PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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1L26	REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY 分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME 著者 Bell, J.A, Dao-Pin, S, Matthews, B.W. 登録日 1989-05-01 公開日 1990-01-15 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability. Science, 239, 1988
1DQ9	COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA 分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, PROTEIN (HMG-COA REDUCTASE) 著者 Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J. 登録日 1999-12-30 公開日 2000-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis. EMBO J., 19, 2000
1DRU	ESCHERICHIA COLI DHPR/NADH COMPLEX 分子名称: DIHYDRODIPICOLINATE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Reddy, S.G, Scapin, G, Blanchard, J.S. 登録日 1996-06-28 公開日 1997-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes. Biochemistry, 35, 1996
6I53	Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ... 著者 Laverty, D, Desai, R, Uchanski, T, Masiulis, S, Wojciech, J.S, Malinauskas, T, Zivanov, J, Pardon, E, Steyaert, J, Miller, K.W, Aricescu, A.R. 登録日 2018-11-12 公開日 2019-01-02 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the human alpha 1 beta 3 gamma 2 GABAAreceptor in a lipid bilayer. Nature, 565, 2019
1L44	CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991
4DVY	Crystal structure of the Helicobacter pylori CagA oncoprotein 分子名称: Cytotoxicity-associated immunodominant antigen 著者 Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M. 登録日 2012-02-23 公開日 2012-07-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA Cell Host Microbe, 12, 2012
1L58	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 To be Published
1LJ3	CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6 分子名称: Lysozyme C, NITRATE ION 著者 Saraswathi, N.T, Sankaranarayanan, R, Vijayan, M. 登録日 2002-04-19 公開日 2002-10-19 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effect of stabilizing additives on the structure and hydration of proteins: a study involving monoclinic lysozyme. Acta Crystallogr.,Sect.D, 58, 2002
1LJK	CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 15% TREHALOSE 分子名称: Lysozyme C, NITRATE ION 著者 Saraswathi, N.T, Sankaranarayanan, R, Vijayan, M. 登録日 2002-04-21 公開日 2002-10-19 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Effect of stabilizing additives on the structure and hydration of proteins: a study involving monoclinic lysozyme. Acta Crystallogr.,Sect.D, 58, 2002
1L64	TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Heinz, D, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc.Natl.Acad.Sci.USA, 89, 1992
1DYE	DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Zhang, X, Matthews, B.W. 登録日 1993-05-13 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme. J.Mol.Biol., 235, 1994
1LL7	STRUCTURE OF THE E171Q MUTANT OF C. IMMITIS CHITINASE 1 分子名称: CHITINASE 1 著者 Bortone, K, Monzingo, A.F, Ernst, S, Robertus, J.D. 登録日 2002-04-26 公開日 2002-12-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 THE STRUCTURE OF AN ALLOSAMIDIN COMPLEX WITH THE COCCIDIOIDES IMMITIS CHITINASE DEFINES A ROLE FOR A SECOND ACID RESIDUE IN SUBSTRATE-ASSISTED MECHANISM J.Mol.Biol., 320, 2002
3GHU	Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Forth stage of radiation damage. 分子名称: Aldose reductase, CITRIC ACID, IDD594, ... 著者 Petrova, T, Ginell, S, Hazemann, I, Mitschler, A, Podjarny, A, Joachimiak, A. 登録日 2009-03-04 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 X-ray-radiation-induced cooperative atomic movements in protein. J.Mol.Biol., 387, 2009
1L71	MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Zhang, X, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992
4TM1	Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADred-NADP+-Br 分子名称: BROMIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, KtzI, ... 著者 Setser, J.W, Drennan, C.L. 登録日 2014-05-30 公開日 2014-09-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase. Biochemistry, 53, 2014
1PRN	REFINED STRUCTURE OF PORIN FROM RHODOPSEUDOMONAS BLASTICA AND COMPARISON WITH THE PORIN FROM RHODOBACTER CAPSULATUS 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, PORIN 著者 Kreusch, A, Schulz, G.E. 登録日 1994-07-13 公開日 1994-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Refined structure of the porin from Rhodopseudomonas blastica. Comparison with the porin from Rhodobacter capsulatus. J.Mol.Biol., 243, 1994
4RQ5	Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG)and dATP soaked with MgCl2 for 60 s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ACETATE ION, CHLORIDE ION, ... 著者 Vyas, R, Suo, Z. 登録日 2014-10-31 公開日 2015-04-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137, 2015
3HHN	Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD 分子名称: Class I ligase ribozyme, self-ligation product, MAGNESIUM ION, ... 著者 Shechner, D.M, Grant, R.A, Bagby, S.C, Bartel, D.P. 登録日 2009-05-15 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
1L76	TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Sauer, U, Matthews, B.W. 登録日 1991-09-23 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions. J.Biol.Chem., 267, 1992
1DWH	Study on radiation damage on a cryocooled crystal. Part 4: Structure after irradiation with 27.2*10e15 photons/mm2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Burmeister, W.P. 登録日 1999-12-05 公開日 2000-03-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Changes in a Cryo-Cooled Protein Crystal due to Radiation Damage Acta Crystallogr.,Sect.D, 56, 2000
1LQ2	Crystal structure of barley beta-D-glucan glucohydrolase isoenzyme Exo1 in complex with gluco-phenylimidazole 分子名称: (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-PHENYL-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Hrmova, M, De Gori, R, Smith, B.J, Vasella, A, Varghese, J.N, Fincher, G.B. 登録日 2002-05-09 公開日 2003-11-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Three-dimensional Structure of the Barley {beta}-D-Glucan Glucohydrolase in Complex with a Transition State Mimic. J.Biol.Chem., 279, 2004
6FZE	BBE31 from Lyme disease agent Borrelia (Borreliella) burgdorferi playing a vital role in successful colonization of the mammalian host (native data) 分子名称: GLUTATHIONE, Putative surface protein, SULFATE ION 著者 Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K. 登録日 2018-03-14 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione. Biochim Biophys Acta Gen Subj, 1864, 2019
2Z4V	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GGPP (inhibitory site) 分子名称: GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
2Z78	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-806 分子名称: 3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2,2-diphosphonoethyl)pyridinium, Geranylgeranyl pyrophosphate synthetase 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-08-16 公開日 2008-07-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
1L91	SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Eriksson, A.E, Matthews, B.W. 登録日 1992-01-21 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J.Mol.Biol., 229, 1993

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