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7NAX
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BU of 7nax by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement)
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
登録日2021-01-25
公開日2021-12-08
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAR
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BU of 7nar by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement)
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
登録日2021-01-25
公開日2021-12-08
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
3B6C
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BU of 3b6c by Molmil
Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with (S)-DNPA
分子名称: ActII protein, [(3S)-9-hydroxy-1-methyl-10-oxo-4,10-dihydro-3H-benzo[g]isochromen-3-yl]acetic acid
著者Willems, A.R, Junop, M.S.
登録日2007-10-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA.
J.Mol.Biol., 376, 2008
8K2D
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BU of 8k2d by Molmil
Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A
分子名称: 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ...
著者Buschauer, R, Beckmann, R, Cheng, J.
登録日2023-07-12
公開日2024-07-10
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
3AFR
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BU of 3afr by Molmil
Crystal Structure of VDR-LBD/22S-Butyl-1a,24R-dihydroxyvitamin D3 complex
分子名称: (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2-butyl-4-hydroxy-1,5-dimethylhexyl]-7a-methyloctahydro-4H-inden-4-yli dene}ethylidene]-4-methylidenecyclohexane-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
著者Inaba, Y, Nakabayashi, M, Itoh, T, Ikura, T, Ito, N, Yamamoto, K.
登録日2010-03-10
公開日2010-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献22S-Butyl-1alpha,24R-dihydroxyvitamin D(3): Recovery of vitamin D receptor agonistic activity
J.Steroid Biochem.Mol.Biol., 121, 2010
3RZW
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BU of 3rzw by Molmil
Crystal Structure of the Monobody ySMB-9 bound to human SUMO1
分子名称: GLYCEROL, Monobody ySMB-9, Small ubiquitin-related modifier 1
著者Gilbreth, R.N, Koide, S.
登録日2011-05-12
公開日2011-12-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.
J.Mol.Biol., 415, 2012
2ZXN
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BU of 2zxn by Molmil
A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the Ligand-binding Pocket
分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2-hydroxyethyl)heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
著者Nakabayashi, M, Ikura, T, Ito, N.
登録日2009-01-04
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor
J.Med.Chem., 52, 2009
6HRW
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BU of 6hrw by Molmil
EthR2 in complex with compound 1 (BDM14272)
分子名称: (1~{S},5~{R})-8-[2-(4-chlorophenyl)ethyl]-8-azabicyclo[3.2.1]octan-3-one, Probable transcriptional regulatory protein
著者Wintjens, R, Wohlkonig, A, Tanina, A.
登録日2018-09-28
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem, 167, 2019
6HS2
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BU of 6hs2 by Molmil
EthR2 in complex with compound 31 (BDM76150)
分子名称: (1~{S},5~{R})-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-8-azabicyclo[3.2.1]octan-3-one, Probable transcriptional regulatory protein
著者Wintjens, R, Wohlkonig, A, Tanina, A.
登録日2018-09-28
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem, 167, 2019
6BH8
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BU of 6bh8 by Molmil
Crystal structure of ZMPSTE24 in complex with phosphoramidon
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CAAX prenyl protease 1 homolog, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ...
著者Goblirsch, B.R, Arachea, B.T, Wiener, M.C.
登録日2017-10-30
公開日2018-08-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.
Acta Crystallogr D Struct Biol, 74, 2018
4YZ6
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BU of 4yz6 by Molmil
Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]
分子名称: Protein TIFY 10A, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y.
登録日2015-03-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
3ADV
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BU of 3adv by Molmil
Human PPARgamma ligand-binding domain in complex with serotonin
分子名称: Peroxisome proliferator-activated receptor gamma, SEROTONIN
著者Waku, T, Shiraki, T, Oyama, T, Morikawa, K.
登録日2010-01-29
公開日2010-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The nuclear receptor PPARgamma individually responds to serotonin- and fatty acid-metabolites
Embo J., 29, 2010
4N4F
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BU of 4n4f by Molmil
Crystal Structure of the Bromodomain-PHD Finger Module of Human Transcriptional Co-Activator CBP in complex with di-Acetylated Histone 4 Peptide (H412acK16ac).
分子名称: CREB-binding protein, Histone 4 Peptide, ZINC ION
著者Plotnikov, A.N, Zhou, J, Zhou, M.-M.
登録日2013-10-08
公開日2014-02-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP.
Structure, 22, 2014
3I0R
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BU of 3i0r by Molmil
crystal structure of HIV reverse transcriptase in complex with inhibitor 3
分子名称: Reverse transcriptase/ribonuclease H, S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate, p51 RT
著者Yan, Y, Prasad, S.
登録日2009-06-25
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
Bioorg.Med.Chem.Lett., 19, 2009
3U5V
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BU of 3u5v by Molmil
Crystal structure of Max-E47
分子名称: NITRATE ION, Protein max, Transcription factor E2-alpha chimera
著者Guarne, A, Ahmadpour, F, Gloyd, M.
登録日2011-10-11
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the minimalist max-e47 protein chimera.
Plos One, 7, 2012
3KYC
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BU of 3kyc by Molmil
Human SUMO E1 complex with a SUMO1-AMP mimic
分子名称: 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
7OE0
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BU of 7oe0 by Molmil
E. coli pre-30S delta rbfA ribosomal subunit class F
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E.
登録日2021-04-30
公開日2021-07-14
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
7OE1
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BU of 7oe1 by Molmil
30S ribosomal subunit from E. coli
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E.
登録日2021-04-30
公開日2021-07-14
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center.
Int J Mol Sci, 22, 2021
2YO3
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BU of 2yo3 by Molmil
Salmonella enterica SadA 1185-1386 fused to GCN4 adaptors (SadAK14)
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4, PUTATIVE INNER MEMBRANE PROTEIN
著者Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N.
登録日2012-10-20
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Complete Fiber Structures of Complex Trimeric Autotransporter Adhesins Conserved in Enterobacteria.
Proc.Natl.Acad.Sci.USA, 109, 2012
2VBY
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BU of 2vby by Molmil
Feast or famine regulatory protein (Rv3291c)from M. tuberculosis complexed with L-Tyrosine
分子名称: TRANSCRIPTIONAL REGULATORY PROTEIN, TYROSINE
著者Shrivastava, T, Ramachandran, R.
登録日2007-09-18
公開日2007-11-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic Insights from the Crystal Structures of a Feast/Famine Regulatory Protein from Mycobacterium Tuberculosis H37Rv.
Nucleic Acids Res., 35, 2007
3C2B
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BU of 3c2b by Molmil
Crystal structure of TetR transcriptional regulator from Agrobacterium tumefaciens
分子名称: FORMIC ACID, Transcriptional regulator, TetR family
著者Osipiuk, J, Skarina, T, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-01-24
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of TetR transcriptional regulator from Agrobacterium tumefaciens.
To be Published
2VC1
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BU of 2vc1 by Molmil
Feast or famine regulatory protein (Rv3291c)from M. tuberculosis complexed with L-Methionine
分子名称: METHIONINE, TRANSCRIPTIONAL REGULATORY PROTEIN
著者Shrivastava, T, Ramachandran, R.
登録日2007-09-18
公開日2007-11-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mechanistic Insights from the Crystal Structures of a Feast/Famine Regulatory Protein from Mycobacterium Tuberculosis H37Rv.
Nucleic Acids Res., 35, 2007
2ZK0
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BU of 2zk0 by Molmil
Human peroxisome proliferator-activated receptor gamma ligand binding domain
分子名称: Peroxisome proliferator-activated receptor gamma
著者Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K.
登録日2008-03-12
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids
J.Mol.Biol., 385, 2009
3KYD
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BU of 3kyd by Molmil
Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic
分子名称: 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
1WNE
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BU of 1wne by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA
分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2004-07-31
公開日2004-08-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem., 279, 2004

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