PDB: 494 件ウェブページステータス検索Chemie searchBIRD

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7JK7	Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant 分子名称: GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
5HUY	Structure of HCMV Small Terminase NLS bound to importin alpha 分子名称: HCMV small terminase, Importin subunit alpha-1 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2016-01-28 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits. J.Biol.Chem., 291, 2016
5HUW	Structure of HSV-1 Large Terminase NLS bound to importin alpha 分子名称: HSV1 large terminase NLS, Importin subunit alpha-1 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2016-01-27 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits. J.Biol.Chem., 291, 2016
3EA5	Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... 著者 Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. 登録日 2008-08-24 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008
4WV6	Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8 分子名称: 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8 著者 Trowitzsch, S. 登録日 2014-11-04 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
7CRU	hnRNPK NLS in complex with Importin alpha 1 (KPNA2) 分子名称: ACETATE ION, GLYCEROL, Heterogeneous nuclear ribonucleoprotein K, ... 著者 Yao, J, Sun, Q. 登録日 2020-08-14 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN. Cell.Mol.Life Sci., 78, 2021
8ECH	Tick-borne encephalitis virus capsid protein NLS bound to host importin alpha 2 分子名称: Capsid protein C, Importin subunit alpha-1 著者 Roby, J.A, Forwood, J.K. 登録日 2022-09-02 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure and biological functions of tick-borne encephalitis virus capsid protein To Be Published
8F0X	Cryo-EM structure of Kap114 bound to H2A-H2B 分子名称: Histone H2A.2, Histone H2B.2, Importin subunit beta-5 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8F19	Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) 分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-5, ... 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8F1E	Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) and H2A-H2B 分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Histone H2A.2, ... 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8GHS	Empty HBV Cp183 capsid with importin-beta, subparticle reconstruction at 2-fold location 分子名称: Capsid protein 著者 Kim, C, Schlicksup, C.J, Hadden-Perilla, J.A, Wang, J.C.-Y, Zlotnick, A. 登録日 2023-03-10 公開日 2023-08-09 最終更新日 2023-09-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit. J.Biol.Chem., 299, 2023
3UVU	Structural basis of nuclear import of Flap endonuclease 1 (FEN1) 分子名称: Flap endonuclease 1 (Fen1) peptide, Importin subunit alpha-2 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2011-11-30 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Structural basis of nuclear import of flap endonuclease 1 (FEN1). Acta Crystallogr.,Sect.D, 68, 2012
8G6V	Hepatitis B virus capsid bound to importin alpha1/beta heterodimer 分子名称: Core protein Cp183 著者 Yang, R, Cingolani, G. 登録日 2023-02-16 公開日 2024-01-24 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
8G8Y	Hepatitis B virus capsid bound to importin alpha1 分子名称: Core protein Cp183 著者 Yang, R, Cingolani, G. 登録日 2023-02-20 公開日 2024-01-31 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
1EE4	CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE 分子名称: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN 著者 Conti, E. 登録日 2000-01-30 公開日 2000-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure Fold.Des., 8, 2000
1EE5	YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE 分子名称: KARYOPHERIN ALPHA, NUCLEOPLASMIN 著者 Conti, E. 登録日 2000-01-30 公開日 2000-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure Fold.Des., 8, 2000
6XTE	Human karyopherin RanBP5 (isoform-1) 分子名称: Antipain, CHLORIDE ION, Importin-5, ... 著者 Swale, C, McCarthy, A.A, Ruigrok, R.W.H, Crepin, T. 登録日 2020-01-16 公開日 2020-04-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
6XU2	Human karyopherin RanBP5 (isoform-3) 分子名称: Antipain, Importin-5, NICKEL (II) ION 著者 Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T. 登録日 2020-01-17 公開日 2020-04-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.834 Å) 主引用文献 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
5MRW	Structure of the KdpFABC complex 分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... 著者 Huang, C, Pedersen, B.P, Stokes, D.L. 登録日 2016-12-27 公開日 2017-06-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the potassium-importing KdpFABC membrane complex. Nature, 546, 2017
3RR4	tRNA-Guanine Transglycosylase in complex with N-Methyl-lin-Benzoguanine Inhibitor 分子名称: 2,6-bis(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Klebe, G, Immekus, F, Heine, A. 登録日 2011-04-29 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters. Chemistry, 18, 2012
3SM0	tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor 分子名称: 4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Klebe, G, Immekus, F, Heine, A. 登録日 2011-06-27 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters. Chemistry, 18, 2012
3TLL	tRNA-Guanine Transglycosylase in complex with N-Ethyl-lin-benzoguanine Inhibitor 分子名称: 6-(ethylamino)-2-(methylamino)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Klebe, G, Immekus, F, Heine, A. 登録日 2011-08-30 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters. Chemistry, 18, 2012
3S1G	tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor 分子名称: 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Klebe, G, Immekus, F, Heine, A. 登録日 2011-05-15 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters. Chemistry, 18, 2012
6FVB	Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae 分子名称: Importin beta-like protein KAP120 著者 Vera Rodriguez, A, Huyton, T, Gorlich, D. 登録日 2018-03-01 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (3.297 Å) 主引用文献 Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae To Be Published
4ZJ7	Crystal structure of the karyopherin Kap121p bound to the extreme C-terminus of the protein phosphatase Cdc14p 分子名称: Importin subunit beta-3, Tyrosine-protein phosphatase CDC14 著者 Kobayashi, J, Hirano, H, Matsuura, Y. 登録日 2015-04-29 公開日 2015-06-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the karyopherin Kap121p bound to the extreme C-terminus of the protein phosphatase Cdc14p Biochem.Biophys.Res.Commun., 463, 2015

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