3GHU
Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Forth stage of radiation damage.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aldose reductase | polymer | 316 | 35898.3 | 1 | UniProt (P15121) Pfam (PF00248) In PDB | Homo sapiens (human) | AR, Aldehyde reductase |
2 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
3 | A | IDD594 | non-polymer | 416.2 | 1 | Chemie (LDT) | |||
4 | A | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
5 | water | water | 18.0 | 630 | Chemie (HOH) |
Sequence modifications
A: 0 - 315 (UniProt: P15121)
PDB | External Database | Details |
---|---|---|
Ile 4 | Leu 5 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35898.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1353.8 | |
All* | Total formula weight | 37252.1 |