1OY9
| Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | 分子名称: | Acriflavine resistance protein B, ETHIDIUM | 著者 | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | 登録日 | 2003-04-03 | 公開日 | 2003-05-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OYD
| Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | 分子名称: | Acriflavine resistance protein B, DEQUALINIUM | 著者 | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | 登録日 | 2003-04-03 | 公開日 | 2003-05-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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6BZS
| Human ABCC6 NBD1 in Apo state | 分子名称: | Multidrug resistance-associated protein 6, SULFATE ION | 著者 | Zheng, A, Thibodeau, P.H. | 登録日 | 2017-12-26 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.29990458 Å) | 主引用文献 | Structural analysis reveals pathomechanisms associated with pseudoxanthoma elasticum-causing mutations in the ABCC6 transporter. J. Biol. Chem., 293, 2018
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4ZLL
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4ZLJ
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4ZLN
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5AZO
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5NIK
| Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump | 分子名称: | Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC | 著者 | Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D. | 登録日 | 2017-03-24 | 公開日 | 2017-05-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nat Microbiol, 2, 2017
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5NIL
| Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump-MacB section | 分子名称: | Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC | 著者 | Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D. | 登録日 | 2017-03-24 | 公開日 | 2017-05-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nat Microbiol, 2, 2017
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7M33
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8F4B
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1IWG
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7OUK
| BDM88855 inhibitor bound to the transmembrane domain of AcrB | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl didecanoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, ... | 著者 | Tam, H.K, Foong, W.E, Pos, K.M. | 登録日 | 2021-06-12 | 公開日 | 2021-12-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun, 13, 2022
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7OUL
| BDM88832 inhibitor bound to the transmembrane domain of AcrB-R971A | 分子名称: | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 1-(3-chloranyl-5-iodanyl-pyridin-2-yl)piperazine, ... | 著者 | Tam, H.K, Foong, W.E, Pos, K.M. | 登録日 | 2021-06-12 | 公開日 | 2021-12-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun, 13, 2022
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7OUM
| BDM88855 inhibitor bound to the transmembrane domain of AcrB-R971A | 分子名称: | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 3-chloranyl-2-piperazin-1-yl-quinoline, ... | 著者 | Tam, H.K, Foong, W.E, Pos, K.M. | 登録日 | 2021-06-12 | 公開日 | 2021-12-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun, 13, 2022
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5NC5
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8SX9
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8SXA
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6CSX
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5XJJ
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6BAJ
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6SGR
| Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin | 分子名称: | DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB | 著者 | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | 登録日 | 2019-08-05 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28, 2020
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5YCK
| Crystal structure of a MATE family protein derived from Camelina sativa at 2.3 angstrom | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, RUBIDIUM ION, multi drug efflux transporter | 著者 | Tanaka, Y, Tsukazaki, T, Iwaki, S. | 登録日 | 2017-09-07 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of a Plant Multidrug and Toxic Compound Extrusion Family Protein Structure, 25, 2017
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6SGS
| Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc | 分子名称: | DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB | 著者 | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | 登録日 | 2019-08-05 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28, 2020
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5LQ3
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