7N5C

6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond

Summary for 7N5C

• Entry DOI: 10.2210/pdb7n5c/pdb
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, peptide from Polymerase acidic protein, ... (7 entities in total)
• Functional Keywords: major histocompatibility complex, mhc, mouse, influenza a, polymerase acidic protein, h2db, t cell receptor, pa224-233, disulfide bond, cysteine, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 5
• Total formula weight: 95324.26

Authors

Szeto, C.,Gras, S. (deposition date: 2021-06-05, release date: 2022-07-20, Last modification date: 2023-10-18)

• Primary citation: Szeto, C.,Zareie, P.,Wirasinha, R.C.,Zhang, J.B.,Nguyen, A.T.,Riboldi-Tunnicliffe, A.,La Gruta, N.L.,Gras, S.,Daley, S.R.; Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.; Nat Commun, 13:4951-4951, 2022; PubMed: 35999236; DOI: 10.1038/s41467-022-32692-4

Experimental method

X-RAY DIFFRACTION (1.87 Å)