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8E2R
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BU of 8e2r by Molmil
Crystal structure of TadAC-1.14
分子名称: GLYCEROL, ZINC ION, tRNA-specific adenosine deaminase 1.14
著者Feliciano, P.R, Lee, S.J, Ciaramella, G.
登録日2022-08-15
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Improved cytosine base editors generated from TadA variants.
Nat.Biotechnol., 41, 2023
9EOE
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BU of 9eoe by Molmil
TF type tau filament from V337M mutant
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Qi, C, Scheres, S.H.W, Michel, G.
登録日2024-03-14
公開日2024-07-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.
Biorxiv, 2024
9J1T
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BU of 9j1t by Molmil
Structure of a triple-helix region of human Collagen type IV from Trautec
分子名称: GLYCEROL, Triple-helix region of human collagen type IV
著者Fan, X, Chu, Y, Zhai, Y, Fu, S, Li, D, Feng, P, Cao, K, Wu, X, Cai, H, Wang, H, Qian, S.
登録日2024-08-05
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of a triple-helix region of human Collagen type IV from Trautec
To Be Published
9CER
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BU of 9cer by Molmil
Guillardia theta Fanzor (GtFz) State 1
分子名称: Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1, RNA (142-MER), ZINC ION
著者Xu, P, Saito, M, Zhang, F.
登録日2024-06-27
公開日2024-09-11
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
9ESM
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BU of 9esm by Molmil
Archaellum filament from the Halobacterium salinarum deltaAgl26 strain
分子名称: Archaellin, beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose
著者Grosmann-Haham, I, Shahar, A.
登録日2024-03-26
公開日2024-07-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility.
Nat Commun, 15, 2024
9C3C
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BU of 9c3c by Molmil
Cryo-EM structure of native dystrophin-glycoprotein complex (DGC)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-dystroglycan, ...
著者Liu, S, Su, T, Xia, X, Zhou, Z.H.
登録日2024-05-31
公開日2024-10-23
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Native DGC Structure Rationalizes Muscular Dystrophy-Causing Mutations
To Be Published
9FAA
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BU of 9faa by Molmil
Cryo-EM structure of cardiac collagen-associated amyloid AL59
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC)
著者Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S.
登録日2024-05-10
公開日2024-07-17
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
9IJD
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BU of 9ijd by Molmil
Carazolol-activated human beta3 adrenergic receptor
分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, Beta-3 adrenergic receptor, Camelid antibody VHH fragment, ...
著者Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X.
登録日2024-06-22
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker.
Chempluschem, 2024
9CF2
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BU of 9cf2 by Molmil
Parasitella parasitica Fanzor (PpFz) State 3
分子名称: DNA non-target strand, DNA substrate model, DNA target strand, ...
著者Xu, P, Saito, M, Zhang, F.
登録日2024-06-27
公開日2024-09-11
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
9FGT
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BU of 9fgt by Molmil
SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76 (focused refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain fragment scFv76, Spike glycoprotein,Fibritin
著者Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M.
登録日2024-05-25
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of scFv76 in complex with SARS-CoV-2 Omicron Spike protein
To Be Published
8Y0R
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BU of 8y0r by Molmil
Complex of FMDV A/WH/CHA/09 and inter-serotype broadly neutralizing antibodies pOA-2
分子名称: VP1 of capsid protein, VP2 of capsid protein, VP3 of capsid protein, ...
著者Wu, S, Lei, D.
登録日2024-01-23
公開日2024-10-09
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Discovery, evolution and recognizing antigenic structures of cross-serotype broadly neutralizing antibodies from porcine B-cell repertoires against foot-and-mouth disease virus
To Be Published
9BK5
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BU of 9bk5 by Molmil
Structure of LNG binder complex
分子名称: Alpha-cobratoxin, LNG binder
著者Bera, A.K, Torres, S.V, Kang, A, Baker, D.
登録日2024-04-26
公開日2024-10-09
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献De novo designed proteins neutralize lethal snake venom toxins
To Be Published
9IK2
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BU of 9ik2 by Molmil
The co-crystal structure of SARS-CoV-2 Mpro in complex with compound H109
分子名称: 3C-like proteinase, tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S)-1-azanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-1-oxidanylidene-3-phenyl-propan-2-yl]amino]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate
著者Feng, Y, Zheng, W.Y, Han, P, Fu, L.F, Qi, J.X.
登録日2024-06-26
公開日2024-07-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent in vitro and in vivo antiviral activities
To Be Published
9FMM
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BU of 9fmm by Molmil
Structure of human ACE2 in complex with a fluorinated small molecule inhibitor
分子名称: (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Benoit, R.B, Rodrigues, M.J, Wieser, M.M.
登録日2024-06-06
公開日2024-07-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2.
Eur J Nucl Med Mol Imaging, 2024
9CJA
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BU of 9cja by Molmil
Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure
分子名称: ZINC ION, Zinc finger protein 711
著者Rua, A.J, Alexandrescu, A.T.
登録日2024-07-05
公開日2024-07-17
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure.
Protein Sci., 33, 2024
9EVM
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BU of 9evm by Molmil
High pH (8.0) nitrite-bound MSOX movie series dataset 30 of the copper nitrite reductase (NirK) from Bradyrhizobium japonicum USDA110 [20.7 MGy]
分子名称: COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION, ...
著者Rose, S.L, Ferroni, F.M, Horrell, S, Brondino, C.D, Eady, R.R, Jaho, S, Hough, M.A, Owen, A.L, Antonyuk, S.V, Hasnain, S.S.
登録日2024-03-30
公開日2024-07-24
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Spectroscopically Validated pH-dependent MSOX Movies Provide Detailed Mechanism of Copper Nitrite Reductases.
J.Mol.Biol., 436, 2024
9F14
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BU of 9f14 by Molmil
The crystal structure of full length tetramer CysB from Klebsiella aerogenes in complex with N-acetylserine
分子名称: HTH-type transcriptional regulator CysB, N-ACETYL-SERINE
著者Verschueren, K.H.G, Dodson, E.J, Wilkinson, A.J.
登録日2024-04-18
公開日2024-07-24
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structure of the LysR-type Transcriptional Regulator, CysB, Bound to the Inducer, N-acetylserine.
Eur.Biophys.J., 53, 2024
6EPK
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BU of 6epk by Molmil
CRYSTAL STRUCTURE OF THE PRECURSOR MEMBRANE PROTEIN-ENVELOPE PROTEIN HETERODIMER FROM THE YELLOW FEVER VIRUS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, GLYCEROL, ...
著者Rey, F.A, Duquerroy, S, Crampon, E, Barba-Spaeth, G.
登録日2017-10-11
公開日2018-10-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex
Mbio, 2023
9B1D
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BU of 9b1d by Molmil
Cryo-EM structure of native SWR1 bound to DNA (composite structure)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, DNA (147-MER), ...
著者Louder, R.K, Park, G, Wu, C.
登録日2024-03-13
公開日2024-10-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler.
Cell, 2024
9CUZ
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BU of 9cuz by Molmil
Bufavirus 1 complexed with 6SLN
分子名称: N-acetyl-alpha-neuraminic acid, VP1
著者Gulkis, M.C, McKenna, R, Bennett, A.D.
登録日2024-07-27
公開日2024-09-18
実験手法ELECTRON MICROSCOPY (2.16 Å)
主引用文献Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
9FFF
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BU of 9fff by Molmil
dsDNA-FANCD2-FANCI complex
分子名称: DNA (32-MER), DNA (33-MER), Fanconi anemia complementation group I, ...
著者Alcon, P, Passmore, L.A.
登録日2024-05-23
公開日2024-07-31
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.
Nature, 632, 2024
9BK7
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BU of 9bk7 by Molmil
Structure of SHRT_binder
分子名称: SHRT_binder
著者Bera, A.K, Torres, S.V, Kang, A, Baker, D.
登録日2024-04-26
公開日2024-10-09
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献De novo designed proteins neutralize lethal snake venom toxinsides
To Be Published
8G3Y
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BU of 8g3y by Molmil
MBP-Mcl1 in complex with ligand 34
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Miller, B.R, Shaffer, P.
登録日2023-02-08
公開日2023-05-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein-Protein Interaction Modulator with the Potential of Treating Hematological Malignancies.
J.Med.Chem., 66, 2023
9BMK
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BU of 9bmk by Molmil
GH5_4 endo-beta(1,3/1,4)-glucanase E331A from Segatella copri in complex with cellotriose
分子名称: Cellulase (Glycosyl hydrolase family 5), SULFATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Cordeiro, R.L, Golisch, B, Brumer, H, Van Petegem, F.
登録日2024-05-02
公開日2024-10-09
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献The molecular basis of cereal mixed-linkage beta-glucan utilization by the human gut bacterium Segatella copri.
J.Biol.Chem., 300, 2024
9EM0
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BU of 9em0 by Molmil
OPR3 wild type in its dimeric form with special L6 conformation
分子名称: 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE, PENTAETHYLENE GLYCOL
著者Bijelic, A, Macheroux, P, Kerschbaumer, B.
登録日2024-03-07
公開日2024-08-14
最終更新日2024-08-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer.
Sci Rep, 14, 2024

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件を2024-10-30に公開中

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