PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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5HLP	X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 分子名称: 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. 登録日 2016-01-15 公開日 2016-05-25 最終更新日 2016-07-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
5HLX	X-ray crystal structure of met F43H/H64A sperm whale myoglobin in complex with nitrite 分子名称: Myoglobin, NITRITE ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Yuan, H. 登録日 2016-01-15 公開日 2016-05-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Regulating the nitrite reductase activity of myoglobin by redesigning the heme active center Nitric Oxide, 57, 2016
7QR4	human CPEB3 HDV-like ribozyme 分子名称: RNA CPEB3 ribozyme, U1 small nuclear ribonucleoprotein A 著者 Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O. 登録日 2022-01-17 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes Biorxiv, 2022
8DB2	Q108K:K40L:T51C:T53A:R58L:Q38F mutant of hCRBPII bound to synthetic fluorophore CM1V 分子名称: (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form, Retinol-binding protein 2 著者 Bingham, C.R, Geiger, J.H, Borhan, B, Staples, R. 登録日 2022-06-14 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Light controlled reversible Michael addition of cysteine: a new tool for dynamic site-specific labeling of proteins. Analyst, 148, 2023
7QHW	TTBK1 kinase domain in complex with inhibitor 29 分子名称: GLYCEROL, SULFATE ION, Tau-tubulin kinase 1, ... 著者 Nozal, V, Liehta, D. 登録日 2021-12-14 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
5HMV	Re refinement of 4mwk. 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... 著者 Helliwell, J.R. 登録日 2016-01-17 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)]. Struct Dyn, 3, 2016
5KPK	Glycogen Synthase Kinase 3 beta Complexed with BRD0209 分子名称: (4~{S})-3-cyclopropyl-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
7QDD	NMR structure of Npl3 RRM1 bound to the AUCCAA RNA 分子名称: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3') 著者 Clery, A, Allain, F.H.-T, Moursy, A. 登録日 2021-11-26 公開日 2022-10-26 最終更新日 2024-01-10 実験手法 SOLUTION NMR 主引用文献 RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. Nat Commun, 14, 2023
5HNC	Synchrotron X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels 分子名称: Lysozyme C 著者 Tsukui, S, Kimura, F, Kusaka, K, Baba, S, Mizuno, N, Kimura, T. 登録日 2016-01-18 公開日 2016-07-20 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Neutron and X-ray single-crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels. Acta Crystallogr D Struct Biol, 72, 2016
5KQY	Protease E35D-DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease E35D-DRV 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
5HNL	In-house X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels 分子名称: Lysozyme C 著者 Tsukui, S, Kimura, F, Kusaka, K, Baba, S, Mizuno, N, Kimura, T. 登録日 2016-01-18 公開日 2016-07-20 実験手法 X-RAY DIFFRACTION (2.424 Å) 主引用文献 Neutron and X-ray single-crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels. Acta Crystallogr D Struct Biol, 72, 2016
8RZV	Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA 分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-02-13 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA To Be Published
8D1C	Crystal structure of T252E-CYP199A4 in complex with 4-(Trifluoromethoxy)benzoic acid 分子名称: 4-(trifluoromethoxy)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2022-05-27 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light. Chemistry, 28, 2022
8QZE	Heme-domain BM3 variant 21B3_F87V-A328F 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, IMIDAZOLE, ... 著者 Opperman, D.J, Ebrecht, A.C, Aschenbrenner, J.C. 登録日 2023-10-27 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Mol Catal, 557, 2024
8R7G	Crystal structure of the kinase domain of ACVR1 (ALK2) with M4K2234 分子名称: 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide, Activin receptor type I 著者 Williams, E.P, Cros, J, Ensan, D, Smil, D, Edwards, A.M, O'Meara, J.A, Fernandez-Cid, A, Isaac, M.B, Al-awar, R, Bullock, A.N. 登録日 2023-11-24 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
5KTH	Structure of cow mincle complexed with brartemicin 分子名称: 2,4-dihydroxy-6-methyl Benzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ... 著者 Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I. 登録日 2016-07-11 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle. J.Biol.Chem., 291, 2016
7QR3	Chimpanzee CPEB3 HDV-like ribozyme 分子名称: GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ... 著者 Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes Biorxiv, 2022
5L2Q	Serine/threonine-protein kinase 40 (STK40) kinase homology domain 分子名称: Serine/threonine-protein kinase 40 著者 Durzynska, I, Uljon, S, Blacklow, S.C. 登録日 2016-08-02 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1. Structure, 25, 2017
8D6L	Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V 分子名称: (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form, GLYCEROL, ... 著者 Bingham, C.R, Geiger, J.H, Borhan, B. 登録日 2022-06-06 公開日 2023-02-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Light controlled reversible Michael addition of cysteine: a new tool for dynamic site-specific labeling of proteins. Analyst, 148, 2023
5L3H	Re-refinement of 4dd4; cisplatin coordination chemistry determination at hen egg white lysozyme His15 with standard uncertainties 分子名称: AMMONIA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Helliwell, J.R, Tanley, S.W.M. 登録日 2016-05-06 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cisplatin coordination chemistry determination at hen egg white lysozyme His15 with ligand distances and angles, and their standard uncertainties, and also reporting a split occupancy effect ArXiv, 2016
5KU8	Crystal structure of CK2 分子名称: 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... 著者 Ferguson, A.D, Dowling, J. 登録日 2016-07-13 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystal structure of CK2 Not Published
7Q7C	Room temperature structure of the human Serine/Threonine Kinase 17B (STK17B/DRAK2) in complex with ADP at atmospheric pressure 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase 17B 著者 Lieske, J, Guenther, S, Saouane, S, Meents, A. 登録日 2021-11-09 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Room temperature structure of the human Serine/Threonine Kinase 17B (STK17B/DRAK2) in complex with ADP at atmospheric pressure To Be Published
7Q7A	Room temperature structure of RNase A at 120 MPa helium gas pressure in a sapphire capillary 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... 著者 Lieske, J, Guenther, S, Saouane, S, Meents, A. 登録日 2021-11-09 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Fixed-target high-pressure macromolecular crystallography To Be Published
5KVY	CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG 分子名称: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60 著者 Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T. 登録日 2016-07-15 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60. Plos One, 15, 2020
5HTD	Recombinant bovine beta-lactoglobulin variant L1A/I2S with endogenous ligand (sBlgB#1) 分子名称: Beta-lactoglobulin, MYRISTIC ACID 著者 Loch, J.I, Bonarek, P, Tworzydlo, M, Polit, A, Hawro, B, Lach, A, Ludwin, E, Lewinski, K. 登録日 2016-01-26 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineered beta-Lactoglobulin Produced in E. coli: Purification, Biophysical and Structural Characterisation. Mol Biotechnol., 58, 2016

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