4EKE
 
 | | Crystal structure of GPb in complex with DK11 | | 分子名称: | 3-(beta-D-glucopyranosyl)-6-pentylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form | | 著者 | Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D. | | 登録日 | 2012-04-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
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3PCU
 | | Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide | | 分子名称: | 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | | 著者 | Zhang, H, Zhang, Y, Shen, H, Chen, J, Li, C, Chen, L, Hu, L, Jiang, H, Shen, X. | | 登録日 | 2010-10-22 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | (+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice.
Plos One, 7, 2012
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7SA8
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6BJE
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6VPF
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2ZL8
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6V8T
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6ISW
 | | Structure of human telomeric DNA with 5-selenophene-modified deoxyuridine at residue 12 | | 分子名称: | DNA (22-MER), POTASSIUM ION | | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | | 登録日 | 2018-11-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
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6I8M
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6IP3
 | | Structure of human telomeric DNA at 1.4 Angstroms resolution | | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION | | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | | 登録日 | 2018-11-01 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
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6IX8
 | | The structure of LepI C52A in complex with SAM and its substrate analogue | | 分子名称: | (1R,2R,4aS,8S,8aR)-2,8-dimethyl-5'-phenyl-4a,5,6,7,8,8a-hexahydro-2H,2'H-spiro[naphthalene-1,3'-pyridine]-2',4'(1'H)-dione, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | | 登録日 | 2018-12-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.659 Å) | | 主引用文献 | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 11, 2019
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8PIE
 | | Crystal structure of the human nucleoside diphosphate kinase B domain in complex with the product AT-8500 formed by catalysis of compound AT-9010 | | 分子名称: | GLYCEROL, Nucleoside diphosphate kinase B, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate | | 著者 | Feracci, M, Chazot, A, Ferron, F, Alvarez, K, Canard, B. | | 登録日 | 2023-06-21 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution.
Plos Biol., 22, 2024
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6IX5
 | | The structure of LepI complex with SAM and its substrate analogue | | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, CHLORIDE ION, ... | | 著者 | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | | 登録日 | 2018-12-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 11, 2019
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8JKU
 | | Ancestral imine reductase N559 | | 分子名称: | Ancestral imine reductase N559, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhu, X.X, Zheng, G.W. | | 登録日 | 2023-06-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction.
Nat Commun, 15, 2024
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6IX3
 | | The structure of LepI complex with SAM | | 分子名称: | CHLORIDE ION, O-methyltransferase lepI, S-ADENOSYLMETHIONINE | | 著者 | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | | 登録日 | 2018-12-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 11, 2019
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9CTE
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4ZGW
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7D8G
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6IP7
 | | Structure of human telomeric DNA with 5-Selenophene-modified deoxyuridine at residue 11 | | 分子名称: | DNA (22-MER), POTASSIUM ION | | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
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7UJ7
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6IX9
 | | The structure of LepI C52A in complex with SAM and leporin C | | 分子名称: | (6R,6aS,10S,10aR)-10-methyl-4-phenyl-6-[(1E)-prop-1-en-1-yl]-2,6,6a,7,8,9,10,10a-octahydro-1H-[2]benzopyrano[4,3-c]pyridin-1-one, CHLORIDE ION, GLYCEROL, ... | | 著者 | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | | 登録日 | 2018-12-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | | 主引用文献 | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 11, 2019
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6IX7
 | | The structure of LepI C52A in complex with SAH and substrate analogue | | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, CHLORIDE ION, ... | | 著者 | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | | 登録日 | 2018-12-09 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.835 Å) | | 主引用文献 | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 11, 2019
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8HJZ
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8HJX
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8HJY
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