7NAX
| Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
|
|
7NAR
| Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
|
|
3B6C
| |
8K2D
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
3AFR
| Crystal Structure of VDR-LBD/22S-Butyl-1a,24R-dihydroxyvitamin D3 complex | 分子名称: | (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2-butyl-4-hydroxy-1,5-dimethylhexyl]-7a-methyloctahydro-4H-inden-4-yli dene}ethylidene]-4-methylidenecyclohexane-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | 著者 | Inaba, Y, Nakabayashi, M, Itoh, T, Ikura, T, Ito, N, Yamamoto, K. | 登録日 | 2010-03-10 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 22S-Butyl-1alpha,24R-dihydroxyvitamin D(3): Recovery of vitamin D receptor agonistic activity J.Steroid Biochem.Mol.Biol., 121, 2010
|
|
3RZW
| |
2ZXN
| A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the Ligand-binding Pocket | 分子名称: | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2-hydroxyethyl)heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | 著者 | Nakabayashi, M, Ikura, T, Ito, N. | 登録日 | 2009-01-04 | 公開日 | 2009-02-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor J.Med.Chem., 52, 2009
|
|
6HRW
| EthR2 in complex with compound 1 (BDM14272) | 分子名称: | (1~{S},5~{R})-8-[2-(4-chlorophenyl)ethyl]-8-azabicyclo[3.2.1]octan-3-one, Probable transcriptional regulatory protein | 著者 | Wintjens, R, Wohlkonig, A, Tanina, A. | 登録日 | 2018-09-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2. Eur J Med Chem, 167, 2019
|
|
6HS2
| EthR2 in complex with compound 31 (BDM76150) | 分子名称: | (1~{S},5~{R})-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-8-azabicyclo[3.2.1]octan-3-one, Probable transcriptional regulatory protein | 著者 | Wintjens, R, Wohlkonig, A, Tanina, A. | 登録日 | 2018-09-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2. Eur J Med Chem, 167, 2019
|
|
6BH8
| Crystal structure of ZMPSTE24 in complex with phosphoramidon | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CAAX prenyl protease 1 homolog, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... | 著者 | Goblirsch, B.R, Arachea, B.T, Wiener, M.C. | 登録日 | 2017-10-30 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | 主引用文献 | Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24. Acta Crystallogr D Struct Biol, 74, 2018
|
|
4YZ6
| Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221] | 分子名称: | Protein TIFY 10A, Transcription factor MYC3 | 著者 | Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y. | 登録日 | 2015-03-24 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling. Nature, 525, 2015
|
|
3ADV
| Human PPARgamma ligand-binding domain in complex with serotonin | 分子名称: | Peroxisome proliferator-activated receptor gamma, SEROTONIN | 著者 | Waku, T, Shiraki, T, Oyama, T, Morikawa, K. | 登録日 | 2010-01-29 | 公開日 | 2010-12-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | The nuclear receptor PPARgamma individually responds to serotonin- and fatty acid-metabolites Embo J., 29, 2010
|
|
4N4F
| |
3I0R
| crystal structure of HIV reverse transcriptase in complex with inhibitor 3 | 分子名称: | Reverse transcriptase/ribonuclease H, S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate, p51 RT | 著者 | Yan, Y, Prasad, S. | 登録日 | 2009-06-25 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Bioorg.Med.Chem.Lett., 19, 2009
|
|
3U5V
| |
3KYC
| Human SUMO E1 complex with a SUMO1-AMP mimic | 分子名称: | 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... | 著者 | Lima, C.D. | 登録日 | 2009-12-05 | 公開日 | 2010-02-16 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
|
|
7OE0
| E. coli pre-30S delta rbfA ribosomal subunit class F | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E. | 登録日 | 2021-04-30 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center. Int J Mol Sci, 22, 2021
|
|
7OE1
| 30S ribosomal subunit from E. coli | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E. | 登録日 | 2021-04-30 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center. Int J Mol Sci, 22, 2021
|
|
2YO3
| |
2VBY
| |
3C2B
| Crystal structure of TetR transcriptional regulator from Agrobacterium tumefaciens | 分子名称: | FORMIC ACID, Transcriptional regulator, TetR family | 著者 | Osipiuk, J, Skarina, T, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-01-24 | 公開日 | 2008-02-05 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystal structure of TetR transcriptional regulator from Agrobacterium tumefaciens. To be Published
|
|
2VC1
| |
2ZK0
| Human peroxisome proliferator-activated receptor gamma ligand binding domain | 分子名称: | Peroxisome proliferator-activated receptor gamma | 著者 | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | 登録日 | 2008-03-12 | 公開日 | 2009-02-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
|
|
3KYD
| Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic | 分子名称: | 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ... | 著者 | Lima, C.D. | 登録日 | 2009-12-05 | 公開日 | 2010-02-16 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
|
|
1WNE
| Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA | 分子名称: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | 著者 | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | 登録日 | 2004-07-31 | 公開日 | 2004-08-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
|
|