PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

---

1AVG	THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS 分子名称: THROMBIN, TRIABIN 著者 Fuentes-Prior, P, Huber, R, Bode, W. 登録日 1997-09-16 公開日 1998-12-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug. Proc.Natl.Acad.Sci.USA, 94, 1997
3N29	Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni 分子名称: Carboxynorspermidine decarboxylase, GLYCEROL, N-(3-aminopropyl)propane-1,3-diamine, ... 著者 Deng, X, Lee, J, Michael, A.J, Tomchick, D.R, Goldsmith, E.J, Phillips, M.A. 登録日 2010-05-17 公開日 2010-06-09 最終更新日 2012-02-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. J.Biol.Chem., 285, 2010
4KCG	Human dCK C4S-S74E mutant in complex with UDP and the DI-39 inhibitor 分子名称: Deoxycytidine kinase, N-{2-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide, URIDINE-5'-DIPHOSPHATE 著者 Nomme, J, Lavie, A. 登録日 2013-04-24 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. J.Exp.Med., 211, 2014
4H8S	Crystal structure of human APPL2BARPH domain 分子名称: DCC-interacting protein 13-beta 著者 Martin, J.L, King, G.J. 登録日 2012-09-23 公開日 2012-10-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase. J.Biol.Chem., 287, 2012
4K0X	X-ray Crystal Structure of OXA-23 from Acinetobacter baumannii 分子名称: BICARBONATE ION, Beta-lactamase 著者 Klinger, N.V, Ramey, M.E, Leonard, D.A, Powers, R.A. 登録日 2013-04-04 公開日 2013-08-07 最終更新日 2013-10-23 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam. Antimicrob.Agents Chemother., 57, 2013
4K0W	X-ray crystal structure of OXA-23 A220 duplication clinical variant 分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, Beta-lactamase, ... 著者 Kaitany, K.J, Klinger, N.V, Leonard, D.A, Powers, R.A. 登録日 2013-04-04 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam. Antimicrob.Agents Chemother., 57, 2013
4IXD	X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution 分子名称: 4-(3-{4-[(3-aminopropyl)carbamoyl]phenyl}-1H-indazol-1-yl)-N-methylbenzamide, Integrin alpha-L, MAGNESIUM ION 著者 Kallen, J. 登録日 2013-01-25 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification and x-ray structure based investigation of an ICAM-1 binding enhancing small molecule activator of LFA-1 To be Published, 2013
4IVN	The Vibrio vulnificus NanR protein complexed with ManNAc-6P 分子名称: 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose, Transcriptional regulator 著者 Hwang, J, Kim, M.H. 登録日 2013-01-23 公開日 2013-07-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the regulation of sialic acid catabolism by the Vibrio vulnificus transcriptional repressor NanR Proc.Natl.Acad.Sci.USA, 110, 2013
4MB9	Structure of Streptococcus pneumonia ParE in complex with AZ13102335 分子名称: 1-ethyl-3-{6-(pyrimidin-5-yl)-5-[(3R)-tetrahydrofuran-3-ylmethoxy][1,3]thiazolo[5,4-b]pyridin-2-yl}urea, DNA topoisomerase IV, B subunit, ... 著者 Ogg, D, Tucker, J. 登録日 2013-08-19 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
4MBC	Structure of Streptococcus pneumonia ParE in complex with AZ13053807 分子名称: 1-{5-[2-(morpholin-4-yl)ethoxy]-6-(pyridin-3-yl)[1,3]thiazolo[5,4-b]pyridin-2-yl}-3-prop-2-en-1-ylurea, DNA topoisomerase IV, B subunit 著者 Ogg, D, Tucker, J. 登録日 2013-08-19 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
4LZS	Crystal Structure of BRD4(1) bound to inhibitor XD46 分子名称: 4-acetyl-3-ethyl-N,5-dimethyl-1H-pyrrole-2-carboxamide, Bromodomain-containing protein 4 著者 Wohlwend, D, Huegle, M, Einsle, O, Gerhardt, S. 登録日 2013-08-01 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
4MKH	Crystal structure of a stable adenylate kinase variant AKv18 分子名称: 1,2-ETHANEDIOL, Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ... 著者 Moon, S, Bae, E. 登録日 2013-09-05 公開日 2014-03-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An integrated approach for thermal stabilization of a mesophilic adenylate kinase. Proteins, 82, 2014
4L5B	Human dCK C4S-S74E mutant in complex with UDP and the DI-43 inhibitor 分子名称: 1-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]-2-methylpropan-2-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE 著者 Nomme, J, Lavie, A. 登録日 2013-06-10 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. J.Med.Chem., 56, 2013
4NQI	Structure of the N-terminal I-BAR domain (1-259) of D.Discoideum IBARa 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, SH3 domain-containing protein 著者 Witte, G, Faix, J, Runge-Wollmann, P. 登録日 2013-11-25 公開日 2014-02-05 最終更新日 2014-04-02 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 The inverse BAR domain protein IBARa drives membrane remodeling to control osmoregulation, phagocytosis and cytokinesis. J.Cell.Sci., 127, 2014
3P2O	Crystal Structure of FolD Bifunctional Protein from Campylobacter jejuni 分子名称: Bifunctional protein folD, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Kim, Y, Zhang, R, Makowska-Grzyska, M, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-10-03 公開日 2010-10-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.227 Å) 主引用文献 Crystal Structure of FolD Bifunctional Protein from To be Published
4LYS	Crystal Structure of BRD4(1) bound to Colchiceine 分子名称: Bromodomain-containing protein 4, N-[(7S)-10-hydroxy-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, SODIUM ION 著者 Wohlwend, D, Gerhardt, S, Einsle, O. 登録日 2013-07-31 公開日 2014-01-15 最終更新日 2014-01-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
4O9W	Crystal structure of polo-like kinase(PLK1)PBD in complex with phospho peptide 分子名称: Serine/threonine-protein kinase PLK1, phospho peptide VAL-LEU-SER-TPO-LEU-NH2 著者 Bong, S.M, Lee, B.I, Kim, K.T. 登録日 2014-01-03 公開日 2014-08-13 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores. Nat Commun, 5, 2014
4MTX	Structure of the ERS1 dimerization and histidine phosphotransfer domain from Arabidopsis thaliana 分子名称: Ethylene response sensor 1 著者 Mayerhofer, H, Mueller-Dieckmann, J. 登録日 2013-09-20 公開日 2014-10-01 最終更新日 2015-03-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Model of the Cytosolic Domain of the Plant Ethylene Receptor 1 (ETR1). J.Biol.Chem., 290, 2015
4MOT	Structure of Streptococcus pneumonia pare in complex with AZ13072886 分子名称: 1-[4-(3-methylbutyl)-5-oxo-6-(pyridin-3-yl)-4,5-dihydro[1,3]thiazolo[5,4-b]pyridin-2-yl]-3-prop-2-en-1-ylurea, Topoisomerase IV subunit B 著者 Ogg, D, Boriack-Sjodin, P.A. 登録日 2013-09-12 公開日 2013-11-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thiazolopyridone ureas as DNA gyrase B inhibitors: Optimization of antitubercular activity and efficacy. Bioorg.Med.Chem.Lett., 24, 2014
7ICD	REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE 分子名称: ISOCITRATE DEHYDROGENASE 著者 Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M. 登録日 1990-05-30 公開日 1991-10-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Regulation of an enzyme by phosphorylation at the active site. Science, 249, 1990
7HBI	SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72V, CO-LIGANDED FORM 分子名称: CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE 著者 Royer Junior, W.E. 登録日 1998-06-25 公開日 1998-11-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity. J.Mol.Biol., 284, 1998
4MT8	Structure of the ERS1 dimerization and histidine phosphotransfer domain from Arabidopsis thaliana 分子名称: Ethylene response sensor 1 著者 Mayerhofer, H, Mueller-Dieckmann, J. 登録日 2013-09-19 公開日 2014-10-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Model of the Cytosolic Domain of the Plant Ethylene Receptor 1 (ETR1). J.Biol.Chem., 290, 2015
2N6A	NMR structure of a human calmodulin/connexin-36 peptide hybrid 分子名称: CALCIUM ION, human calmodulin/connexin-36 peptide hybrid 著者 Donaldson, L. 登録日 2015-08-14 公開日 2015-08-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An investigation of calcium mediate signaling by the Connexin 36 gap junction protein To be Published
3GOJ	Barium bound to the Holliday sequence d(CCGGCGCCGG)4 分子名称: 5'-D(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3', BARIUM ION 著者 Naseer, A, Cardin, C.J. 登録日 2009-03-19 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Barium bound to the Holliday junction structure To be Published
2GWC	Crystal structure of plant glutamate cysteine ligase in complex with a transition state analogue 分子名称: (2S)-2-amino-4-(S-butylsulfonimidoyl)butanoic acid, Glutamate cysteine ligase, MAGNESIUM ION 著者 Hothorn, M, Wachter, A, Gromes, R, Stuwe, T, Rausch, T, Scheffzek, K. 登録日 2006-05-04 公開日 2006-06-20 最終更新日 2018-10-03 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structural basis for the redox control of plant glutamate cysteine ligase. J.Biol.Chem., 281, 2006

<949596979899100101102103104105106107108109>