PDB: 465 件ウェブページステータス検索Chemie searchBIRD

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4WUC	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from 100 mM NaCl condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2014-10-31 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4WUD	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from no salt condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2014-10-31 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4XC0	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with ACP 分子名称: DI(HYDROXYETHYL)ETHER, Heat shock cognate 90 kDa protein, MAGNESIUM ION, ... 著者 Raman, S, Suguna, K. 登録日 2014-12-17 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XCJ	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 90 kDa protein, MAGNESIUM ION 著者 Raman, S, Suguna, K. 登録日 2014-12-18 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XCL	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with AGS 分子名称: Heat shock cognate 90 kDa protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Raman, S, Suguna, K. 登録日 2014-12-18 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XD8	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with ANP 分子名称: Heat shock cognate 90 kDa protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Raman, S, Suguna, K. 登録日 2014-12-19 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XDM	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with Geldanamycin 分子名称: DI(HYDROXYETHYL)ETHER, GELDANAMYCIN, Heat shock cognate 90 kDa protein 著者 Raman, S, Suguna, K. 登録日 2014-12-19 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XE2	N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with peptide 分子名称: Heat shock cognate 90 kDa protein 著者 Raman, S, Suguna, K. 登録日 2014-12-22 公開日 2015-12-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.199 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90. Sci Rep, 5, 2015
4XIV	Kinase and Dimerization (P3P4) of the Thermotoga maritima CheA kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chemotaxis protein CheA, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Greenswag, A.R, Crane, B.R. 登録日 2015-01-07 公開日 2015-11-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational Transitions that Enable Histidine Kinase Autophosphorylation and Receptor Array Integration. J.Mol.Biol., 427, 2015
4XKA	N-terminal domain of Hsp90 from Dictyostelium discoideum in hexagonal form with glycerol 分子名称: GLYCEROL, Heat shock cognate 90 kDa protein, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Raman, S, Suguna, K. 登録日 2015-01-10 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XKK	Crystal structure of N-terminal domain of Hsp90 from Dictyostelium discoideum 分子名称: Heat shock cognate 90 kDa protein 著者 Raman, S, Suguna, K. 登録日 2015-01-12 公開日 2015-01-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Heat shock protein 90 regulates development in Dictyostelium discoideum J. Mol. Biol., 383, 2008
4XKO	N-terminal domain of Hsp90 from Dictyostelium discoideum in hexagonal form with PEG 分子名称: DI(HYDROXYETHYL)ETHER, Heat shock cognate 90 kDa protein, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Raman, S, Suguna, K. 登録日 2015-01-12 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.455 Å) 主引用文献 First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90 Sci Rep, 5, 2015
4XTJ	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from 100 mM KCl plus 100 mM NaCl condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2015-01-23 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4ZKI	The crystal structure of Histidine Kinase YycG with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Histidine kinase 著者 Cai, Y. 登録日 2015-04-30 公開日 2016-05-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.401 Å) 主引用文献 Conformational dynamics of the essential sensor histidine kinase WalK Acta Crystallogr D Struct Biol, 73, 2017
4ZVI	GYRASE B IN COMPLEX WITH 4,5-DIBROMOPYRROLAMIDE-BASED INHIBITOR 分子名称: DNA gyrase subunit B, IODIDE ION, N-(4-{[(4,5-dibromo-1H-pyrrol-2-yl)carbonyl]amino}benzoyl)glycine 著者 Zidar, N, Macut, H, Tomasic, T, Brvar, M, Montalvao, S, Tammela, P, Solmajer, T, Peterlin Masic, L, Ilas, J, Kikelj, D. 登録日 2015-05-18 公開日 2015-07-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation. J.Med.Chem., 58, 2015
5BOC	Crystal structure of topoisomerase ParE inhibitor 分子名称: 3-methyl-4-({3-[3-methyl-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)benzoic acid, DNA topoisomerase 4 subunit B 著者 Tan, Y.W, Chen, G.Y, Hung, A.W, Hill, J. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Application of Fragment-based Drug Discovery against DNA GyraseB To be published
5BOD	Crystal structure of Streptococcus pneumonia ParE inhibitor 分子名称: (2R)-N-[3-(3,5-dimethylphenyl)-1H-pyrazol-5-yl]-1,4-dioxane-2-carboxamide, DNA topoisomerase 4 subunit B 著者 Tan, Y.W, Chen, G, Hung, A.W, Hill, J. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Application of Fragment-based Drug Discovery against DNA GyraseB to be published
5CPH	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment 分子名称: (3E)-3-(pyridin-3-ylmethylidene)-1,3-dihydro-2H-indol-2-one, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B, ... 著者 Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. 登録日 2015-07-21 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
5CTU	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4(1H)-one, CHLORIDE ION, ... 著者 Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. 登録日 2015-07-24 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
5CTW	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(butanoylamino)thiophene-3-carboxamide, CHLORIDE ION, ... 著者 Andersen, O.A, Barker, J, Hadfield, A.T, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. 登録日 2015-07-24 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
5CTX	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-phenyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, DNA gyrase subunit B, ... 著者 Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. 登録日 2015-07-24 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
5CTY	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ... 著者 Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. 登録日 2015-07-24 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
5D6P	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, DNA gyrase subunit B, ... 著者 Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. 登録日 2015-08-12 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
5D6Q	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, DNA gyrase subunit B, ... 著者 Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. 登録日 2015-08-12 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015
5D7C	Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, DNA gyrase subunit B, ... 著者 Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. 登録日 2015-08-13 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. J.Med.Chem., 58, 2015

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