PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7ARP	Native L-2-haloacid dehalogenase from Zobellia galactanivorans 分子名称: (S)-2-haloacid dehalogenase, PHOSPHATE ION, THIOCYANATE ION 著者 Grigorian, E, Roret, T, Czjzek, M, Leblanc, C, Delage, L. 登録日 2020-10-26 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 X-ray structure and mechanism of ZgHAD, a L-2-haloacid dehalogenase from the marine Flavobacterium Zobellia galactanivorans. Protein Sci., 2022
5N08	Structure of the apo form of the NO response regulator NsrR 分子名称: HTH-type transcriptional repressor NsrR 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2017-02-02 公開日 2017-04-26 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.90095472 Å) 主引用文献 Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding. Nat Commun, 8, 2017
7AJ0	Crystal structure of PsFucS1 sulfatase from Pseudoalteromonas sp. 分子名称: Arylsulfatase, CALCIUM ION, CHLORIDE ION 著者 Roret, T, Mikkelsen, M.D, Czjzek, M, Meyer, A.S. 登録日 2020-09-28 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A novel thermostable prokaryotic fucoidan active sulfatase PsFucS1 with an unusual quaternary hexameric structure. Sci Rep, 11, 2021
7B39	Allene-Based Design of a Noncalcemic Vitamin D Receptor Agonist 分子名称: (1R,3S,Z)-5-(2-((3aS,7aS,E)-1-(6-hydroxy-6-methylhept-1-en-1-ylidene)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... 著者 Rochel, N. 登録日 2020-11-29 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Design, Synthesis, Evaluation and Structure of Allenic 1 alpha ,25-Dihydroxyvitamin D 3 Analogs with Locked Mobility at C-17. Chemistry, 27, 2021
7B4J	Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, SUCCINIC ACID 著者 Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2020-12-02 公開日 2021-09-01 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines. Acs Catalysis, 11, 2021
5MZK	Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-[5-chloro-6-(cyclobutylmethoxy)-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl]propanoic acid 分子名称: 3-[5-chloro-6-(cyclobutylmethoxy)-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl]propanoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Rowland, P. 登録日 2017-01-31 公開日 2017-04-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis. J. Med. Chem., 60, 2017
7B4I	Thermostable omega transaminase PjTA-R6 variant W58G engineered for asymmetric synthesis of enantiopure bulky amines 分子名称: Aspartate aminotransferase family protein, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID 著者 Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. 登録日 2020-12-02 公開日 2021-09-01 最終更新日 2021-09-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines. Acs Catalysis, 11, 2021
6SXY	STRUCTURE OF S192A-ESTER-HYDROLASE EH3 FROM THE METAGENOME OF MARINE SEDIMENTS AT MILAZZO HARBOR (SICILY, ITALY) COMPLEXED WITH METHYL (2S)-2-PHENYLPROPANOATE 分子名称: DI(HYDROXYETHYL)ETHER, Esterase, GLYCEROL, ... 著者 Cea-Rama, I, Sanz-Aparicio, J. 登録日 2019-09-26 公開日 2021-04-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase. Comput Struct Biotechnol J, 19, 2021
5N2E	Structure of the E9 DNA polymerase from vaccinia virus 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Tarbouriech, N, Burmeister, W.P, Iseni, F. 登録日 2017-02-07 公開日 2017-11-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding. Nat Commun, 8, 2017
5MZW	Crystal structure of the decarboxylase AibA/AibB 分子名称: GLYCEROL, Glutaconate CoA-transferase family, subunit A, ... 著者 Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. 登録日 2017-02-02 公開日 2017-05-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
6SYA	STRUCTURE OF S192A-ESTER-HYDROLASE EH3 FROM THE METAGENOME OF MARINE SEDIMENTS AT MILAZZO HARBOR (SICILY, ITALY) COMPLEXED WITH METHYL (2R)-2-PHENYLPROPANOATE 分子名称: Esterase, GLYCEROL, methyl (2~{R})-2-phenylpropanoate 著者 Cea-Rama, I, Sanz-Aparicio, J. 登録日 2019-09-27 公開日 2021-04-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase. Comput Struct Biotechnol J, 19, 2021
5N07	Structure of the [4Fe-4S] form of the NO response regulator NsrR 分子名称: CHLORIDE ION, HTH-type transcriptional repressor NsrR, IRON/SULFUR CLUSTER, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2017-02-02 公開日 2017-04-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding. Nat Commun, 8, 2017
7AIL	Ribonucleotide Reductase R2m protein from Aquifex aeolicus 分子名称: FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta 著者 Rehling, D, Scaletti, E.R, Stenmark, P. 登録日 2020-09-27 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
5N0C	Crystal structure of the tetanus neurotoxin in complex with GM1a 分子名称: DI(HYDROXYETHYL)ETHER, Tetanus toxin, ZINC ION, ... 著者 Masuyer, G, Conrad, J, Stenmark, P. 登録日 2017-02-02 公開日 2017-06-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structure of the tetanus toxin reveals pH-mediated domain dynamics. EMBO Rep., 18, 2017
7AJ6	LN02 Fab 分子名称: LN02, LN02 heavy chain 著者 Caillat, C, Fenwick, G, Pantaleo, G, Weissenhorn, W. 登録日 2020-09-28 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 LN02 Fab To Be Published
7B15	14-3-3sigma in complex with SHN3pT869 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pT869 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
7B13	14-3-3sigma in complex with SHN3pS542 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pS542 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
7AHF	Dimeric structure of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S L114E varaiant 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Ubiquitin-conjugating enzyme E2 S 著者 Liess, A.K.L, Feiler, C.G, Lorenz, S. 登録日 2020-09-24 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural analyses of the ubiquitin-conjugating enzyme UBE2S in different crystal forms To Be Published
6SY8	Mopeia Virus Exonuclease domain fully depleted of Manganese un ALD compound 分子名称: Nucleoprotein, ZINC ION 著者 Nguyen, T.H.V, Ferron, F. 登録日 2019-09-27 公開日 2021-07-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate Iucrj, 2022
5N49	BRPF2 in complex with Compound 7 分子名称: 2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione, Bromodomain-containing protein 1 著者 Bouche, L, Christ, C.D, Siegel, S, Fernandez-Montalvan, A.E, Holton, S.J, Fedorov, O, ter Laak, A, Sugawara, T, Stoeckigt, D, Tallant, C, Bennett, J, Monteiro, O, Saez, L.D, Siejka, P, Meier, J, Puetter, V, Weiske, J, Mueller, S, Huber, K.V.M, Hartung, I.V, Haendler, B. 登録日 2017-02-10 公開日 2017-05-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. J. Med. Chem., 60, 2017
5N11	Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... 著者 Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G. 登録日 2017-02-04 公開日 2017-03-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity. Cell Host Microbe, 21, 2017
7AGJ	Ribonucleotide Reductase R1 protein from Aquifex aeolicus 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Rehling, D, Scaletti, E.R, Stenmark, P. 登録日 2020-09-22 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
7AFX	Crystal structure of the metallo-beta-lactamase VIM2 with 139 分子名称: 3-(2-chlorophenyl)-7-methyl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-2, FORMIC ACID, ... 著者 Brem, J, Schofield, C.J. 登録日 2020-09-21 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.636 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM2 with 139 To Be Published
7AHW	The crystal structure of gene product PA4063 from Pseudomonas aeruginosa 分子名称: Uncharacterized protein 著者 Fiorillo, A, Ilari, A. 登録日 2020-09-25 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa. Acta Crystallogr D Struct Biol, 77, 2021
5N21	Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand 分子名称: 2-[(2~{S})-1-[3-cyano-7-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidin-2-yl]ethanoic acid, B-cell lymphoma 6 protein, CHLORIDE ION 著者 Robb, G, Ferguson, A, Hargreaves, D. 登録日 2017-02-06 公開日 2017-05-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017

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