PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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4GJE	Crystal structure of the refolded amino-terminal domain of human cardiac troponin C in complex with cadmium 分子名称: ACETATE ION, CADMIUM ION, CALCIUM ION, ... 著者 Zhang, X, Paetzel, M. 登録日 2012-08-09 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D, 69, 2013
4UWV	Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 8) 分子名称: CARBON MONOXIDE, CHLORIDE ION, LYSOZYME C, ... 著者 Santos, M.F.A, Mukhopadhyay, A, Romao, M.J, Romao, C.C, Santos-Silva, T. 登録日 2014-08-14 公開日 2014-12-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A Contribution to the Rational Design of Ru(Co)3Cl2L Complexes for in Vivo Delivery of Co. Dalton Trans, 44, 2015
3M5N	Crystal structure of HCV NS3/4A protease in complex with N-terminal product 4B5A 分子名称: NS3/4A, SECTTPC peptide, SULFATE ION, ... 著者 Schiffer, C.A, Romano, K.P. 登録日 2010-03-12 公開日 2010-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc.Natl.Acad.Sci.USA, 107, 2010
4GJF	Crystal structure of the amino-terminal domain of human cardiac troponin C mutant L29Q in complex with cadmium 分子名称: ACETATE ION, CADMIUM ION, CALCIUM ION, ... 著者 Zhang, X, Paetzel, M. 登録日 2012-08-09 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D, 69, 2013
4GJG	Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium. 分子名称: ACETATE ION, CADMIUM ION, CALCIUM ION, ... 著者 Zhang, X, Paetzel, M. 登録日 2012-08-09 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination. Acta Crystallogr.,Sect.D, 69, 2013
2GJ7	Crystal Structure of a gE-gI/Fc complex 分子名称: Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J. 登録日 2006-03-30 公開日 2006-05-30 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging. Plos Biol., 4, 2006
5I7X	BRD9 in complex with Cpd2 (N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide) 分子名称: Bromodomain-containing protein 9, N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide 著者 Murray, J.M. 登録日 2016-02-18 公開日 2016-10-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.1752 Å) 主引用文献 Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
4P5W	Structure of the N- and C-terminal domain fusion of the human mitochondrial aspartate/glutamate carrier Citrin in the calcium-bound state 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein Aralar2,Calcium-binding mitochondrial carrier protein Aralar2 著者 Thangaratnarajah, C, Ruprecht, J.J, Kunji, E.R.S. 登録日 2014-03-20 公開日 2014-11-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers. Nat Commun, 5, 2014
4UCA	N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein 分子名称: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION 著者 Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. 登録日 2014-12-03 公開日 2015-08-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
4G9Z	Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression 分子名称: Nucleoprotein, RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), ... 著者 Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C, Scottish Structural Proteomics Facility (SSPF) 登録日 2012-07-24 公開日 2013-04-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression. J.Biol.Chem., 288, 2013
6E3R	Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-14 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
6E3V	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
6E3W	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
2G1N	Ketopiperazine-based renin inhibitors: Optimization of the "C" ring 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOTHIAZIN-4-YL]ETHYL}ACETAMIDE, Renin 著者 Holsworth, D.D. 登録日 2006-02-14 公開日 2006-06-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Ketopiperazine-based renin inhibitors: Optimization of the "C" ring BIOORG.MED.CHEM.LETT., 16, 2006
7S5O	Crystal structure of Cytochrome c' beta from Nitrosomonas europaea ATCC 19718 分子名称: ACETATE ION, Cytochrome_P460 domain-containing protein, HEME C, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-09-11 公開日 2022-03-30 最終更新日 2022-04-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Characterization of Cytochrome c ' beta-Met from an Ammonia-Oxidizing Bacterium. Biochemistry, 61, 2022
5AC3	Crystal structure of PAM12A 分子名称: ACETIC ACID, CADMIUM ION, PEPTIDE AMIDASE 著者 Wu, B, Wijma, H.J, Song, L, Rozeboom, H.J, Poloni, C, Tian, Y, Arif, M.I, Nuijens, T, Quadflieg, P.J.L.M, Szymanski, W, Feringa, B.L, Janssen, D.B. 登録日 2015-08-11 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Versatile Peptide C-Terminal Functionalization Via a Computationally Peptide Amidase Acs Catalysis, 2016
3M5O	Crystal structure of HCV NS3/4A protease in complex with N-terminal product 5A5B 分子名称: NS3/4A, SULFATE ION, TEDVVCC peptide, ... 著者 Schiffer, C.A, Romano, K.P. 登録日 2010-03-12 公開日 2010-11-24 最終更新日 2017-08-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc.Natl.Acad.Sci.USA, 107, 2010
6DO2	Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine 分子名称: 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Endoplasmic reticulum chaperone BiP 著者 Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. 登録日 2018-06-08 公開日 2019-06-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine To Be Published
3LOX	HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound 分子名称: (1R,2S,5S)-N-[(2S,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl]-6,6-dimethyl-3-{3-methyl-N-[(1-methylcyclohexyl)c arbamoyl]-L-valyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, BETA-MERCAPTOETHANOL, HCV NS3 Protease, ... 著者 Prongay, A.J. 登録日 2010-02-04 公開日 2011-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor. Bioorg.Med.Chem.Lett., 20, 2010
4UC8	N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal phenylalanine of the Phosphoprotein 分子名称: GLYCEROL, NUCLEOPROTEIN, PHENYLALANINE, ... 著者 Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. 登録日 2014-12-03 公開日 2015-08-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
6R8O	Human Cyclophilin D in complex with 1-(((2R,3S,6R)-3-hydroxy-2,3,4,6-tetrahydro-1H-2,6-methanobenzo[c][1,5]oxazocin-8-yl)methyl)-3-(2-((R)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea 分子名称: 1-(((2R,3S,6R)-3-hydroxy-2,3,4,6-tetrahydro-1H-2,6-methanobenzo[c][1,5]oxazocin-8-yl)methyl)-3-(2-((R)-2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxoethyl)urea, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase F, ... 著者 Graedler, U. 登録日 2019-04-02 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies. Bioorg.Med.Chem.Lett., 29, 2019
5HUZ	Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase 分子名称: Protein phosphatase 1 regulatory subunit 12A 著者 Sharma, A.K, Birrane, G, Anklin, C, Rigby, A.C, Pollak, M, Alper, S.L. 登録日 2016-01-27 公開日 2016-03-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 To be published To Be Published
2RB3	Crystal Structure of Human Saposin D 分子名称: GLYCEROL, Proactivator polypeptide, SULFATE ION 著者 Maier, T, Rossman, M, Saenger, W. 登録日 2007-09-18 公開日 2008-04-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions. Structure, 16, 2008
4PDZ	Crystal Structure of Calcium-loaded S100B bound to SBi4172 分子名称: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, CALCIUM ION, Protein S100-B 著者 Cavalier, M.C, Pierce, A.D, Wilder, P.T, Neau, D, Toth, E.A, Weber, D.J. 登録日 2014-04-22 公開日 2014-10-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B. Biochemistry, 53, 2014
4WH6	Crystal structure of HCV NS3/4A protease variant R155K in complex with Asunaprevir 分子名称: Genome polyprotein, N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-L-prolinamide, SULFATE ION, ... 著者 Soumana, D.I, Ali, A, Schiffer, C.A. 登録日 2014-09-20 公開日 2014-10-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease. Acs Chem.Biol., 9, 2014

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