6RTA
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5AC2
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![BU of 5ac2 by Molmil](/molmil-images/mine/5ac2) | human aldehyde dehydrogenase 1A1 with duocarmycin analog | 分子名称: | 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, RETINAL DEHYDROGENASE 1, YTTERBIUM (III) ION, ... | 著者 | Koch, M.F, Harteis, S, Blank, I.D, Pestel, G, Tietze, L.F, Ochsenfeld, C, Schneider, S, Sieber, S.A. | 登録日 | 2015-08-11 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues. Angew.Chem.Int.Ed.Engl., 54, 2015
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6RTO
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![BU of 6rto by Molmil](/molmil-images/mine/6rto) | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 4 hours of soaking | 分子名称: | 1-methylidenenaphthalen-2-one, FLAVIN-ADENINE DINUCLEOTIDE, TRIETHYLENE GLYCOL, ... | 著者 | Angelucci, F, Silvestri, I, Fata, F, Williams, D.L. | 登録日 | 2019-05-24 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med, 147, 2020
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2MMZ
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![BU of 2mmz by Molmil](/molmil-images/mine/2mmz) | Solution structure of the apo form of human glutaredoxin 5 | 分子名称: | Glutaredoxin-related protein 5, mitochondrial | 著者 | Banci, L, Brancaccio, D, Ciofi-Baffoni, S, Del Conte, R, Gadepalli, R, Mikolajczyk, M, Neri, S, Piccioli, M, Winkelmann, J. | 登録日 | 2014-03-25 | 公開日 | 2014-04-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | [2Fe-2S] cluster transfer in iron-sulfur protein biogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
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4ZVW
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2Z8V
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![BU of 2z8v by Molmil](/molmil-images/mine/2z8v) | Structure of an IgNAR-AMA1 complex | 分子名称: | Apical membrane antigen 1, New antigen receptor variable domain | 著者 | Streltsov, V.A, Henderson, K.A, Batchelor, A.H, Coley, A.M, Nuttall, S.D. | 登録日 | 2007-09-11 | 公開日 | 2007-11-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition Structure, 15, 2007
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5AEC
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![BU of 5aec by Molmil](/molmil-images/mine/5aec) | Type II Baeyer-Villiger monooxygenase.The oxygenating constituent of 3,6-diketocamphane monooxygenase from CAM plasmid of Pseudomonas putida in complex with FMN. | 分子名称: | 3,6-DIKETOCAMPHANE 1,6 MONOOXYGENASE, CHLORIDE ION, GLYCEROL, ... | 著者 | Isupov, M.N, Schroeder, E, Gibson, R.P, Beecher, J, Donadio, G, Saneei, V, Dcunha, S, McGhie, E.J, Sayer, C, Davenport, C.F, Lau, P.C, Hasegawa, Y, Iwaki, H, Kadow, M, Loschinski, K, Bornscheuer, U.T, Bourenkov, G, Littlechild, J.A. | 登録日 | 2015-08-28 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The Oxygenating Constituent of 3,6-Diketocamphane Monooxygenase from the Cam Plasmid of Pseudomonas Putida: The First Crystal Structure of a Type II Baeyer-Villiger Monooxygenase. Acta Crystallogr.,Sect.D, 71, 2015
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5XJG
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![BU of 5xjg by Molmil](/molmil-images/mine/5xjg) | Crystal structure of Vac8p bound to Nvj1p | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Nucleus-vacuole junction protein 1, ... | 著者 | Jeong, H, Park, J, Jun, Y, Lee, C. | 登録日 | 2017-05-01 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2IN0
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![BU of 2in0 by Molmil](/molmil-images/mine/2in0) | crystal structure of Mtu recA intein splicing domain | 分子名称: | Endonuclease PI-MtuI | 著者 | Van Roey, P. | 登録日 | 2006-10-05 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic and mutational studies of Mycobacterium tuberculosis recA mini-inteins suggest a pivotal role for a highly conserved aspartate residue. J.Mol.Biol., 367, 2007
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6IQS
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2MM8
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![BU of 2mm8 by Molmil](/molmil-images/mine/2mm8) | Structural and biochemical characterization of Jaburetox | 分子名称: | Urease | 著者 | Dobrovolska, O, Lopez, F, Ciurli, S, Zambelli, B, Carlini, C. | 登録日 | 2014-03-12 | 公開日 | 2015-01-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | 1H, 13C, 15N resonance assignments of reduced Jaburetox To be Published
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6RY7
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6RRJ
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![BU of 6rrj by Molmil](/molmil-images/mine/6rrj) | GOLGI ALPHA-MANNOSIDASE II in complex with 5-(Adamantan-1yl-methoxy)-pentyl 2,5-dideoxy-2,5-imino-D-talo-hexonamide | 分子名称: | (2~{S},3~{R},4~{S},5~{R})-~{N}-[5-(1-adamantylmethoxy)pentyl]-5-(hydroxymethyl)-3,4-bis(oxidanyl)pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, Alpha-mannosidase 2, ... | 著者 | Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, van Rijssel, E.R, Debets, M, Geurink, P.P, Ovaa, H, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J. | 登録日 | 2019-05-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. J.Am.Chem.Soc., 142, 2020
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7AK6
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![BU of 7ak6 by Molmil](/molmil-images/mine/7ak6) | Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | 登録日 | 2020-09-29 | 公開日 | 2021-02-03 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
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2MEF
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![BU of 2mef by Molmil](/molmil-images/mine/2mef) | CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | 分子名称: | LYSOZYME, SODIUM ION | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | 登録日 | 1998-05-04 | 公開日 | 1998-07-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme Protein Eng., 12, 1999
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6RRU
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![BU of 6rru by Molmil](/molmil-images/mine/6rru) | GOLGI ALPHA-MANNOSIDASE II in complex with (5R,6R,7S,8S)-5,6,7,8-tetrahydro-5-(hydroxymethyl)-3-(3-phenylpropyl)imidazo[1,2-a]pyridine-6,7,8-triol | 分子名称: | (5~{R},6~{R},7~{S},8~{S})-5-(hydroxymethyl)-2-(3-phenylpropyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-6,7,8-triol, Alpha-mannosidase 2, ZINC ION | 著者 | Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, van Rijssel, E.R, Debets, M, Geurink, P.P, Ovaa, H, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J. | 登録日 | 2019-05-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. J.Am.Chem.Soc., 142, 2020
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5AC0
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![BU of 5ac0 by Molmil](/molmil-images/mine/5ac0) | ovis aries Aldehyde Dehydrogenase 1A1 in complex with a duocarmycin analog | 分子名称: | 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Koch, M.F, Harteis, S, Blank, I.D, Pestel, G, Tietze, L.F, Ochsenfeld, C, Schneider, S, Sieber, S.A. | 登録日 | 2015-08-10 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues. Angew.Chem.Int.Ed.Engl., 54, 2015
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2ZOY
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![BU of 2zoy by Molmil](/molmil-images/mine/2zoy) | The multi-drug binding transcriptional repressor CgmR (CGL2612 protein) from C.glutamicum | 分子名称: | GLYCEROL, Transcriptional regulator | 著者 | Itou, H, Yao, M, Watanabe, N, Tanaka, I. | 登録日 | 2008-06-20 | 公開日 | 2008-07-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The CGL2612 protein from Corynebacterium glutamicum is a drug resistance-related transcriptional repressor: structural and functional analysis of a newly identified transcription factor from genomic DNA analysis J.Biol.Chem., 280, 2005
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5XMZ
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![BU of 5xmz by Molmil](/molmil-images/mine/5xmz) | Verticillium effector PevD1 | 分子名称: | CALCIUM ION, CHLORIDE ION, Effector protein PevD1 | 著者 | Liu, X, Zhou, R. | 登録日 | 2017-05-17 | 公開日 | 2017-07-05 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2 J. Exp. Bot., 68, 2017
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5A9S
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![BU of 5a9s by Molmil](/molmil-images/mine/5a9s) | NADPH complex of Imine Reductase from Amycolatopsis orientalis | 分子名称: | CALCIUM ION, IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2015-07-22 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis Acs Catalysis, 6, 2016
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6S0O
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![BU of 6s0o by Molmil](/molmil-images/mine/6s0o) | Crystal Structure of Two-Domain Laccase from Streptomyces griseoflavus produced at 0.25 mM copper sulfate in growth medium | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, GLYCEROL, ... | 著者 | Gabdulkhakov, A.G, Tishchenko, T.V, Kolyadenko, I.A. | 登録日 | 2019-06-17 | 公開日 | 2019-07-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase fromStreptomyces griseoflavusAc-993. Int J Mol Sci, 20, 2019
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6RT9
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7AOA
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![BU of 7aoa by Molmil](/molmil-images/mine/7aoa) | Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex | 分子名称: | Histone deacetylase 1, Histone-binding protein RBBP4, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. | 登録日 | 2020-10-14 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (19.4 Å) | 主引用文献 | The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
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6RTJ
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![BU of 6rtj by Molmil](/molmil-images/mine/6rtj) | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 1 hour of soaking | 分子名称: | 1-[(dimethylamino)methyl]naphthalen-2-ol, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Angelucci, F, Silvestri, I, Fata, F, Williams, D.L. | 登録日 | 2019-05-24 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med, 147, 2020
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6RTU
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![BU of 6rtu by Molmil](/molmil-images/mine/6rtu) | Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with alpha-aminoadipic acid | 分子名称: | 2-AMINOHEXANEDIOIC ACID, ACETATE ION, GLYCEROL, ... | 著者 | Hasse, D, Huelsemann, J, Carlsson, G, Andersson, I. | 登録日 | 2019-05-26 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus. Acta Crystallogr D Struct Biol, 75, 2019
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