7SQ5
 
 | | Designed trefoil knot protein, variant 3 | | 分子名称: | Designed trefoil knot protein, variant 3, SODIUM ION | | 著者 | Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. | | 登録日 | 2021-11-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
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8ETQ
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5J73
 | | De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | | 分子名称: | protein design 2L4HC2_9 | | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | | 登録日 | 2016-04-05 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
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5J2L
 | | De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | | 分子名称: | protein design 2L4HC2_11 | | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | | 登録日 | 2016-03-29 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
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5J10
 | | De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | | 分子名称: | peptide design 2L4HC2_24 | | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | | 登録日 | 2016-03-28 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
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5J0H
 | | De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | | 分子名称: | Design construct 2L6HC3_13 | | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | | 登録日 | 2016-03-28 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
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8GL3
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8FLX
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5JQZ
 | | Designed two-ring homotetramer at 3.8A resolution | | 分子名称: | De novo designed homotetramer | | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Oberdorfer, G, Boyken, S.E, Chen, Z. | | 登録日 | 2016-05-05 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.83 Å) | | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
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5F72
 | | De novo design and crystallographic validation of antibodies targeting a pre-selected epitope | | 分子名称: | Kelch-like ECH-associated protein 1, Single chain Fv from a Fab | | 著者 | Liu, X, Taylor, R.D, Griffin, L, Coker, S, Adams, R, Ceska, T, Shi, J, Lawson, A.D.G, Baker, T. | | 登録日 | 2015-12-07 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | De novo design and crystallographic validation of antibodies targeting a pre-selected epitope
To Be Published
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6S3D
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6E9R
 | | DHF46 filament | | 分子名称: | DHF46 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9Z
 | | DHF119 filament | | 分子名称: | DHF119 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9V
 | | DHF79 filament | | 分子名称: | DHF79 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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7UPQ
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7UPP
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7UPO
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1Y4C
 | | Designed Helical Protein fusion MBP | | 分子名称: | Maltose binding protein fused with designed helical protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | LaPorte, S.L, Forsyth, C.M, Cunningham, B.C, Miercke, L.J, Akhavan, D, Stroud, R.M. | | 登録日 | 2004-11-30 | | 公開日 | 2005-02-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | De novo design of an IL-4 antagonist and its structure at 1.9 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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6MSQ
 | | Crystal structure of pRO-2.3 | | 分子名称: | pRO-2.3 | | 著者 | Boyken, S.E, Sankaran, B, Bick, M.J, Baker, D. | | 登録日 | 2018-10-17 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
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6MSR
 | | Crystal structure of pRO-2.5 | | 分子名称: | pRO-2.5 | | 著者 | Bick, M.J, Sankaran, B, Boyken, S.E, Baker, D. | | 登録日 | 2018-10-17 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
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7UDK
 | | Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide | | 分子名称: | 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4 | | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-03-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
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7UDO
 | | Crystal structure of designed helical repeat protein RPB_LRP2_R4 (proteolysis fragment?), forming pseudopolymeric filaments | | 分子名称: | 1,2-ETHANEDIOL, Designed helical repeat protein (DHR) RPB_LRP2_R4, PHOSPHATE ION | | 著者 | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-03-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
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7UDL
 | | Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide | | 分子名称: | 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6 | | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-03-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
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7UDN
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7UDM
 | | Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide) | | 分子名称: | 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6 | | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-03-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
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