PDB: 1731 件ウェブページステータス検索Chemie searchBIRD

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1JA0	CYPOR-W677X 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. 登録日 2001-05-29 公開日 2001-08-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J.Biol.Chem., 276, 2001
1J9Z	CYPOR-W677G 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. 登録日 2001-05-29 公開日 2001-08-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J.Biol.Chem., 276, 2001
1JA1	CYPOR-Triple Mutant 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. 登録日 2001-05-29 公開日 2001-08-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J.Biol.Chem., 276, 2001
6UDL	Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2700 分子名称: Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, [(1S)-1-(chloromethyl)-1,6-dihydropyrrolo[3,2-e]indol-3(2H)-yl](5-methoxy-1H-indol-2-yl)methanone 著者 Bart, A.G, Scott, E.E. 登録日 2019-09-19 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Cytochrome P450 binding and bioactivation of tumor-targeted duocarmycin agents Drug Metab.Dispos., 2021
1ULW	Crystal structure of P450nor Ser73Gly/Ser75Gly mutant 分子名称: Cytochrome P450 55A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Oshima, R, Fushinobu, S, Su, F, Li, Z, Takaya, N, Shoun, H. 登録日 2003-09-16 公開日 2004-10-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural evidence for direct hydride transfer from NADH to cytochrome P450nor J.Mol.Biol., 342, 2004
7U00	The crystal structure of WT CYP199A4 bound to 4-(2-chloroethyl)benzoic acid 分子名称: 4-(2-chloroethyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-02-17 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.657 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
7TZM	The crystal structure of WT CYP199A4 bound to 4-iodobenzoic acid 分子名称: 4-iodobenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-02-16 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.524 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
7TZY	The crystal structure of WT CYP199A4 bound to 4-(2-bromoethyl)benzoic acid 分子名称: 4-(2-bromoethyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-02-16 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
7TZN	The crystal structure of WT CYP199A4 bound to 4-fluorobenzoic acid 分子名称: 4-fluorobenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-02-16 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.839 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
7TZW	The crystal structure of WT CYP199A4 bound to 4-chlorobenzoic acid 分子名称: 4-CHLORO-BENZOIC ACID, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-02-16 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.462 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
7TZX	The crystal structure of WT CYP199A4 bound to 4-chloromethylbenzoic acid 分子名称: 4-(chloromethyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Scaffidi-Muta, J, Bell, S.G. 登録日 2022-02-16 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.414 Å) 主引用文献 Cytochrome P450-catalyzed oxidation of halogen-containing substrates. J.Inorg.Biochem., 244, 2023
5VWS	Ligand free structure of Cytochrome P450 TbtJ1 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Gober, J.G, Ghodge, S.V, Brustad, E.M, Bowers, A.A. 登録日 2017-05-22 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.411 Å) 主引用文献 P450-Mediated Non-natural Cyclopropanation of Dehydroalanine-Containing Thiopeptides. ACS Chem. Biol., 12, 2017
1XQD	Crystal structure of P450NOR complexed with 3-pyridinealdehyde adenine dinucleotide 分子名称: CYTOCHROME P450 55A1, NICOTINIC ACID ADENINE DINUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Oshima, R, Fushinobu, S, Takaya, N, Su, F, Wakagi, T, Shoun, H. 登録日 2004-10-12 公開日 2004-10-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evidence for direct hydride transfer from NADH to cytochrome P450nor J.Mol.Biol., 342, 2004
1JIN	P450eryF/ketoconazole 分子名称: CIS-1-ACETYL-4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K. 登録日 2001-07-02 公開日 2001-10-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. J.Mol.Biol., 311, 2001
2V0M	Crystal structure of human P450 3A4 in complex with ketoconazole 分子名称: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Sjogren, T, Ekroos, M. 登録日 2007-05-15 公開日 2007-06-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for Ligand Promiscuity in Cytochrome P450 3A4 Proc.Natl.Acad.Sci.USA, 103, 2006
1JIO	P450eryF/6DEB 分子名称: 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K. 登録日 2001-07-02 公開日 2001-10-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. J.Mol.Biol., 311, 2001
1JIP	P450eryF(A245S)/ketoconazole 分子名称: CIS-1-ACETYL-4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K. 登録日 2001-07-02 公開日 2001-10-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. J.Mol.Biol., 311, 2001
3TBG	Human cytochrome P450 2D6 with two thioridazines bound in active site 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, GLYCEROL, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2011-08-05 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
6CP4	P450CAM D251N MUTANT 分子名称: CAMPHOR, CYTOCHROME P450CAM, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 1998-05-28 公開日 1998-09-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect. Biochemistry, 37, 1998
6G5O	The structure of a carbohydrate active P450 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Robb, C.S, Hehemann, J.H. 登録日 2018-03-29 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
1Q5E	Substrate-free Cytochrome P450epoK 分子名称: P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE 著者 Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. 登録日 2003-08-06 公開日 2003-10-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278, 2003
5XA3	Crystal Structure of P450BM3 with Benzyloxycarbonyl-L-prolyl-L-phenylalanine 分子名称: Bifunctional cytochrome P450/NADPH-P450 reductase, DIMETHYL SULFOXIDE, PHENYLALANINE, ... 著者 Shoji, O, Yanagisawa, S, Stanfield, J.K, Suzuki, K, Kasai, C, Cong, Z, Sugimoto, H, Shiro, Y, Watanabe, Y. 登録日 2017-03-10 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Direct Hydroxylation of Benzene to Phenol by Cytochrome P450BM3 Triggered by Amino Acid Derivatives. Angew. Chem. Int. Ed. Engl., 56, 2017
8Q5J	Cytochrome P450 monooxygenase from Streptomyces scabiei (SscaCYP) 分子名称: Cytochrome P450 107B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Opperman, D.J, Ebrecht, A.C. 登録日 2023-08-09 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Natural alternative heme-environments allow efficient peroxygenase activity by cytochrome P450 monooxygenases Catalysis Science And Technology, 13, 2023
6L69	Crystal structure of CYP154C2 from Streptomyces avermitilis 分子名称: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.H, Fushinobu, S. 登録日 2019-10-28 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis. Biochem.Biophys.Res.Commun., 522, 2020
7DI3	Cytochrome P450 (CYP105D18) W.T. 分子名称: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Do, H, Lee, J.H. 登録日 2020-11-18 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Characterization of high-H 2 O 2 -tolerant bacterial cytochrome P450 CYP105D18: insights into papaverine N-oxidation. Iucrj, 8, 2021

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