PDB: 10962 件ウェブページステータス検索Chemie searchBIRD

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1M4R	CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22 分子名称: Interleukin-22 著者 Nagem, R.A.P, Colau, D, Dumoutier, L, Renauld, J.-C, Ogata, C, Polikarpov, I. 登録日 2002-07-03 公開日 2003-07-07 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Recombinant Human Interleukin-22 Structure, 10, 2002
1M16	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V). 分子名称: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor 著者 Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M. 登録日 2002-06-17 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Accommodation of a highly symmetric core within a symmetric protein superfold Protein Sci., 12, 2003
1TDQ	Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins 分子名称: Aggrecan core protein, CALCIUM ION, Tenascin-R 著者 Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. 登録日 2004-05-24 公開日 2004-08-31 最終更新日 2021-03-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins Structure, 12, 2004
1TFK	Ribonuclease from Escherichia coli complexed with its inhibtor protein 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Colicin D, Colicin D immunity protein 著者 Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. 登録日 2004-05-27 公開日 2005-03-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Relation between tRNase activity and the structure of colicin D according to X-ray crystallography Biochem.Biophys.Res.Commun., 322, 2004
1TIP	THE BISPHOSPHATASE DOMAIN OF THE BIFUNCTIONAL RAT LIVER 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 分子名称: 6-O-phosphono-beta-D-fructofuranose, PHOSPHOENZYME INTERMEDIATE OF FRU-2,6-BISPHOSPHATASE 著者 Lee, Y.-H, Olson, T.W, Ogata, C.M, Levitt, D.G, Banaszak, L.J, Lange, A.J. 登録日 1997-05-28 公開日 1998-01-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a trapped phosphoenzyme during a catalytic reaction. Nat.Struct.Biol., 4, 1997
1SU4	Crystal structure of calcium ATPase with two bound calcium ions 分子名称: CALCIUM ION, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 著者 Toyoshima, C, Nakasako, M, Nomura, H, Ogawa, H. 登録日 2004-03-26 公開日 2004-05-04 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution Nature, 405, 2000
1RWF	Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide 分子名称: 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... 著者 Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. 登録日 2003-12-16 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
1RWG	Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide 分子名称: 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... 著者 Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. 登録日 2003-12-16 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
1UA4	Crystal Structure of an ADP-dependent Glucokinase from Pyrococcus furiosus 分子名称: ADENOSINE MONOPHOSPHATE, ADP-dependent glucokinase, alpha-D-glucopyranose, ... 著者 Ito, S, Jeong, J.J, Yoshioka, I, Koga, S, Fushinobu, S, Shoun, H, Wakagi, T. 登録日 2003-02-27 公開日 2004-02-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase J.Mol.Biol., 331, 2003
1RZF	Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51 分子名称: Fab E51 heavy chain, Fab E51 light chain, GLYCEROL, ... 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
1SH2	Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic) 分子名称: RNA Polymerase 著者 Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. 登録日 2004-02-24 公開日 2004-03-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J.Biol.Chem., 279, 2004
1UF2	The Atomic Structure of Rice dwarf Virus (RDV) 分子名称: Core protein P3, Outer capsid protein P8, Structural protein P7 著者 Nakagawa, A, Miyazaki, N, Taka, J, Naitow, H, Ogawa, A, Fujimoto, Z, Mizuno, H, Higashi, T, Watanabe, Y, Omura, T, Cheng, R.H, Tsukihara, T. 登録日 2003-05-23 公開日 2003-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The atomic structure of rice dwarf virus reveals the self-assembly mechanism of component proteins. Structure, 11, 2003
1S3K	Crystal Structure of a Humanized Fab (hu3S193) in Complex with the Lewis Y Tetrasaccharide 分子名称: GLYCEROL, HU3S193 Fab fragment, heavy chain, ... 著者 Ramsland, P.A, Farrugia, W, Bradford, T.M, Hogarth, P.M, Scott, A.M. 登録日 2004-01-13 公開日 2004-07-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural convergence of antibody binding of carbohydrate determinants in lewis y tumor antigens J.Mol.Biol., 340, 2004
1RZ8	CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B 分子名称: Fab 17b heavy chain, Fab 17b light chain 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
1TFO	Ribonuclease from Escherichia coli complexed with its inhibitor protein 分子名称: Colicin D, Colicin D immunity protein 著者 Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. 登録日 2004-05-27 公開日 2005-03-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Relation between tRNase activity and the structure of colicin D according to X-ray crystallography Biochem.Biophys.Res.Commun., 322, 2004
3S57	ABH2 cross-linked with undamaged dsDNA-1 containing cofactors 分子名称: 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*AP*TP*CP*AP*CP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*GP*TP*GP*AP*TP*GP*AP*CP*A)-3', ... 著者 Yi, C, Chen, B, Qi, B, Ramirez, B, Zhang, W, Jia, G, Zhang, L, Li, C.Q, Dinner, A.R, Yang, C.-G, He, C. 登録日 2011-05-20 公開日 2012-06-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Duplex interrogation by a direct DNA repair protein in search of base damage Nat.Struct.Mol.Biol., 19, 2012
1SH0	Crystal Structure of Norwalk Virus Polymerase (Triclinic) 分子名称: RNA Polymerase 著者 Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. 登録日 2004-02-24 公開日 2004-03-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J.Biol.Chem., 279, 2004
1UGL	Solution structure of S8-SP11 分子名称: S-locus pollen protein 著者 Mishima, M, Takayama, S, Sasaki, K, Jee, J.G, Kojima, C, Isogai, A, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-06-16 公開日 2003-09-30 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure of the Male Determinant Factor for Brassica Self-incompatibility J.Biol.Chem., 278, 2003
1RZG	Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d 分子名称: ASPARTIC ACID, CYSTEINE, Fab 412d heavy chain, ... 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
1RZ7	CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D 分子名称: Fab 48d heavy chain, Fab 48d light chain, GLYCEROL 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
1RZI	Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab 分子名称: Fab 47e heavy chain, Fab 47e light chain 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
3R92	Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. 分子名称: (3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14,15,17,18,19-dodecahydro-13H-10,6-(metheno)pyrrolo[2',1':3,4][1,4,9]triazacyclotetradecino[9,8-a]indole-7-carboxamide, Heat shock protein HSP 90-alpha 著者 Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Golas, J.M, Liu, H, Lucas, J, Boschelli, F, Vogan, E.M, Levin, J.I. 登録日 2011-03-24 公開日 2011-06-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5801 Å) 主引用文献 Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Bioorg.Med.Chem.Lett., 21, 2011
3S5A	ABH2 cross-linked to undamaged dsDNA-2 with cofactors 分子名称: 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*TP*CP*AP*CP*TP*GP*TP*CP*G)-3', 5'-D(*TP*CP*GP*AP*CP*AP*GP*TP*GP*AP*GP*AP*CP*A)-3', ... 著者 Yi, C, Chen, B, Qi, B, Ramirez, B, Zhang, W, Jia, G, Zhang, L, Li, C.Q, Dinner, A.R, Yang, C.-G, He, C. 登録日 2011-05-21 公開日 2012-06-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Duplex interrogation by a direct DNA repair protein in search of base damage Nat.Struct.Mol.Biol., 19, 2012
3QTF	Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity 分子名称: (6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-8,12-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha 著者 Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Nittoli, T, Ingalls, C, Sutherland, A.G, Sonye, J.P, Eid, C.N, Golas, J, Liu, H, Boschelli, F, Hu, Y, Vogan, E.M, Levin, J.I. 登録日 2011-02-22 公開日 2011-04-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5703 Å) 主引用文献 Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity. Bioorg.Med.Chem.Lett., 21, 2011
1V8L	Structure Analysis of the ADP-ribose pyrophosphatase complexed with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribose pyrophosphatase 著者 Yoshiba, S, Ooga, T, Nakagawa, N, Shibata, T, Inoue, Y, Yokoyama, S, Kuramitsu, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-01-10 公開日 2004-10-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal J.Biol.Chem., 279, 2004

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