PDB: 1133 件ウェブページステータス検索Chemie searchBIRD

---

6HXI	Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A 分子名称: ACETATE ION, CITRATE ANION, COENZYME A, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
4C6X	Crystal structure of M. tuberculosis C171Q KasA in complex with thiolactomycin (TLM) 分子名称: (2R)-2-(hexadecanoyloxy)-3-{[(10R)-10-methyloctadecanoyl]oxy}propyl phosphate, 1,2-ETHANEDIOL, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, ... 著者 Schiebel, J, Kapilashrami, K, Fekete, A, Bommineni, G.R, Schaefer, C.M, Mueller, M.J, Tonge, P.J, Kisker, C. 登録日 2013-09-19 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for the Recognition of Mycolic Acid Precursors by Kasa, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis J.Biol.Chem., 288, 2013
4C6W	Crystal structure of M. tuberculosis C171Q KasA 分子名称: (2R)-2-(hexadecanoyloxy)-3-{[(10R)-10-methyloctadecanoyl]oxy}propyl phosphate, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Schiebel, J, Kapilashrami, K, Fekete, A, Bommineni, G.R, Schaefer, C.M, Mueller, M.J, Tonge, P.J, Kisker, C. 登録日 2013-09-19 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis for the Recognition of Mycolic Acid Precursors by Kasa, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis J.Biol.Chem., 288, 2013
3DBM	Crystal Structure of Allene oxide synthase 分子名称: (9E,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE 著者 Li, L, Wang, X. 登録日 2008-06-01 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase. Proc.Natl.Acad.Sci.Usa, 105, 2008
1OXH	The crystal structure of beta-ketoacyl-[acyl carrier protein] synthase II from Streptococcus Pneumoniae, Triclinic form 分子名称: Beta ketoacyl-acyl carrier protein synthase, MAGNESIUM ION 著者 Price, A.C, Rock, C.O, White, S.W. 登録日 2003-04-02 公開日 2003-04-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The 1.3-Angstrom-Resolution Crystal Structure of beta-Ketoacyl-Acyl Carrier Protein Synthase II from Streptococcus pneumoniae. J.Bacteriol., 185, 2003
1TED	Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis 分子名称: MYRISTIC ACID, pks18 著者 Sankaranarayanan, R, Shanmugam, V.M, Rukmini, R. 登録日 2004-05-25 公開日 2004-08-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites Nat.Struct.Mol.Biol., 11, 2004
1OX0	The crystal structure of beta-ketoacyl-[acyl carrier protein] synthase II from Streptococcus pneumoniae 分子名称: Beta ketoacyl-acyl carrier protein synthase, MAGNESIUM ION 著者 Price, A.C, Rock, C.O, White, S.W. 登録日 2003-03-31 公開日 2003-04-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The 1.3-Angstrom-Resolution Crystal Structure of beta-Ketoacyl-Acyl Carrier Protein Synthase II from Streptococcus pneumoniae. J.Bacteriol., 185, 2003
4J7T	Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis 分子名称: D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ... 著者 Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2013-02-14 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
4J7Y	Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis 分子名称: D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ... 著者 Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2013-02-14 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
2K0X	The actinorhodin holo acyl carrier protein from S. coelicolor 分子名称: 4'-PHOSPHOPANTETHEINE, Actinorhodin polyketide synthase acyl carrier protein 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2008-02-15 公開日 2008-09-16 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein. Chembiochem, 9, 2008
2K0Y	The actinorhodin apo acyl carrier protein from S. coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein 著者 Crump, M.P, Evans, S.E, Christopher, W. 登録日 2008-02-15 公開日 2008-09-16 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein. Chembiochem, 9, 2008
3NE1	Mycobacterium tuberculosis Acyl Carrier Protein Synthase in complex with sulfate ion 分子名称: Holo-[acyl-carrier-protein] synthase, SULFATE ION 著者 Gokulan, K. 登録日 2010-06-08 公開日 2010-07-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Acta Crystallogr.,Sect.D, 67, 2011
3NE3	Mycobacterium tuberculosis Acyl Carrier Protein Synthase Apo structure 分子名称: Holo-[acyl-carrier-protein] synthase 著者 Gokulan, K, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2010-06-08 公開日 2010-07-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Acta Crystallogr.,Sect.D, 67, 2011
8GSA	Solution structure of holo acyl carrier protein A from Enterococcus faecalis 分子名称: Acyl carrier protein 著者 Yeon, J, Kim, Y. 登録日 2022-09-05 公開日 2023-03-29 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Structural study of acyl carrier protein of Enterococcus faecalis and its interaction with enzymes in de novo fatty acid synthesis. Biochem.Biophys.Res.Commun., 637, 2022
1E5M	Beta ketoacyl acyl carrier protein synthase II (KASII) from Synechocystis sp. 分子名称: BETA KETOACYL ACYL CARRIER PROTEIN SYNTHASE II 著者 Moche, M, Edwards, P, Dehesh, K, Lindqvist, Y. 登録日 2000-07-27 公開日 2001-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 The Crystal Structure of Beta-Ketoacyl-Acyl Carrier Protein Synthase II from Synechocystis Sp. At 1.54 A Resolution and its Relationship to Other Condensing Enzymes J.Mol.Biol., 305, 2001
3TZW	Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the orthorhombic apoform at 2.6 A 分子名称: 1,2-ETHANEDIOL, 12-mer peptide, Polyketide synthase PKS13, ... 著者 Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. 登録日 2011-09-28 公開日 2012-08-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
5CC5	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-3-carboxylic acid 分子名称: 1H-INDOLE-3-CARBOXYLIC ACID, GLYOXYLIC ACID, MAGNESIUM ION, ... 著者 Huang, H.-L, Sacchettini, J.C. 登録日 2015-07-01 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs To Be Published
5CC6	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-5-carboxylic acid 分子名称: 1H-indole-5-carboxylic acid, MAGNESIUM ION, Malate synthase G 著者 Huang, H.-L, Sacchettini, J.C. 登録日 2015-07-01 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs To Be Published
5CC3	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6-bromo-1H-indole-2-carboxylic acid 分子名称: 6-bromanyl-1H-indole-2-carboxylic acid, MAGNESIUM ION, Malate synthase G 著者 Huang, H.-L, Sacchettini, J.C. 登録日 2015-07-01 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs To Be Published
5CC7	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-6-carboxylic acid 分子名称: 1H-indole-6-carboxylic acid, MAGNESIUM ION, Malate synthase G 著者 Huang, H.-L, Sacchettini, J.C. 登録日 2015-07-01 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs To Be Published
1DV5	TERTIARY STRUCTURE OF APO-D-ALANYL CARRIER PROTEIN 分子名称: APO-D-ALANYL CARRIER PROTEIN 著者 Volkman, B.F, Zhang, Q, Debabov, D.V, Rivera, E, Kresheck, G.C, Neuhaus, F.C. 登録日 2000-01-19 公開日 2001-08-01 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Biosynthesis of D-alanyl-lipoteichoic acid: the tertiary structure of apo-D-alanyl carrier protein. Biochemistry, 40, 2001
5IKQ	The Structure of Meclofenamic Acid Bound to Human Cyclooxygenase-2 分子名称: 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, ... 著者 Orlando, B.J, Malkowski, M.G. 登録日 2016-03-03 公開日 2016-05-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
5IKV	The Structure of Flufenamic Acid Bound to Human Cyclooxygenase-2 分子名称: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... 著者 Orlando, B.J, Malkowski, M.G. 登録日 2016-03-03 公開日 2016-05-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.508 Å) 主引用文献 Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
5IKR	The Structure of Mefenamic Acid Bound to Human Cyclooxygenase-2 分子名称: 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... 著者 Orlando, B.J, Malkowski, M.G. 登録日 2016-03-03 公開日 2016-05-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.342 Å) 主引用文献 Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
2UUH	Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione 分子名称: DODECYL-ALPHA-D-MALTOSIDE, GLUTATHIONE, LEUKOTRIENE C4 SYNTHASE, ... 著者 Martinez Molina, D, Wetterholm, A, Kohl, A, McCarthy, A.A, Niegowski, D, Ohlson, E, Hammarberg, T, Eshaghi, S, Haeggstrom, J.Z, Nordlund, P. 登録日 2007-03-02 公開日 2007-07-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase. Nature, 448, 2007

<45678910111213141516171819>