7N9I
 
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7N69
 
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7MYJ
 
 | Structure of full length human AMPK (a2b1g1) in complex with a small molecule activator MSG011 | 分子名称: | (5S,6R,7R,9R,13cR,14R,16aS)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5H,13cH-5,9-epoxy-4b,9a,1 5-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-ol, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, ... | 著者 | Ovens, A.J, Gee, Y.S, Ling, N.X.Y, Waters, N.J, Yu, D, Scott, J.W, Parker, M.W, Hoffman, N.J, Kemp, B.E, Baell, J.B, Oakhill, J.S, Langendorf, C.G. | 登録日 | 2021-05-21 | 公開日 | 2022-06-29 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator. Biochem.J., 479, 2022
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7N9U
 
 | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions | 分子名称: | Capsid protein, Nanobody | 著者 | Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions To Be Published
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3D4K
 
 | Concanavalin A Complexed to a Synthetic Analog of the Trimannoside | 分子名称: | CALCIUM ION, Concanavalin-A, GLYCEROL, ... | 著者 | Kadirvelraj, R, Foley, B.L, Dyekjaer, J.D, Woods, R.J. | 登録日 | 2008-05-14 | 公開日 | 2009-03-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Involvement of water in carbohydrate-protein binding: concanavalin A revisited. J.Am.Chem.Soc., 130, 2008
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7N9X
 
 | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions | 分子名称: | Capsid protein, Nanobody, Peptidyl-prolyl cis-trans isomerase A | 著者 | Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.511 Å) | 主引用文献 | CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions To Be Published
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3CUJ
 
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7MU5
 
 | Human DCTPP1 bound to Triptolide | 分子名称: | MAGNESIUM ION, dCTP pyrophosphatase 1, triptolide | 著者 | Hauk, G, Berger, J.M. | 登録日 | 2021-05-14 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance To Be Published
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7MY6
 
 | Se-CrtE C-term His-tag with IPP added | 分子名称: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Peat, T.S, Newman, J. | 登録日 | 2021-05-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
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7MME
 
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7MMD
 
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7MZO
 
 | Crystal structure of the UcaD lectin-binding domain | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | 登録日 | 2021-05-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. Plos Pathog., 18, 2022
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7N8W
 
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7MZP
 
 | Crystal structure of the UclD lectin-binding domain | 分子名称: | F17-like fimbril adhesin subunit UclD, IODIDE ION | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | 登録日 | 2021-05-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. Plos Pathog., 18, 2022
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7N8V
 
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7N3Y
 
 | Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain E59Q/D222N Mutant in Complex with DNA | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ... | 著者 | Wojtaszek, J.L, Krahn, J, Wallace, B.D, Williams, R.S. | 登録日 | 2021-06-02 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2. Cell Rep, 41, 2022
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7N3Z
 
 | Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA-(apurinic or apyrimidinic site) endonuclease 2, ... | 著者 | Wojtaszek, J.L, Wallace, B.D, Williams, R.S. | 登録日 | 2021-06-02 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2. Cell Rep, 41, 2022
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7N4K
 
 | 6218 TCR in complex with H2-Db PA 224 | 分子名称: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | 著者 | Szeto, C, Gras, S. | 登録日 | 2021-06-04 | 公開日 | 2022-07-20 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
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7N5C
 
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7N5P
 
 | 6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant | 分子名称: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | 著者 | Szeto, C, Gras, S. | 登録日 | 2021-06-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
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7N99
 
 | SDE2 SAP domain apo structure | 分子名称: | Isoform 2 of Replication stress response regulator SDE2 | 著者 | Paung, Y, Weinheimer, A.S, Rageul, J, Khan, A, Ho, B, Tong, M, Alphonse, S, Seeliger, M.A, Kim, H. | 登録日 | 2021-06-17 | 公開日 | 2022-10-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks. J.Biol.Chem., 298, 2022
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7NAQ
 
 | Human PA200-20S proteasome complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2021-06-22 | 公開日 | 2022-11-02 | 最終更新日 | 2025-05-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAP
 
 | Human PA28-20S-PA28 proteasome complex | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2021-06-22 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAO
 
 | Human PA28-20S proteasome complex | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | 登録日 | 2021-06-22 | 公開日 | 2022-11-02 | 最終更新日 | 2025-05-28 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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7MKT
 
 | Crystal structure of r(GU)11G-NMM complex | 分子名称: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | 著者 | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | 登録日 | 2021-04-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
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