6T1E
| Streptavidin variants harbouring an artificial organocatalyst based cofactor | 分子名称: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, ACETATE ION, CHLORIDE ION, ... | 著者 | Lechner, H, Hocker, B. | 登録日 | 2019-10-04 | 公開日 | 2020-10-14 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
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6XB4
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6XMX
| Cryo-EM structure of BCL6 bound to BI-3802 | 分子名称: | 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide, B-cell lymphoma 6 protein | 著者 | Yoon, H, Burman, S.S.R, Hunkeler, M, Nowak, R.P, Fischer, E.S. | 登録日 | 2020-07-01 | 公開日 | 2020-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Small-molecule-induced polymerization triggers degradation of BCL6. Nature, 588, 2020
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6XPG
| Crystal Structure of Sialate O-acetylesterase from Bacteroides vulgatus by Serial Crystallography | 分子名称: | Lysophospholipase L1 | 著者 | Kim, Y, Sherrell, D.A, Owen, R, Axford, D, Ebrahim, A, Johnson, J, Welk, L, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2020-07-08 | 公開日 | 2020-07-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Sialate O-acetylesterase from Bacteroides vulgatus by Serial Crystallography To Be Published
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6XY2
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7LAS
| Cryo-EM structure of PCV2 Replicase bound to ssDNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*A)-3'), ... | 著者 | Khayat, R. | 登録日 | 2021-01-06 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
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7LAR
| Cryo-EM structure of PCV2 Replicase bound to ssDNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | 著者 | Khayat, R. | 登録日 | 2021-01-06 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
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5W5Y
| RNA polymerase I Initial Transcribing Complex | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Han, Y, He, Y. | 登録日 | 2017-06-16 | 公開日 | 2017-07-26 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
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6XQU
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5W66
| RNA polymerase I Initial Transcribing Complex State 3 | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Han, Y, He, Y. | 登録日 | 2017-06-16 | 公開日 | 2017-07-26 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
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6XHU
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6SXX
| Crystal structure of the bromodomain of human CREBBP in complex with ACA007 | 分子名称: | (3~{R})-1-ethanoylpyrrolidine-3-carboxylic acid, 1,2-ETHANEDIOL, CREBBP | 著者 | Xiang, W, Bedi, R.K, Sledz, P, Caflisch, A. | 登録日 | 2019-09-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of the bromodomain of human CREBBP in complex with ACA007 To Be Published
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6XWB
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6XIP
| The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 | 分子名称: | 1,2-ETHANEDIOL, Non-structural protein 7, Non-structural protein 8 | 著者 | Wilamowski, M, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-06-20 | 公開日 | 2020-07-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication. Biophys.J., 120, 2021
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5VOI
| X-ray crystal structure of bacterial RNA polymerase and pyrG promoter complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. | 登録日 | 2017-05-02 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6XJF
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6XK9
| Cereblon in complex with DDB1, CC-90009, and GSPT1 | 分子名称: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | 著者 | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | 登録日 | 2020-06-25 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells. Blood, 137, 2021
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5VYA
| S. cerevisiae Hsp104:casein complex, Extended Conformation | 分子名称: | Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | 登録日 | 2017-05-24 | 公開日 | 2017-07-05 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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6XPM
| Crystal Structure of Sialate O-acetylesterase from Bacteroides vulgatus with microfluidics crystals at room temperature | 分子名称: | Lysophospholipase L1, SODIUM ION | 著者 | Kim, Y, Johnson, J, Welk, L, Endres, M, Levens, A, Sherrell, D.A, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2020-07-08 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Sialate O-acetylesterase from Bacteroides vulgatus with microfluidics crystals at room temperature To Be Published
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6NAD
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5VSM
| Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine | 分子名称: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | 著者 | Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. | 登録日 | 2017-05-11 | 公開日 | 2017-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural studies of viperin, an antiviral radical SAM enzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6X6S
| Cryo-EM Structure of the Helicobacter pylori OMC | 分子名称: | Cag pathogenicity island protein (Cag7), Type IV secretion system apparatus protein Cag3, Type IV secretion system apparatus protein CagM, ... | 著者 | Sheedlo, M.J, Chung, J.M, Sawhney, N, Durie, C.L, Cover, T.L, Ohi, M.D, Lacy, D.B. | 登録日 | 2020-05-29 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex. Elife, 9, 2020
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6SL5
| Dunaliella Photosystem I Supercomplex | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | 著者 | Nelson, N, Caspy, I, Malavath, T, Klaiman, D, Shkolinsky, Y. | 登録日 | 2019-08-18 | 公開日 | 2020-06-24 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Structure and energy transfer pathways of the Dunaliella Salina photosystem I supercomplex. Biochim Biophys Acta Bioenerg, 1861, 2020
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6Y9A
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6YA8
| Cdc7-Dbf4 bound to ADP-BeF3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, ... | 著者 | Dick, S.D, Cherepanov, P. | 登録日 | 2020-03-11 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase. Structure, 28, 2020
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