2TRM

THE THREE-DIMENSIONAL STRUCTURE OF ASN102 MUTANT OF TRYPSIN. ROLE OF ASP102 IN SERINE PROTEASE CATALYSIS

Summary for 2TRM

• Entry DOI: 10.2210/pdb2trm/pdb
• Descriptor: TRYPSIN, CALCIUM ION, BENZAMIDINE, ... (4 entities in total)
• Functional Keywords: hydrolase (serine proteinase)
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Secreted, extracellular space: P00763
• Total number of polymer chains: 1
• Total formula weight: 23974.08

Authors

Stroud, R.M.,Finer-Moore, J. (deposition date: 1988-04-25, release date: 1988-07-16, Last modification date: 2017-11-29)

• Primary citation: Sprang, S.,Standing, T.,Fletterick, R.J.,Stroud, R.M.,Finer-Moore, J.,Xuong, N.H.,Hamlin, R.,Rutter, W.J.,Craik, C.S.; The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.; Science, 237:905-909, 1987; PubMed: 3112942

Experimental method

X-RAY DIFFRACTION (2.8 Å)