5VU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vu8 by Molmil](/molmil-images/mine/5vu8) | |
8J86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j86 by Molmil](/molmil-images/mine/8j86) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*TP*)-3'), ... | 著者 | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | 登録日 | 2023-04-30 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
|
|
6ISH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ish by Molmil](/molmil-images/mine/6ish) | Structure of 9N-I DNA polymerase incorporation with 3'-AL in the active site | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*(DAL))-3'), ... | 著者 | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | 登録日 | 2018-11-16 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
|
|
5IUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iud by Molmil](/molmil-images/mine/5iud) | |
8G9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g9l by Molmil](/molmil-images/mine/8g9l) | DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-02-21 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8D96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d96 by Molmil](/molmil-images/mine/8d96) | Human DNA polymerase alpha/primase elongation complex I bound to primer/template | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | 著者 | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | 登録日 | 2022-06-09 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
|
|
8B9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b9d by Molmil](/molmil-images/mine/8b9d) | Human replisome bound by Pol Alpha | 分子名称: | Cell division control protein 45 homolog, Claspin, DNA Molecule, ... | 著者 | Jones, M.L, Yeeles, J.T.P. | 登録日 | 2022-10-05 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
|
|
6ISG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6isg by Molmil](/molmil-images/mine/6isg) | Structure of 9N-I DNA polymerase incorporation with dG in the active site | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*AP*CP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*G)-3'), ... | 著者 | Linwu, S.W, Maestre-Reyna, M, Tsai, M.D, Tu, Y.H, Chang, W.H. | 登録日 | 2018-11-16 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | 主引用文献 | Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing. Commun Biol, 2, 2019
|
|
8D0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d0b by Molmil](/molmil-images/mine/8d0b) | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template | 分子名称: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | 著者 | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | 登録日 | 2022-05-26 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
|
|
8B9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b9b by Molmil](/molmil-images/mine/8b9b) | |
8B9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b9a by Molmil](/molmil-images/mine/8b9a) | |
8HLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hlz by Molmil](/molmil-images/mine/8hlz) | F8-A22-E4 complex of MPXV in hexameric form | 分子名称: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | 著者 | Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. | 登録日 | 2022-12-02 | 公開日 | 2023-05-31 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
|
|
8G9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g9n by Molmil](/molmil-images/mine/8g9n) | Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | 著者 | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-02-21 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
7LUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7luf by Molmil](/molmil-images/mine/7luf) | HSV1 polymerase ternary complex with dsDNA and PNU-183792 | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | 著者 | Hayes, R.P, Klein, D. | 登録日 | 2021-02-22 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
|
|
8TLQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tlq by Molmil](/molmil-images/mine/8tlq) | |
8FOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fok by Molmil](/molmil-images/mine/8fok) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
|
|
8D9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d9d by Molmil](/molmil-images/mine/8d9d) | Human DNA polymerase-alpha/primase elongation complex II bound to primer/template | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | 著者 | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | 登録日 | 2022-06-09 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
|
|
5EXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5exr by Molmil](/molmil-images/mine/5exr) | Crystal structure of human primosome | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | 登録日 | 2015-11-24 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
|
|
8UCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ucw by Molmil](/molmil-images/mine/8ucw) | Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | 著者 | Mullins, E.A, Chazin, W.C, Eichman, B.F. | 登録日 | 2023-09-27 | 公開日 | 2023-10-11 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8FOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8foc by Molmil](/molmil-images/mine/8foc) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
|
|
8FOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fod by Molmil](/molmil-images/mine/8fod) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | 登録日 | 2022-12-30 | 公開日 | 2023-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
|
|
8Q3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8q3r by Molmil](/molmil-images/mine/8q3r) | Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus | 分子名称: | DNA polymerase, DNA polymerase processivity factor component OPG148, Uracil-DNA glycosylase | 著者 | Burmeister, W.P, Ballandras-Colas, A, Boettcher, B, Grimm, C. | 登録日 | 2023-08-04 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus. Plos Pathog., 20, 2024
|
|
8UCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ucv by Molmil](/molmil-images/mine/8ucv) | Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | 著者 | Mullins, E.A, Chazin, W.C, Eichman, B.F. | 登録日 | 2023-09-27 | 公開日 | 2023-10-11 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
6TNZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tnz by Molmil](/molmil-images/mine/6tnz) | Human polymerase delta-FEN1-PCNA toolbelt | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-12-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
|
|
6V8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v8p by Molmil](/molmil-images/mine/6v8p) | Structure of DNA Polymerase Zeta (Apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
|
|