6BH8
Crystal structure of ZMPSTE24 in complex with phosphoramidon
Summary for 6BH8
| Entry DOI | 10.2210/pdb6bh8/pdb |
| Related | 2YPT 4AW6 5SYT |
| Related PRD ID | PRD_000638 |
| Descriptor | CAAX prenyl protease 1 homolog, ZINC ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... (4 entities in total) |
| Functional Keywords | integral membrane protein, zinc metalloprotease, inhibitor complex, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 113259.84 |
| Authors | Goblirsch, B.R.,Arachea, B.T.,Wiener, M.C. (deposition date: 2017-10-30, release date: 2018-08-15, Last modification date: 2023-10-04) |
| Primary citation | Goblirsch, B.R.,Arachea, B.T.,Councell, D.J.,Wiener, M.C. Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24. Acta Crystallogr D Struct Biol, 74:739-747, 2018 Cited by PubMed: 30082509DOI: 10.1107/S2059798318003431 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.85 Å) |
Structure validation
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