4ZVI

GYRASE B IN COMPLEX WITH 4,5-DIBROMOPYRROLAMIDE-BASED INHIBITOR

Summary for 4ZVI

Entry DOI	10.2210/pdb4zvi/pdb
Descriptor	DNA gyrase subunit B, N-(4-{[(4,5-dibromo-1H-pyrrol-2-yl)carbonyl]amino}benzoyl)glycine, IODIDE ION, ... (4 entities in total)
Functional Keywords	gyrase b, inhibitor, gyrb, proteros biostructures gmbh, isomerase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0AES7
Total number of polymer chains	1
Total formula weight	42388.84
Authors	Zidar, N.,Macut, H.,Tomasic, T.,Brvar, M.,Montalvao, S.,Tammela, P.,Solmajer, T.,Peterlin Masic, L.,Ilas, J.,Kikelj, D. (deposition date: 2015-05-18, release date: 2015-07-15, Last modification date: 2015-08-26)
Primary citation	Zidar, N.,Macut, H.,Tomasic, T.,Brvar, M.,Montalvao, S.,Tammela, P.,Solmajer, T.,Peterlin Masic, L.,Ilas, J.,Kikelj, D. N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation. J.Med.Chem., 58:6179-6194, 2015 Cited by PubMed: 26126187 DOI: 10.1021/acs.jmedchem.5b00775 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation