7KNQ
 
 | | SARM1 Octamer | | 分子名称: | NAD(+) hydrolase SARM1 | | 著者 | Shen, C, Wu, H. | | 登録日 | 2020-11-05 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Multiple domain interfaces mediate SARM1 autoinhibition.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7QOR
 | | Structure of beta-lactamase TEM-171 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | 著者 | Hakanpaa, J, Petrova, T, Samygina, V.R, Chojnowski, G, Lamzin, V, Egorov, A.M. | | 登録日 | 2021-12-28 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Crystal structures of the molecular class A beta-lactamase TEM-171 and its complexes with tazobactam.
Acta Crystallogr D Struct Biol, 78, 2022
|
|
8V6K
 | |
7QI8
 | | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE AND INHIBITOR | | 分子名称: | 2-azanyl-6-[(1~{S},7~{S})-2,2-bis(fluoranyl)-7-oxidanyl-cycloheptyl]-4-methoxy-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one, LYSINE, Lysine--tRNA ligase 1 | | 著者 | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | | 登録日 | 2021-12-14 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.
Nat Commun, 13, 2022
|
|
5F9E
 | | Structure of Protein Kinase C theta with compound 10: 2,2-dimethyl-7-(2-oxidanylidene-3~{H}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{H}-quinazolin-4-one | | 分子名称: | 2,2-dimethyl-7-(2-oxidanylidene-3~{H}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{H}-quinazolin-4-one, Protein kinase C theta type | | 著者 | Klein, M. | | 登録日 | 2015-12-09 | | 公開日 | 2016-05-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKC theta inhibitors.
Bioorg.Med.Chem., 24, 2016
|
|
2Y9P
 | | Pex4p-Pex22p mutant II structure | | 分子名称: | PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | | 著者 | Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M. | | 登録日 | 2011-02-16 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Pex4P-Pex22P Structure
To be Published
|
|
4MRF
 | | Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule | | 分子名称: | 1,2,3,4-tetrahydroisoquinoline, CD44 antigen, DIMETHYL SULFOXIDE, ... | | 著者 | Liu, L.K, Finzel, B. | | 登録日 | 2013-09-17 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors.
J.Med.Chem., 57, 2014
|
|
1NM5
 | | R. rubrum transhydrogenase (dI.Q132N)2(dIII)1 asymmetric complex | | 分子名称: | GLYCEROL, NAD(P) transhydrogenase subunit alpha part 1, NAD(P) transhydrogenase subunit beta, ... | | 著者 | Van Boxel, G.I, Quirk, P.G, Cotton, N.P, White, S.A, Jackson, J.B. | | 登録日 | 2003-01-09 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.
Biochemistry, 42, 2003
|
|
8UD3
 | | SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form | | 分子名称: | Non-structural protein 15, RNA (35-MER) | | 著者 | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | | 登録日 | 2023-09-28 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.
Protein Cell, 15, 2024
|
|
1NO1
 | | Structure of truncated variant of B.subtilis SPP1 phage G39P helicase loader/inhibitor protein | | 分子名称: | replisome organizer | | 著者 | Bailey, S, Sedelnikova, S.E, Mesa, P, Ayora, S, Waltho, J.P, Ashcroft, A.E, Baron, A.J, Alonso, J.C, Rafferty, J.B. | | 登録日 | 2003-01-15 | | 公開日 | 2003-05-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P
J.Biol.Chem., 278, 2003
|
|
8V6O
 | | Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, SODIUM ION, ... | | 著者 | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | | 登録日 | 2023-12-01 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
|
|
2W4U
 | | Isometrically contracting insect asynchronous flight muscle quick frozen after a length step | | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ... | | 著者 | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | 登録日 | 2008-12-02 | | 公開日 | 2010-08-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
|
|
4FFE
 | | The structure of cowpox virus CPXV018 (OMCP) | | 分子名称: | CPXV018 protein | | 著者 | Lazear, E, Peterson, L.W, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-06-01 | | 公開日 | 2012-06-20 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of the Cowpox Virus-Encoded NKG2D Ligand OMCP.
J.Virol., 87, 2013
|
|
8V6N
 | | Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, ARACHIDONIC ACID, ... | | 著者 | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | | 登録日 | 2023-12-01 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
|
|
2YBN
 | |
5FBL
 | | PI4KB in complex with Rab11 and the MI356 Inhibitor | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.372 Å) | | 主引用文献 | PI4KB in complex with Rab11 and the MI356 Inhibitor
To Be Published
|
|
4NBD
 | | Carbazole-bound oxygenase with Phe275 replaced by Trp and ferredoxin complex of carbazole 1,9a-dioxygenase (form2) | | 分子名称: | 9H-CARBAZOLE, FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Ashikawa, Y, Usami, Y, Inoue, K, Nojiri, H. | | 登録日 | 2013-10-23 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis of the divergent oxygenation reactions catalyzed by the rieske nonheme iron oxygenase carbazole 1,9a-dioxygenase.
Appl.Environ.Microbiol., 80, 2014
|
|
1NPP
 | | CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN P2(1) | | 分子名称: | ISOPROPYL ALCOHOL, Transcription antitermination protein nusG | | 著者 | Knowlton, J.R, Bubunenko, M, Andrykovitch, M, Guo, W, Routzahn, K.M, Waugh, D.S, Court, D.L, Ji, X. | | 登録日 | 2003-01-18 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by
Site-Directed Mutants
Biochemistry, 42, 2003
|
|
5FBV
 | | PI4KB in complex with Rab11 and the MI364 Inhibitor | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.285 Å) | | 主引用文献 | PI4KB in complex with Rab11 and the MI364 Inhibitor
To Be Published
|
|
2W1X
 | | The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data | | 分子名称: | CHLORIDE ION, LYSOZYME C, SODIUM ION | | 著者 | Cianci, M, Helliwell, J.R, Suzuki, A. | | 登録日 | 2008-10-21 | | 公開日 | 2008-11-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Interdependence of Wavelength, Redundancy and Dose in Sulfur Sad Experiments.
Acta Crystallogr.,Sect.D, 64, 2008
|
|
7QH0
 | |
2YC0
 | | FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLUTARATE | | 分子名称: | (2R)-2-hydroxypentanedioic acid, FE (II) ION, GLYCEROL, ... | | 著者 | Chowdhury, R, Clifton, I.J, Schofield, C.J. | | 登録日 | 2011-03-10 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
EMBO Rep., 12, 2011
|
|
1NR0
 | | Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans Homologue Of Yeast Actin Interacting Protein 1 (AIP1). | | 分子名称: | Actin interacting protein 1, MANGANESE (II) ION | | 著者 | Vorobiev, S.M, Mohri, K, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2003-01-23 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of Functional Residues on Caenorhabditis elegans Actin-interacting Protein 1 (UNC-78) for Disassembly of Actin Depolymerizing Factor/Cofilin-bound Actin Filaments
J.Biol.Chem., 279, 2004
|
|
8UBG
 | | DpHF19 filament | | 分子名称: | DpHF19,Green fluorescent protein (Fragment) | | 著者 | Lynch, E.M, Shen, H, Kollman, J.M, Baker, D. | | 登録日 | 2023-09-22 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | De novo design of pH-responsive self-assembling helical protein filaments.
Nat Nanotechnol, 19, 2024
|
|
4FGQ
 | | Legionella pneumophila LapG | | 分子名称: | Periplasmic protein | | 著者 | Chatterjee, D, Boyd, C.D, O'Toole, G.A, Sondermann, H. | | 登録日 | 2012-06-04 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.645 Å) | | 主引用文献 | Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila.
J.Bacteriol., 194, 2012
|
|
