6HQH
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5CEE
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![BU of 5cee by Molmil](/molmil-images/mine/5cee) | Malic enzyme from Candidatus Phytoplasma AYWB in complex with NAD and Mg2+ | 分子名称: | MAGNESIUM ION, NAD-dependent malic enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Alvarez, C.E, Trajtenberg, F, Larrieux, N, Saigo, M, Mussi, M.A, Andreo, C.S, Drincovich, M.F, Buschiazzo, A. | 登録日 | 2015-07-06 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme. Acta Crystallogr D Struct Biol, 74, 2018
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6T8Z
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![BU of 6t8z by Molmil](/molmil-images/mine/6t8z) | NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A ternary complex with the oxidised form of the cofactor NAD+ and the substrate formate both at a primary and secondary sites. | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | 著者 | Isupov, M.N, Yelmazer, B, De Rose, S.A, Littlechild, J.A. | 登録日 | 2019-10-25 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme. J.Struct.Biol., 212, 2020
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2OOD
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6TAB
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![BU of 6tab by Molmil](/molmil-images/mine/6tab) | Bd0314 DslA wild-type form 2 | 分子名称: | SLT domain-containing protein, SULFATE ION | 著者 | Lovering, A.L, Harding, C.J. | 登録日 | 2019-10-29 | 公開日 | 2020-07-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus. Nat Commun, 11, 2020
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2OME
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![BU of 2ome by Molmil](/molmil-images/mine/2ome) | Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H) | 分子名称: | C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Pilka, E.S, Guo, K, Rojkova, A, Debreczeni, J.E, Kavanagh, K.L, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-01-22 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H) To be Published
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7CDH
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![BU of 7cdh by Molmil](/molmil-images/mine/7cdh) | Crystal structure of Betaaspartyl dipeptidase from thermophilic keratin degrading Fervidobacterium islandicum-AW-1 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoaspartyl dipeptidase, ... | 著者 | Dhanasingh, I, La, J.W, Lee, D.W, Lee, S.H. | 登録日 | 2020-06-19 | 公開日 | 2020-12-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Functional Characterization of Primordial Protein Repair Enzyme M38 Metallo-Peptidase From Fervidobacterium islandicum AW-1. Front Mol Biosci, 7, 2020
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5CJE
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![BU of 5cje by Molmil](/molmil-images/mine/5cje) | Structure of CYP107L2 | 分子名称: | Cytochrome P450 hydroxylase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Pham, T.-V, Han, S.-H, Kim, J.-H, Kim, D.-H, Kang, L.-W. | 登録日 | 2015-07-14 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of CYP107L2 To Be Published
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4DBC
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![BU of 4dbc by Molmil](/molmil-images/mine/4dbc) | Substrate Activation in Aspartate Aminotransferase | 分子名称: | (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate aminotransferase, ... | 著者 | Toney, M.D, Fisher, A.J, Griswold, W.R. | 登録日 | 2012-01-14 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase. J.Am.Chem.Soc., 134, 2012
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6TJK
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![BU of 6tjk by Molmil](/molmil-images/mine/6tjk) | Crystal Structure of Recombinant GBA in Complex with Bis-Tris Propane. | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rowland, R.J, Davies, G.J. | 登録日 | 2019-11-26 | 公開日 | 2020-06-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | A baculoviral system for the production of human beta-glucocerebrosidase enables atomic resolution analysis. Acta Crystallogr D Struct Biol, 76, 2020
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6TEE
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3BE1
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![BU of 3be1 by Molmil](/molmil-images/mine/3be1) | Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Fragment-Heavy Chain, ... | 著者 | Bostrom, J.M, Wiesmann, C, Appleton, B.A. | 登録日 | 2007-11-15 | 公開日 | 2008-11-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site Science, 323, 2009
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6R4K
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![BU of 6r4k by Molmil](/molmil-images/mine/6r4k) | Structure of beta-glucosidase A from Paenibacillus polymyxa complexed with a monovalent inhibitor | 分子名称: | (2~{S},3~{S},4~{R})-2-[[4-[4-[2-[2-(2-azanylidenehydrazinyl)ethoxy]ethoxy]phenyl]-1,2,3-triazol-1-yl]methyl]pyrrolidine-3,4-diol, Beta-glucosidase A | 著者 | Jimenez-Ortega, E, Sanz-Aparicio, J. | 登録日 | 2019-03-22 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural basis of the inhibition of GH1 beta-glucosidases by multivalent pyrrolidine iminosugars. Bioorg.Chem., 89, 2019
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6R6V
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![BU of 6r6v by Molmil](/molmil-images/mine/6r6v) | Structure of recombinant human butyrylcholinesterase in complex with a fluorescent coumarin-based probe | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... | 著者 | Brazzolotto, X, Nachon, F, Knez, D, Gobec, S. | 登録日 | 2019-03-28 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes. J Enzyme Inhib Med Chem, 35, 2020
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6RB5
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![BU of 6rb5 by Molmil](/molmil-images/mine/6rb5) | Trypanothione reductase in complex with 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide | 分子名称: | 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Ilari, A, Fiorillo, A, Battista, T, Mocci, S. | 登録日 | 2019-04-09 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.977 Å) | 主引用文献 | Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme. Plos Negl Trop Dis, 14, 2020
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7C2B
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![BU of 7c2b by Molmil](/molmil-images/mine/7c2b) | Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin f2 complex | 分子名称: | Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, Ferredoxin-thioredoxin reductase variable chain, ... | 著者 | Kurisu, G, Juniar, L, Tanaka, H. | 登録日 | 2020-05-07 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7949 Å) | 主引用文献 | Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity. Protein Sci., 29, 2020
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7C82
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2ONO
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2AL1
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![BU of 2al1 by Molmil](/molmil-images/mine/2al1) | Crystal Structure Analysis of Enolase Mg Subunit Complex at pH 8.0 | 分子名称: | 2-PHOSPHOGLYCERIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Sims, P.A, Menefee, A.L, Larsen, T.M, Mansoorabadi, S.O, Reed, G.H. | 登録日 | 2005-08-04 | 公開日 | 2006-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure and catalytic properties of an engineered heterodimer of enolase composed of one active and one inactive subunit J.Mol.Biol., 355, 2006
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2OR3
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4DB6
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![BU of 4db6 by Molmil](/molmil-images/mine/4db6) | Designed Armadillo repeat protein (YIIIM3AII) | 分子名称: | Armadillo repeat protein | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | 登録日 | 2012-01-13 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins. Protein Sci., 21, 2012
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2VB5
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![BU of 2vb5 by Molmil](/molmil-images/mine/2vb5) | Solution structure of W60G mutant of human beta2-microglobulin | 分子名称: | BETA-2-MICROGLOBULIN | 著者 | Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V. | 登録日 | 2007-09-06 | 公開日 | 2007-09-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties. J.Mol.Biol., 378, 2008
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5BOO
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![BU of 5boo by Molmil](/molmil-images/mine/5boo) | Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265 | 分子名称: | 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Phillips, M, Deng, X, Tomchick, D. | 登録日 | 2015-05-27 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci Transl Med, 7, 2015
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7CGY
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![BU of 7cgy by Molmil](/molmil-images/mine/7cgy) | Human DMC1 Q244M mutant of the post-synaptic complexes | 分子名称: | CALCIUM ION, Meiotic recombination protein DMC1/LIM15 homolog, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y. | 登録日 | 2020-07-03 | 公開日 | 2020-11-18 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. Nat Commun, 12, 2021
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7C9C
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![BU of 7c9c by Molmil](/molmil-images/mine/7c9c) | Human DMC1 pre-synaptic complexes | 分子名称: | CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Meiotic recombination protein DMC1/LIM15 homolog, ... | 著者 | Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D. | 登録日 | 2020-06-05 | 公開日 | 2020-11-25 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. Nat Commun, 12, 2021
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