4IXD
X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-L | polymer | 188 | 21425.6 | 1 | UniProt (P20701) Pfam (PF00092) | Homo sapiens (human) | CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | 4-(3-{4-[(3-aminopropyl)carbamoyl]phenyl}-1H-indazol-1-yl)-N-methylbenzamide | non-polymer | 427.5 | 1 | Chemie (1HV) | |||
| 4 | D (A) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A: 127 - 311 (UniProt: P20701)
| PDB | External Database | Details |
|---|---|---|
| Met 124 | - | expression tag |
| Ala 125 | - | expression tag |
| Ser 126 | - | expression tag |
| Trp 189 | Arg 214 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21425.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 451.8 | |
| All* | Total formula weight | 21877.4 |
