3D6P
 
 | | RNase A- 5'-Deoxy-5'-N-morpholinouridine complex | | 分子名称: | 1-(5-deoxy-5-morpholin-4-yl-alpha-L-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Zogrpahos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-05-20 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation.
J.Med.Chem., 52, 2009
|
|
3X1O
 | | Crystal structure of the ROQ domain of human Roquin | | 分子名称: | IODIDE ION, Roquin-1 | | 著者 | Ose, T, Verma, A, Cockburn, J.B, Berrow, N.S, Alderton, D, Stuart, D, Owens, R.J, Jones, E.Y. | | 登録日 | 2014-11-26 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis
Nat Commun, 6, 2015
|
|
3D6Q
 | | The RNase A- 5'-Deoxy-5'-N-piperidinouridine complex | | 分子名称: | 1-(5-deoxy-5-piperidin-1-yl-alpha-L-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione, CITRATE ANION, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-05-20 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation.
J.Med.Chem., 52, 2009
|
|
8CIH
 | | Structure of FL CINP | | 分子名称: | Cyclin-dependent kinase 2-interacting protein, SODIUM ION | | 著者 | Foglizzo, M, Zeqiraj, E. | | 登録日 | 2023-02-09 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity.
Cell, 187, 2024
|
|
4DOL
 | |
8CU0
 | | 12-mer DNA structure of ExBIM bound to RNaseH -modified DDD | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*(OWR)P*CP*CP*G)-3'), GLYCEROL, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
|
|
8CTY
 | | 12-mer DNA structure of ExBIM bound to RNase-H | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
|
|
8CTZ
 | | 12-mer DNA structure of ExBIM & O6Me-G bound to RNase-H | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*CP*GP*CP*(6OG)P*AP*AP*TP*TP*(OWR)P*GP*CP*G)-3'), ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
|
|
9HDM
 | | Crystal structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) from Neurospora crassa in complex with thymidine | | 分子名称: | (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Friedrich, F, Genz, F, Einsle, O, Mueller, M, Fessner, N.D. | | 登録日 | 2024-11-12 | | 公開日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification and Characterization of Pyrimidine Nucleoside 2'-Hydroxylase
Acs Catalysis, 2025
|
|
9HDL
 | | Crystal structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) from Neurospora crassa | | 分子名称: | Clavaminate synthase-like protein, FE (III) ION | | 著者 | Friedrich, F, Genz, F, Einsle, O, Mueller, M, Fessner, N.D. | | 登録日 | 2024-11-12 | | 公開日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Identification and Characterization of Pyrimidine Nucleoside 2'-Hydroxylase
Acs Catalysis, 2025
|
|
8CXR
 | | Crystal structure of MraY bound to a sphaerimicin analogue | | 分子名称: | (1S,4R,5S,6R,7S,9S,10S,11S,13S,14R)-9-[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]-14-(hexadecanoyloxy)-5,6,13-trihydroxy-8,16-dioxa-2,11-diazatricyclo[9.3.1.1~4,7~]hexadecane-10-carboxylic acid, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Mashalidis, E.H, Lee, S.Y. | | 登録日 | 2022-05-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY.
Nat Commun, 13, 2022
|
|
4H7W
 | |
3D6O
 | | The RNase A- 5'-Deoxy-5'-N-(ethyl isonipecotatyl)uridine complex | | 分子名称: | 1-{5-deoxy-5-[4-(ethoxycarbonyl)piperidin-1-yl]-alpha-L-arabinofuranosyl}pyrimidine-2,4(1H,3H)-dione, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-05-20 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation.
J.Med.Chem., 52, 2009
|
|
4DOK
 | |
4DOO
 | | Crystal structure of Arabidopsis thaliana fatty-acid binding protein At3g63170 (AtFAP1) | | 分子名称: | Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION | | 著者 | Noel, J.P, Pojer, F, Louie, G.V, Bowman, M.E. | | 登録日 | 2012-02-09 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
|
|
3GAE
 | | Crystal Structure of PUL | | 分子名称: | CHLORIDE ION, GLYCEROL, Protein DOA1 | | 著者 | Zhao, G, Schindelin, H, Lennarz, W.J. | | 登録日 | 2009-02-17 | | 公開日 | 2009-12-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
1Y1P
 | | X-ray structure of aldehyde reductase with NADPH | | 分子名称: | ACETATE ION, ADENOSINE MONOPHOSPHATE, Aldehyde reductase II, ... | | 著者 | Kamitori, S, Kita, K. | | 登録日 | 2004-11-19 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds
J.Mol.Biol., 352, 2005
|
|
4ZWU
 | | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F, V342L, I215Y | | 分子名称: | BARIUM ION, GLYCEROL, GLYCOLIC ACID, ... | | 著者 | Daczkowski, C.M, Pegan, S.D, Harvey, S.P. | | 登録日 | 2015-05-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Engineering the Organophosphorus Acid Anhydrolase Enzyme for Increased Catalytic Efficiency and Broadened Stereospecificity on Russian VX.
Biochemistry, 54, 2015
|
|
9C9Z
 | | S.c INO80 in complex with Xenopus 0/80 nucleosome, INO80 Core | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | | 著者 | Wu, H, Kaur, U, Narlikar, G.J, Cheng, Y.F. | | 登録日 | 2024-06-16 | | 公開日 | 2025-07-16 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning
Science, 2025
|
|
9C9S
 | | S.c INO80 in complex with S.c 0/40 nucleosome, Class 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | | 著者 | Wu, H, Kaur, U, Narlikar, G.J, Cheng, Y.F. | | 登録日 | 2024-06-15 | | 公開日 | 2025-07-16 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning
Science, 2025
|
|
6SLO
 | | Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine | | 分子名称: | 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60 | | 著者 | Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M. | | 登録日 | 2019-08-20 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat Commun, 11, 2020
|
|
8RM5
 | | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2024-01-05 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
|
|
9H8L
 | | Crystal Structure of Polyphosphate kinase 2-II (PPK2-II) from Lysinibacillus fusiformis bound to TMP | | 分子名称: | PHOSPHATE ION, Polyphosphate kinase, THYMIDINE-5'-PHOSPHATE | | 著者 | Friedrich, F, Kuge, M, Keppler, M, Gerhardt, S, Einsle, O, Andexer, J.N. | | 登録日 | 2024-10-29 | | 公開日 | 2025-02-05 | | 最終更新日 | 2025-03-12 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Insights into Broad-Range Polyphosphate Kinase 2-II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis.
Chembiochem, 26, 2025
|
|
3OAK
 | |
9H8J
 | | Crystal Structure of Polyphosphate kinase 2-II (PPK2-II) from Lysinibacillus fusiformis in apo form | | 分子名称: | PHOSPHATE ION, Polyphosphate kinase, SUCCINIC ACID | | 著者 | Friedrich, F, Kuge, M, Keppler, M, Gerhardt, S, Einsle, O, Andexer, J.N. | | 登録日 | 2024-10-29 | | 公開日 | 2025-02-05 | | 最終更新日 | 2025-03-12 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Insights into Broad-Range Polyphosphate Kinase 2-II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis.
Chembiochem, 26, 2025
|
|
