PDB: 185749 件ウェブページステータス検索Chemie searchBIRD

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1XCD	Dimeric bovine tissue-extracted decorin, crystal form 1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin 著者 Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J. 登録日 2004-09-01 公開日 2004-11-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan Proc.Natl.Acad.Sci.Usa, 101, 2004
5OQT	Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, ALANINE, ... 著者 Jungnickel, K.E.J, Newstead, S. 登録日 2017-08-14 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nat Commun, 9, 2018
3FFW	Crystal Structure of CheY triple mutant F14Q, N59K, E89Y complexed with BeF3- and Mn2+ 分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY, GLYCEROL, ... 著者 Pazy, Y, Collins, E.J, Bourret, R.B. 登録日 2008-12-04 公開日 2009-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Matching Biochemical Reaction Kinetics to the Timescales of Life: Structural Determinants That Influence the Autodephosphorylation Rate of Response Regulator Proteins. J.Mol.Biol., 392, 2009
1E2J	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
1DYU	The active site base controls cofactor reactivity in Escherichia coli amine oxidase: X-ray crystallographic studies with mutational variants. 分子名称: CALCIUM ION, COPPER (II) ION, COPPER AMINE OXIDASE 著者 Murray, J.M, Wilmot, C.M, Saysell, C.G, Jaeger, J, Knowles, P.F, Phillips, S.E.V, McPherson, M.J. 登録日 2000-02-08 公開日 2000-02-29 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 The Active Site Base Controls Cofactor Reactivity in Escherichia Coli Amine Oxidase : X-Ray Crystallographicstudies with Mutational Variants Biochemistry, 38, 1999
1E2H	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
2X7O	Crystal structure of TGFbRI complexed with an indolinone inhibitor 分子名称: (3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]AMINO}METHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-6-CARBOXAMIDE, TGF-BETA RECEPTOR TYPE I 著者 Roth, G.J, Heckel, A, Brandl, T, Grauert, M, Hoerer, S, Kley, J.T, Schnapp, G, Baum, P, Mennerich, D, Schnapp, A, Park, J.E. 登録日 2010-03-03 公開日 2010-10-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri) J.Med.Chem., 53, 2010
1E2N	HPT + HMTT 分子名称: 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2001-03-31 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
1E2P	Thymidine kinase, DHBT 分子名称: 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, SULFATE ION, THYMIDINE KINASE 著者 Schulz, G.E, Kessler, U. 登録日 2000-05-23 公開日 2001-04-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
5L40	polyketide ketoreductase SimC7 - apo crystal form 1 分子名称: polyketide ketoreductase SimC7 著者 Schafer, M, Stevenson, C.E.M, Wilkinson, B, Lawson, D.M, Buttner, M.J. 登録日 2016-05-24 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate. Cell Chem Biol, 23, 2016
6MEI	Crystal structure of broadly neutralizing antibody HEPC3 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2018-09-06 公開日 2018-11-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe, 24, 2018
2C7H	Solution NMR structure of the DWNN domain from human RBBP6 分子名称: RETINOBLASTOMA-BINDING PROTEIN 6, ISOFORM 3 著者 Pugh, D.J.R, Ab, E, Faro, A, Lutya, P.T, Hoffmann, E, Rees, D.J.G. 登録日 2005-11-24 公開日 2006-01-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Dwnn, a Novel Ubiquitin-Like Domain, Implicates Rbbp6 in Mrna Processing and Ubiquitin-Like Pathways Bmc Struct.Biol., 6, 2006
5OXN	PepTSt in complex with dipeptide Phe-Ala 分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... 著者 Martinez Molledo, M, Quistgaard, E.M, Loew, C. 登録日 2017-09-07 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.196 Å) 主引用文献 Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
1X7D	Crystal Structure Analysis of Ornithine Cyclodeaminase Complexed with NAD and ornithine to 1.6 Angstroms 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-ornithine, ... 著者 Alam, S, Goodman, J.L, Wang, S, Ruzicka, F.J, Frey, P.A, Wedekind, J.E. 登録日 2004-08-13 公開日 2004-11-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for the u-Crystallin Family Biochemistry, 43, 2004
1X8M	X-ray structure of pectin degrading enzyme 5-keto 4-deoxyuronate isomerase from Escherichia coli 分子名称: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 著者 Fedorov, A.A, Fedorov, E.V, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2004-08-18 公開日 2004-09-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The crystal structure of pectin degrading enzyme 5-keto 4-deoxyuronate isomerase from Escherichia coli To be Published
3T07	Crystal structure of S. aureus Pyruvate Kinase in complex with a naturally occurring bis-indole alkaloid 分子名称: (3S,5R)-3,5-bis(6-bromo-1H-indol-3-yl)piperazin-2-one, PHOSPHATE ION, Pyruvate kinase 著者 Worrall, L.J, Vuckovic, M, Strynadka, N.C.J. 登録日 2011-07-19 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities. J.Biol.Chem., 286, 2011
5OY3	The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ... 著者 Jones, S.E, Olsen, L, Gajhede, M. 登録日 2017-09-07 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.136 Å) 主引用文献 Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57, 2018
5OYE	GH5 endo-xyloglucanase from Cellvibrio japonicus 分子名称: CHLORIDE ION, Cellulase, putative, ... 著者 Attia, M, Nelson, C.E, Offen, W.A, Jain, N, Gardner, J.G, Davies, G.J, Brumer, H. 登録日 2017-09-08 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 In vitro and in vivo characterization of threeCellvibrio japonicusglycoside hydrolase family 5 members reveals potent xyloglucan backbone-cleaving functions. Biotechnol Biofuels, 11, 2018
1HVJ	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-3-HYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
4A6W	X-ray structures of oxazole hydroxamate EcMetAp-Mn complexes 分子名称: 5-(2-chlorophenyl)-N-hydroxy-1,3-oxazole-2-carboxamide, MANGANESE (II) ION, METHIONINE AMINOPEPTIDASE 著者 Huguet, F, Melet, A, AlvesdeSousa, R, Lieutaud, A, Chevalier, J, Deschamps, P, Tomas, A, Leulliot, N, Pages, J.M, Artaud, I. 登録日 2011-11-09 公開日 2012-06-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes. Chemmedchem, 7, 2012
1XBZ	Crystal structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound L-xylulose 5-phosphate 分子名称: 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, L-XYLULOSE 5-PHOSPHATE, MAGNESIUM ION 著者 Wise, E.L, Yew, W.S, Akana, J, Gerlt, J.A, Rayment, I. 登録日 2004-08-31 公開日 2005-04-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase Biochemistry, 44, 2005
1HVI	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
1DKY	THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 2 NATIVE CRYSTALS 分子名称: DNAK, PEPTIDE SUBSTRATE 著者 Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. 登録日 1996-06-03 公開日 1996-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 272, 1996
1XBY	Structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/T169A mutant with bound D-ribulose 5-phosphate 分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, MAGNESIUM ION, RIBULOSE-5-PHOSPHATE 著者 Wise, E.L, Yew, W.S, Akana, J, Gerlt, J.A, Rayment, I. 登録日 2004-08-31 公開日 2005-04-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase Biochemistry, 44, 2005
1HVK	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994

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