PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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5MNG	Cationic trypsin in complex with benzamidine (deuterated sample at 100 K) 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-12-13 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.86 Å) 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
5MNZ	Neutron structure of cationic trypsin in its apo form 分子名称: CALCIUM ION, Cationic trypsin 著者 Schiebel, J, Schrader, T.E, Ostermann, A, Heine, A, Klebe, G. 登録日 2016-12-13 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 NEUTRON DIFFRACTION (1.45 Å) 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
5MOS	Joint X-ray/neutron structure of cationic trypsin in complex with N-amidinopiperidine 分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ... 著者 Schiebel, J, Schrader, T.E, Ostermann, A, Heine, A, Klebe, G. 登録日 2016-12-14 公開日 2018-02-28 最終更新日 2024-05-01 実験手法 NEUTRON DIFFRACTION (0.96 Å), X-RAY DIFFRACTION 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
6D40	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: Plasminogen, SULFATE ION, Trypsin inhibitor 1 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
6D3Y	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: GLYCEROL, Plasminogen, SULFATE ION, ... 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
5MNH	Cationic trypsin in complex with benzamidine (deuterated sample at 295 K) 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-12-13 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
5MNO	Cationic trypsin in complex with N-amidinopiperidine (deuterated sample at 295 K) 分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-12-13 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
5MOQ	Joint X-ray/neutron structure of cationic trypsin in complex with benzamidine 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Schiebel, J, Schrader, T.E, Ostermann, A, Heine, A, Klebe, G. 登録日 2016-12-14 公開日 2018-02-28 最終更新日 2024-05-01 実験手法 NEUTRON DIFFRACTION (0.93 Å), X-RAY DIFFRACTION 主引用文献 Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9, 2018
6D3X	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: Plasminogen, Trypsin inhibitor 1 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
2FMJ	220-loop mutant of streptomyces griseus trypsin 分子名称: CALCIUM ION, SULFATE ION, Trypsin 著者 Page, M.J, Di Cera, E. 登録日 2006-01-09 公開日 2006-05-23 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Conversion of trypsin into a Na(+)-activated enzyme. Biochemistry, 45, 2006
1ANC	ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY LYS 分子名称: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION 著者 Fletterick, R.J, Mcgrath, M.E. 登録日 1994-12-21 公開日 1997-04-01 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. Biochemistry, 31, 1992
1ANB	ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU 分子名称: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION 著者 Fletterick, R.J, Mcgrath, M.E. 登録日 1994-12-21 公開日 1997-04-01 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. Biochemistry, 31, 1992
3RDZ	Crystal Structure of rBTI-trypsin complex at 2.26 angstrom resolution 分子名称: BWI-1=PROTEASE inhibitor/trypsin inhibitor, CALCIUM ION, Cationic trypsin 著者 Wang, L.F, Li, M, Chang, W.R. 登録日 2011-04-02 公開日 2011-07-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.262 Å) 主引用文献 Conformational Changes of rBTI from Buckwheat upon Binding to Trypsin: Implications for the Role of the P(8)' Residue in the Potato Inhibitor I Family Plos One, 6, 2011
2TIO	LOW PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE 分子名称: BENZAMIDINE, CALCIUM ION, HEXANE, ... 著者 Huang, Q, Zhu, G, Tang, Q. 登録日 1998-09-23 公開日 1998-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. Biochim.Biophys.Acta, 1429, 1998
3VPK	Crystal Structure of 6-Guanidinohexanoyl Trypsin 分子名称: 6-carbamimidamidohexanoic acid, CALCIUM ION, Cationic trypsin, ... 著者 Masuda, Y, Nitanai, Y, Mizutani, R, Noguchi, S. 登録日 2012-03-05 公開日 2012-05-23 最終更新日 2013-02-06 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylated Proteins, 2012
2TLD	CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN 分子名称: STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN 著者 Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T. 登録日 1991-09-16 公開日 1992-07-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin. Proc.Natl.Acad.Sci.USA, 89, 1992
1V6D	The crystal structure of the trypsin complex with synthetic heterochiral peptide 分子名称: ACETATE ION, CALCIUM ION, METHYLAMINE, ... 著者 Shamaladevi, N, Pattabhi, V. 登録日 2003-11-28 公開日 2004-12-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Secondary binding site of trypsin: revealed by crystal structure of trypsin-peptide complex. J.Biomol.Struct.Dyn., 22, 2005
3P95	Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17D) 分子名称: CALCIUM ION, PRSS3 protein, Pancreatic trypsin inhibitor 著者 Salameh, M.A, Soares, A.S, Radisky, E.S. 登録日 2010-10-15 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.2991 Å) 主引用文献 The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity. Biochem.J., 440, 2011
2VU8	Crystal structure of an insect inhibitor with a fungal trypsin 分子名称: PACIFASTIN-RELATED SERINE PROTEASE INHIBITOR, TRYPSIN 著者 Leone, P, Roussel, A, Kellenberger, C. 登録日 2008-05-21 公開日 2008-12-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Locusta Migratoria Protease Inhibitor 3 (Lmpi-3) in Complex with Fusarium Oxysporum Trypsin. Acta Crystallogr.,Sect.D, 64, 2008
2TRM	THE THREE-DIMENSIONAL STRUCTURE OF ASN102 MUTANT OF TRYPSIN. ROLE OF ASP102 IN SERINE PROTEASE CATALYSIS 分子名称: BENZAMIDINE, CALCIUM ION, TRYPSIN 著者 Stroud, R.M, Finer-Moore, J. 登録日 1988-04-25 公開日 1988-07-16 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis. Science, 237, 1987
3P92	Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17G) 分子名称: CALCIUM ION, PRSS3 protein, Pancreatic trypsin inhibitor 著者 Salameh, M.A, Soares, A.S, Radisky, E.S. 登録日 2010-10-15 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5992 Å) 主引用文献 The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity. Biochem.J., 440, 2011
4DOQ	Crystal structure of the complex of Porcine Pancreatic Trypsin with 1/2SLPI 分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Antileukoproteinase, CALCIUM ION, ... 著者 Fukushima, K, Takimoto-Kamimura, M. 登録日 2012-02-10 公開日 2013-08-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure basis 1/2SLPI and porcine pancreas trypsin interaction J.SYNCHROTRON RADIAT., 20, 2013
2ILN	Crystal structure of the Bowman-Birk inhibitor from snail medic seeds in complex with bovine trypsin 分子名称: Bowman-Birk type proteinase inhibitor, Cationic trypsin 著者 Capaldi, S, Perduca, M, Faggion, B, Carrizo, M.E, Tava, A, Ragona, L, Monaco, H.L. 登録日 2006-10-03 公開日 2007-04-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the anticarcinogenic Bowman-Birk inhibitor from snail medic (Medicago scutellata) seeds complexed with bovine trypsin J.Struct.Biol., 158, 2007
6SVD	Non-terahertz irradiated structure of bovine trypsin (even frames of crystal x41) 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Ahlberg Gagner, V, Lundholm, I, Garcia-Bonete, M.J, Rodilla, H, Friedman, R, Zhaunerchyk, V, Bourenkov, G, Schneider, T, Stake, J, Katona, G. 登録日 2019-09-18 公開日 2020-01-22 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Clustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties. Sci Rep, 9, 2019
6SVW	Reference structure of bovine trypsin (even frames of crystal x33) 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Ahlberg Gagner, V, Lundholm, I, Garcia-Bonete, M.J, Rodilla, H, Friedman, R, Zhaunerchyk, V, Bourenkov, G, Schneider, T, Stake, J, Katona, G. 登録日 2019-09-19 公開日 2020-01-22 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Clustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties. Sci Rep, 9, 2019

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