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4BDQ
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Crystal structure of the GluK2 R775A LBD dimer in complex with glutamate
分子名称: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, GLUTAMIC ACID, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDR
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BU of 4bdr by Molmil
Crystal structure of the GluK2 R775A LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDL
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BU of 4bdl by Molmil
Crystal structure of the GluK2 K531A LBD dimer in complex with glutamate
分子名称: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, GLUTAMIC ACID, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDM
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BU of 4bdm by Molmil
Crystal structure of the GluK2 K531A LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDN
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BU of 4bdn by Molmil
Crystal structure of the GluK2 K531A-T779G LBD dimer in complex with glutamate
分子名称: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, GLUTAMIC ACID, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDO
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BU of 4bdo by Molmil
Crystal structure of the GluK2 K531A-T779G LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4IGT
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BU of 4igt by Molmil
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist ZA302 at 1.24A resolution
分子名称: (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid, GLYCEROL, Glutamate receptor 2, ...
著者Larsen, A.P, Venskutonyte, R, Gajhede, M, Kastrup, J.S, Frydenvang, K.
登録日2012-12-18
公開日2013-03-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
J.Med.Chem., 56, 2013
4IGR
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BU of 4igr by Molmil
Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist ZA302
分子名称: (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid, CHLORIDE ION, Glutamate receptor, ...
著者Larsen, A.P, Venskutonyte, R, Gajhede, M, Kastrup, J.S, Frydenvang, K.
登録日2012-12-18
公開日2013-03-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
J.Med.Chem., 56, 2013
4IO5
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BU of 4io5 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with alanine at 1.72 Angstrom resolution
分子名称: ALANINE, AvGluR1 ligand binding domain, CHLORIDE ION
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.721 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO6
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BU of 4io6 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with methionine at 1.6 Angstrom resolution
分子名称: AvGluR1 ligand binding domain, CHLORIDE ION, METHIONINE
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO4
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BU of 4io4 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with serine at 1.94 Angstrom resolution
分子名称: AvGluR1 ligand binding domain, CHLORIDE ION, GLYCEROL, ...
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.941 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO7
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BU of 4io7 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with phenylalanine at 1.9 Angstrom resolution
分子名称: AvGluR1 ligand binding domain, CHLORIDE ION, PHENYLALANINE
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO2
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BU of 4io2 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with glutamate at 1.37 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor 1
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO3
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BU of 4io3 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with aspartate at 1.66 Angstrom resolution
分子名称: ASPARTIC ACID, AvGluR1 ligand binding domain, CHLORIDE ION
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4ISU
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BU of 4isu by Molmil
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.
分子名称: (4aS,5aR,6R,8aS,8bS)-5a-(carboxymethyl)-8-oxo-2,4a,5a,6,7,8,8a,8b-octahydro-1H-pyrrolo[3',4':4,5]furo[3,2-b]pyridine-6-carboxylic acid, CHLORIDE ION, Glutamate receptor 2, ...
著者Juknaite, L, Frydenvang, K, Kastrup, J.S.
登録日2013-01-17
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.
J.Med.Chem., 56, 2013
4IY6
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BU of 4iy6 by Molmil
Crystal structure of the GLUA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and ME-CX516 at 1.72 A resolution
分子名称: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ...
著者Krintel, C, Frydenvang, K, Harpsoe, K, Gajhede, M, Kastrup, J.S.
登録日2013-01-28
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
4IY5
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BU of 4iy5 by Molmil
Crystal structure of the glua2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and CX516 at 2.0 A resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ...
著者Krintel, C, Frydenvang, K, Harpsoe, K, Gajhede, M, Kastrup, J.S.
登録日2013-01-28
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
4JWY
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BU of 4jwy by Molmil
GluN2D ligand-binding core in complex with propyl-NHP5G
分子名称: (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, Glutamate receptor ionotropic, NMDA 2D
著者Hansen, K.B, Tajima, N, Risgaard, R, Perszyk, R.E, Jorgensen, L, Vance, K.M, Ogden, K.K, Clausen, R.P, Furukawa, H, Traynelis, S.F.
登録日2013-03-27
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.
Mol.Pharmacol., 84, 2013
4JWX
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BU of 4jwx by Molmil
GluN2A ligand-binding core in complex with propyl-NHP5G
分子名称: (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, GluN2A
著者Hansen, K.B, Tajima, N, Risgaard, R, Perszyk, R.E, Jorgensen, L, Vance, K.M, Ogden, K.K, Clausen, R.P, Furukawa, H, Traynelis, S.F.
登録日2013-03-27
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.
Mol.Pharmacol., 84, 2013
4KCC
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BU of 4kcc by Molmil
Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State
分子名称: Glutamate receptor ionotropic, NMDA 1, PHOSPHATE ION
著者Berger, A.J, Lau, A.Y, Mayer, M.L.
登録日2013-04-24
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.894 Å)
主引用文献Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics.
Structure, 21, 2013
4KCD
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BU of 4kcd by Molmil
Crystal Structure of the NMDA Receptor GluN3A Ligand Binding Domain Apo State
分子名称: GLYCEROL, Glutamate receptor ionotropic, NMDA 3A
著者Yao, Y, Lau, A.Y, Mayer, M.L.
登録日2013-04-24
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics.
Structure, 21, 2013
4KFQ
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BU of 4kfq by Molmil
Crystal structure of the NMDA receptor GluN1 ligand binding domain in complex with 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one
分子名称: 1-sulfanyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one, GLYCEROL, Glutamate receptor ionotropic, ...
著者Steffensen, T.B, Tabrizi, F.M, Gajhede, M, Kastrup, J.S.
登録日2013-04-27
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site.
J.Biol.Chem., 288, 2013
4L17
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BU of 4l17 by Molmil
GluA2-L483Y-A665C ligand-binding domain in complex with the antagonist DNQX
分子名称: 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION
著者Lau, A.Y, Blachowicz, L, Roux, B.
登録日2013-06-02
公開日2013-08-14
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A conformational intermediate in glutamate receptor activation.
Neuron, 79, 2013
4LZ7
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BU of 4lz7 by Molmil
Crystal structures of GLuR2 ligand-binding-domain in complex with glutamate and positive allosteric modulators
分子名称: GLUTAMIC ACID, Glutamate receptor 2, N-({(5S)-3-[3-fluoro-4-(pyrrolidin-1-yl)phenyl]-4,5-dihydro-1,2-oxazol-5-yl}methyl)acetamide, ...
著者Pandit, J.
登録日2013-07-31
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery and Characterization of a Novel Dihydroisoxazole Class of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators.
J.Med.Chem., 56, 2013
4LZ5
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BU of 4lz5 by Molmil
Crystal structures of GLuR2 ligand-binding-domain in complex with glutamate and positive allosteric modulators
分子名称: GLUTAMIC ACID, Glutamate receptor 2, N-[(2R)-2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide, ...
著者Pandit, J.
登録日2013-07-31
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery and Characterization of a Novel Dihydroisoxazole Class of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators.
J.Med.Chem., 56, 2013

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