7N5C
6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond
Summary for 7N5C
Entry DOI | 10.2210/pdb7n5c/pdb |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, peptide from Polymerase acidic protein, ... (7 entities in total) |
Functional Keywords | major histocompatibility complex, mhc, mouse, influenza a, polymerase acidic protein, h2db, t cell receptor, pa224-233, disulfide bond, cysteine, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 5 |
Total formula weight | 95324.26 |
Authors | |
Primary citation | Szeto, C.,Zareie, P.,Wirasinha, R.C.,Zhang, J.B.,Nguyen, A.T.,Riboldi-Tunnicliffe, A.,La Gruta, N.L.,Gras, S.,Daley, S.R. Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13:4951-4951, 2022 Cited by PubMed: 35999236DOI: 10.1038/s41467-022-32692-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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