH	Fragment AZ-007 binding at a primary and secondary binding site of the the p53pT387/14-3-3 sigma complex 分子名称: 14-3-3 protein sigma, 5-(1~{H}-imidazol-5-yl)-4-phenyl-thiophene-2-carboximidamide, CALCIUM ION, ... 著者 Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. 登録日 2019-06-05 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
5MBQ	CeuE (H227A variant) a periplasmic protein from Campylobacter jejuni 分子名称: Enterochelin uptake periplasmic binding protein 著者 Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. 登録日 2016-11-08 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length. Sci Rep, 7, 2017
6RY7	Crystal structure of Dfg5 from Chaetomium thermophilum in complex with laminaribiose 分子名称: CALCIUM ION, Mannan endo-1,6-alpha-mannosidase, TRIETHYLENE GLYCOL, ... 著者 Essen, L.-O, Vogt, M.S. 登録日 2019-06-10 公開日 2020-08-12 最終更新日 2020-09-16 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural base for the transfer of GPI-anchored glycoproteins into fungal cell walls. Proc.Natl.Acad.Sci.USA, 117, 2020
5M5Z	Chaetomium thermophilum beta-1-3-glucanase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-1,3-glucanase, ... 著者 Papageorgiou, A.C, Chen, J, Li, D. 登録日 2016-10-23 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure and biological implications of a glycoside hydrolase family 55 beta-1,3-glucanase from Chaetomium thermophilum. Biochim. Biophys. Acta, 1865, 2017
5MCE	Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 5.43 MGy 分子名称: Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION 著者 Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. 登録日 2016-11-09 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
6RYW	Copper oxidase from Colletotrichum graminicola 分子名称: COPPER (II) ION, Kelch domain-containing protein, TRIETHYLENE GLYCOL 著者 Offen, W.A, Henrissat, B, Davies, G.J. 登録日 2019-06-12 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5-Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing Acs Catalysis, 2020
6RZL	Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:4(Bromine) 分子名称: (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(3-bromophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-3, THIOCYANATE ION 著者 Kumar, R, Verteramo, M.L, Nilsson, U.J, Logan, D.T. 登録日 2019-06-13 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.045 Å) 主引用文献 Thermodynamic studies of halogen-bond interactions in galectin-3 to be published
5M7I	Crystal structure of GH125 1,6-alpha-mannosidase mutant from Clostridium perfringens in complex with 1,6-alpha-mannobiose 分子名称: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, exo-alpha-1,6-mannosidase 著者 Males, A, Alonso-Gil, S, Fernandes, P, Williams, S.J, Rovira, C, Davies, G.J. 登録日 2016-10-27 公開日 2016-11-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 alpha-Mannosidases. J. Am. Chem. Soc., 139, 2017
5MDS	Crystal structure of outer membrane expressed Chitoporin VhChip from Vibrio harveyi in complex with chitotetraose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitoporin 著者 Zahn, M, van den Berg, B. 登録日 2016-11-13 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for chitin acquisition by marine Vibrio species. Nat Commun, 9, 2018
6RZR	Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed imipenem 分子名称: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ... 著者 Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. 登録日 2019-06-13 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
5M7S	Structure of human O-GlcNAc hydrolase with bound transition state analog ThiametG 分子名称: (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, Protein O-GlcNAcase 著者 Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. 登録日 2016-10-28 公開日 2017-03-29 最終更新日 2017-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
7B29	Complement inhibitor CirpA4 from Rhipicephalus appendiculatus 分子名称: CADMIUM ION, CHLORIDE ION, CirpA4 著者 Lea, S.M, Johnson, S, Braunger, K. 登録日 2020-11-26 公開日 2021-12-08 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13, 2022
7B2A	Complement inhibitor CirpA5 from Rhipicephalus appendiculatus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CirpA5 著者 Lea, S.M, Johnson, S, Braunger, K. 登録日 2020-11-26 公開日 2021-12-08 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13, 2022
6S5Z	Structure of Rib R28N from Streptococcus pyogenes 分子名称: SODIUM ION, Surface protein R28 著者 Whelan, F, Griffiths, S.C, Whittingham, J.L, Bateman, A, Potts, J.R. 登録日 2019-07-02 公開日 2019-12-11 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection. Proc.Natl.Acad.Sci.USA, 116, 2019
6S63	Dark-adapted structure of Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich at room temperature 分子名称: Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... 著者 Moraes, I, Judge, P.J, Axford, D, Bada Juarez, J.F, Vinals, J, Watts, A. 登録日 2019-07-02 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Two states of a light-sensitive membrane protein captured at room temperature using thin-film sample mounts. Acta Crystallogr D Struct Biol, 78, 2022

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