PDB: 37932 件ウェブページステータス検索Chemie searchBIRD

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7MH0	Human CTPS1 bound to CTP 分子名称: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Lynch, E.M, Kollman, J.M. 登録日 2021-04-14 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIU	Mouse CTPS2 bound to inhibitor R80 分子名称: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
6YBQ	Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... 著者 Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. 登録日 2020-03-17 公開日 2020-10-28 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (1.96 Å) 主引用文献 A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
6XZQ	Influenza C virus polymerase in complex with human ANP32A - Subclass 1 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2020-02-05 公開日 2020-11-25 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6Y3O	14-3-3 Sigma in complex with phosphorylated CAMKK2 peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CAMKK2, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-18 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
7M7E	6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 分子名称: 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
7M7F	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
7M7G	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
7M7H	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
7M7I	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
7MEY	Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron 分子名称: 2-(ethylamino)ethane-1-thiol, E3 ubiquitin-protein ligase UBR1, Monoubiquitinated N-degron, ... 著者 Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M. 登録日 2021-04-08 公開日 2021-11-24 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature, 600, 2021
7MEX	Structure of yeast Ubr1 in complex with Ubc2 and N-degron 分子名称: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ... 著者 Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M. 登録日 2021-04-08 公開日 2021-11-24 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature, 600, 2021
6XR3	X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A 分子名称: 3C-like proteinase, N-[(2S)-1-({(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide 著者 Anson, B, Ghosh, A.K, Mesecar, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-07-10 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A To Be Published
6XRR	Structure of SciW bound to the Rhs1 Transmembrane Domain from Salmonella typhimurium 分子名称: Putative cytoplasmic protein, RHS repeat protein, SULFATE ION 著者 Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. 登録日 2020-07-13 公開日 2020-12-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones. Elife, 9, 2020
5W4U	Pol II elongation complex with an N6-methyladenine-containing template 分子名称: 14mer non-template DNA, 29mer template DNA, 9mer RNA, ... 著者 Wang, W, Wang, D. 登録日 2017-06-13 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
2ZE6	Crystal Structure of adenosine phosphate-isopentenyltransferase complexed with substrate analog, DMASPP 分子名称: ADENOSINE MONOPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Isopentenyl transferase 著者 Sakakibara, H. 登録日 2007-12-06 公開日 2008-02-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insight into the reaction mechanism and evolution of cytokinin biosynthesis. Proc.Natl.Acad.Sci.Usa, 105, 2008
6XRB	Crystal structure of SciW from Salmonella typhimurium 分子名称: SciW, TRIETHYLENE GLYCOL 著者 Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. 登録日 2020-07-11 公開日 2020-12-30 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones. Elife, 9, 2020
5W6Q	Structural basis for recognition of artificial DNA by an evolved KlenTaq variant 分子名称: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ... 著者 Singh, I, Georgiadis, M.M. 登録日 2017-06-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Nucleic Acids Res., 46, 2018
5VNF	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif 分子名称: C-terminal VV Sorting motif: VAL-THR-SER-VAL-VAL, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5W51	Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP 分子名称: 14mer non-template DNA, 29mer template DNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... 著者 Wang, W, Wang, D. 登録日 2017-06-13 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.404 Å) 主引用文献 Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
6X62	Legionella pneumophila Dot T4SS OMC 分子名称: DotC, DotD, Inner membrane lipoprotein YiaD, ... 著者 Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. 登録日 2020-05-27 公開日 2020-09-30 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
5W6Z	Crystal structure of the H24W mutant of HsNUDT16 分子名称: SODIUM ION, U8 snoRNA-decapping enzyme 著者 Thirawatananond, P, Gabelli, S.B. 登録日 2017-06-18 公開日 2018-12-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Sci Rep, 9, 2019
6X65	Legionella pneumophila Dot/Icm T4SS 分子名称: DotC, DotD, Inner membrane lipoprotein YiaD, ... 著者 Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. 登録日 2020-05-27 公開日 2020-10-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
6XAA	SARS CoV-2 PLpro in complex with ubiquitin propargylamide 分子名称: Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
6XB2	Room temperature X-ray crystallography reveals catalytic cysteine in the SARS-CoV-2 3CL Mpro is highly reactive: Insights for enzyme mechanism and drug design 分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Kneller, D.W, Kovalevsky, A, Coates, L. 登録日 2020-06-05 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design. Iucrj, 7, 2020

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