3GHU
Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Forth stage of radiation damage.
Summary for 3GHU
Entry DOI | 10.2210/pdb3ghu/pdb |
Related | 1US0 2I16 2I17 2pev 2pf8 2pfh 3GHR 3GHS 3GHT |
Descriptor | Aldose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ... (5 entities in total) |
Functional Keywords | oxidoreductase, acetylation, cataract, cytoplasm, nadp, phosphoprotein, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15121 |
Total number of polymer chains | 1 |
Total formula weight | 37252.12 |
Authors | Petrova, T.,Ginell, S.,Hazemann, I.,Mitschler, A.,Podjarny, A.,Joachimiak, A. (deposition date: 2009-03-04, release date: 2009-03-24, Last modification date: 2023-09-06) |
Primary citation | Petrova, T.,Lunin, V.Y.,Ginell, S.,Hazemann, I.,Lazarski, K.,Mitschler, A.,Podjarny, A.,Joachimiak, A. X-ray-radiation-induced cooperative atomic movements in protein. J.Mol.Biol., 387:1092-1105, 2009 Cited by PubMed: 19233199DOI: 10.1016/j.jmb.2009.02.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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