PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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6EVC	Structure of E282Q A. niger Fdc1 in complex with pentafluoro-cinnamic acid 分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ... 著者 Bailey, S.S, David, L, Payne, K.A.P. 登録日 2017-11-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis. J. Biol. Chem., 293, 2018
2WWY	Structure of human RECQ-like helicase in complex with a DNA substrate 分子名称: 1,2-ETHANEDIOL, 5'-D(*DA DG DC DG DT DC DG DA DG DA DT DC DCP)-3', ATP-DEPENDENT DNA HELICASE Q1, ... 著者 Pike, A.C.W, Zhang, Y, Schnecke, C, Chaikuad, A, Krojer, T, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gileadi, O. 登録日 2009-10-30 公開日 2009-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures Proc.Natl.Acad.Sci.USA, 112, 2015
6C1O	FGFR1 kinase domain complexed with FIIN-1 分子名称: Fibroblast growth factor receptor 1, N-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)prop-2-enamide, SULFATE ION 著者 Kalyukina, M, Yosaatmadja, Y, Smaill, J.B, Squire, C.J. 登録日 2018-01-05 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 A new class of FGFR1 inhibitors To Be Published
1COT	X-RAY STRUCTURE OF THE CYTOCHROME C2 ISOLATED FROM PARACOCCUS DENITRIFICANS REFINED TO 1.7 ANGSTROMS RESOLUTION 分子名称: CYTOCHROME C2, HEME C 著者 Benning, M.M, Meyer, T.E, Holden, H.M. 登録日 1994-07-06 公開日 1994-09-30 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-Ray structure of the cytochrome c2 isolated from Paracoccus denitrificans refined to 1.7-A resolution. Arch.Biochem.Biophys., 310, 1994
6BHU	Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Johnson, Z.L, Chen, J. 登録日 2017-10-31 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1. Cell, 172, 2018
4LCT	Crystal Structure and Versatile Functional Roles of the COP9 Signalosome Subunit 1 分子名称: COP9 signalosome complex subunit 1, SULFATE ION 著者 Lee, J.-H, Yi, L, Li, J, Schweitzer, K, Borgmann, M, Naumann, M, Wu, H. 登録日 2013-06-23 公開日 2013-07-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure and versatile functional roles of the COP9 signalosome subunit 1. Proc.Natl.Acad.Sci.USA, 110, 2013
5AE9	Crystal structure of mouse PI3 kinase delta in complex with GSK2292767 分子名称: N-[5-[4-(5-{[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]METHYL}-1,3-OXAZOL-2-YL)-1H-INDAZOL-6-YL]-2-(METHYLOXY)-3-PYRIDINYL]METHANESULFONAMIDE, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 著者 Down, K.D, Amour, A, Baldwin, I.R, Cooper, A.W.J, Deakin, A.M, Felton, L.M, Guntrip, S.B, Hardy, C, Harrison, Z.A, Jones, K.L, Jones, P, Keeling, S.E, Le, J, Livia, S, Lucas, F, Lunniss, C.J, Parr, N.J, Robinson, E, Rowland, P, Smith, S, Thomas, D.A, Vitulli, G, Washio, Y, Hamblin, N. 登録日 2015-08-26 公開日 2015-09-16 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase Gamma for the Treatment of Respiratory Disease. J.Med.Chem., 58, 2015
7D8U	Crystal structure of the C-terminal domain of pNP868R from African swine fever virus 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, GTP--RNA guanylyltransferase, ... 著者 Du, X, Geng, Z, Zhang, H. 登録日 2020-10-10 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and Biochemical Characteristic of the Methyltransferase (MTase) Domain of RNA Capping Enzyme from African Swine Fever Virus. J.Virol., 2020
2V4N	Crystal structure of Salmonella typhimurium SurE at 1.7 angstrom resolution in orthorhombic form 分子名称: GLYCEROL, MAGNESIUM ION, MULTIFUNCTIONAL PROTEIN SUR E, ... 著者 Anju, P, Savithri, H.S, Murthy, M.R.N. 登録日 2008-09-26 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Functional Studies on a Mesophilic Stationary Phase Survival Protein (Sur E) from Salmonella Typhimurium FEBS J., 275, 2008
1L4F	The crystal structure of CobT complexed with 4,5-dimethyl-1,2-phenylenediamine and nicotinate mononucleotide 分子名称: 4,5-DIMETHYL-1,2-PHENYLENEDIAMINE, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 著者 Cheong, C.-G, Escalante-Semerena, J, Rayment, I. 登録日 2002-03-06 公開日 2002-09-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica. J.Biol.Chem., 277, 2002
2VBG	The complex structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis with 2R-1-hydroxyethyl-deazaThDP 分子名称: 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-[(1R)-1-HYDROXYETHYL]-3-METHYL-2-THIENYL}ETHYL TRIHYDROGEN DIPHOSPHATE, BRANCHED-CHAIN ALPHA-KETOACID DECARBOXYLASE, MAGNESIUM ION 著者 Berthold, C.L, Gocke, D, Wood, M.D, Leeper, F, Pohl, M, Schneider, G. 登録日 2007-09-12 公開日 2007-11-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of the Branched-Chain Keto Acid Decarboxylase (Kdca) from Lactococcus Lactis Provides Insights Into the Structural Basis for the Chemo- and Enantioselective Carboligation Reaction Acta Crystallogr.,Sect.D, 63, 2007
5SNU	PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z2856434770 分子名称: 1-(3-chlorophenyl)-N-methylmethanamine, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... 著者 Brenk, R, Georgiou, C. 登録日 2022-05-30 公開日 2023-12-20 最終更新日 2025-05-07 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Towards new antibiotics: P. aeruginosa FabF ligands discovered by crystallographic fragment screening followed by hit expansion. Eur.J.Med.Chem., 291, 2025
7B6V	Sheep Polyomavirus VP1 in complex with 5 mM Forssman antigen pentaose and 20 mM 3'-sialyllactosamine 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... 著者 Rustmeier, N.H, Stehle, T. 登録日 2020-12-08 公開日 2022-09-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus Biorxiv, 2023
1L8P	Mg-phosphonoacetohydroxamate complex of S39A yeast enolase 1 分子名称: MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID, enolase 1 著者 Poyner, R.R, Larsen, T.M, Wong, S.W, Reed, G.H. 登録日 2002-03-21 公開日 2002-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase. Arch.Biochem.Biophys., 401, 2002
3PXR	Apo CDK2 crystallized from Jeffamine 分子名称: 1,2-ETHANEDIOL, Cell division protein kinase 2 著者 Betzi, S, Alam, R, Schonbrunn, E. 登録日 2010-12-10 公開日 2011-02-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a Potential Allosteric Ligand Binding Site in CDK2. Acs Chem.Biol., 6, 2011
4AUD	Crystal structure of alternaria alternata major allergen alt a 1 分子名称: MAJOR ALLERGEN ALT A 1 SUBUNIT, SULFATE ION 著者 Mechaly, A.E, Ibanez de Opakua, A, Asturias, J, Viguera, A.R. 登録日 2012-05-16 公開日 2013-05-29 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Crystal Structure of Major Allergen of Alternaria Alternata Alt a 1 To be Published
4L8O	Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from Clostridium hylemonae DSM 15053 at 2.20 A resolution 分子名称: 1,2-ETHANEDIOL, Bile acid 7a-dehydratase, BaiE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-06-17 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a bile-acid 7-alpha dehydratase (CLOHYLEM_06634) from Clostridium hylemonae DSM 15053 at 2.20 A resolution To be published
5DNC	Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant T19A 分子名称: 1,2-ETHANEDIOL, ASPARAGINE, L-asparaginase 著者 Schalk, A.M, Lavie, A. 登録日 2015-09-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases. J.Biol.Chem., 291, 2016
5E9Z	Cytochrome P450 BM3 mutant M11 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Bifunctional cytochrome P450/NADPH--P450 reductase, FE (II) ION, ... 著者 Capoferri, L, Leth, R, ter Haar, E, Mohanty, A.K, Grootenhuis, D.J, Vottero, E, Commandeur, J.N.M, Vermeulen, N.P.E, Jorgensen, F.S, Olsen, L, Geerke, D.P. 登録日 2015-10-15 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations. Proteins, 84, 2016
3IDM	Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide analog ELD(Nrg)WAS 分子名称: 2F5 Fab heavy chain, 2F5 Fab light chain, gp41 MPER peptide analog 著者 Julien, J.-P, Bryson, S, Pai, E.F. 登録日 2009-07-21 公開日 2010-02-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
4AU7	The structure of the Suv4-20h2 ternary complex with histone H4 分子名称: 1,2-ETHANEDIOL, HISTONE H4 PEPTIDE, HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2, ... 著者 Southall, S.M, Cronin, N.B, Wilson, J.R. 登録日 2012-05-14 公開日 2013-05-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 A Novel Route to Product Specificity in the Suv4-20 Family of Histone H4K20 Methyltransferases. Nucleic Acids Res., 42, 2014
2V8C	Mouse Profilin IIa in complex with the proline-rich domain of VASP 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ... 著者 Kursula, P, Downer, J, Witke, W, Wilmanns, M. 登録日 2007-08-06 公開日 2007-12-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp. J.Mol.Biol., 375, 2008
4LC8	Crystal structure of the mutant H128N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP 分子名称: 1,2-ETHANEDIOL, 6-HYDROXYURIDINE-5'-PHOSPHATE, CHLORIDE ION, ... 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2013-06-21 公開日 2013-07-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.318 Å) 主引用文献 Crystal structure of the mutant H128N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP To be Published
6BOZ	Structure of human SETD8 in complex with covalent inhibitor MS4138 分子名称: 1,2-ETHANEDIOL, N-(3-{[7-(2-aminoethoxy)-6-methoxy-2-(pyrrolidin-1-yl)quinazolin-4-yl]amino}propyl)prop-2-enamide, N-lysine methyltransferase KMT5A 著者 Babault, N, Anqi, M, Jin, J. 登録日 2017-11-21 公開日 2019-05-01 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The dynamic conformational landscape of the protein methyltransferase SETD8. Elife, 8, 2019
7AE4	Structure of Sedimentibacter hydroxybenzoicus vanillic acid decarboxylase (ShVdcCD) in closed form 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Marshall, S.A, Leys, D. 登録日 2020-09-17 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Domain mobility and allosteric activation of UbiD decarboxylases To Be Published

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