4IXD

X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution

Summary for 4IXD

• Entry DOI: 10.2210/pdb4ixd/pdb
• Related: 1XDG
• Descriptor: Integrin alpha-L, MAGNESIUM ION, 4-(3-{4-[(3-aminopropyl)carbamoyl]phenyl}-1H-indazol-1-yl)-N-methylbenzamide, ... (4 entities in total)
• Functional Keywords: rossman-fold, i-domain, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P20701
• Total number of polymer chains: 1
• Total formula weight: 21877.36

Authors

Kallen, J. (deposition date: 2013-01-25, release date: 2014-01-29, Last modification date: 2023-09-20)

• Primary citation: Hintersteiner, M.,Kallen, J.,Schmied, M.,Jung, T.,Graf, C.,Mudd, G.,Gstach, H.,Auer, M.; Identification and x-ray structure based investigation of an ICAM-1 binding enhancing small molecule activator of LFA-1; To be Published, 2013

Experimental method

X-RAY DIFFRACTION (1.8 Å)