6RTJ
Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 1 hour of soaking
Summary for 6RTJ
Entry DOI | 10.2210/pdb6rtj/pdb |
Descriptor | Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | fragment, secondary site, schistosomiasis, fad/nad linked reductase, flavoprotein, time-resolved structural studies |
Biological source | Schistosoma mansoni |
Total number of polymer chains | 1 |
Total formula weight | 66479.33 |
Authors | Angelucci, F.,Silvestri, I.,Fata, F.,Williams, D.L. (deposition date: 2019-05-24, release date: 2020-01-08, Last modification date: 2024-10-09) |
Primary citation | Silvestri, I.,Lyu, H.,Fata, F.,Banta, P.R.,Mattei, B.,Ippoliti, R.,Bellelli, A.,Pitari, G.,Ardini, M.,Petukhova, V.,Thatcher, G.R.J.,Petukhov, P.A.,Williams, D.L.,Angelucci, F. Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med, 147:200-211, 2020 Cited by PubMed: 31870799DOI: 10.1016/j.freeradbiomed.2019.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report