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PDB: 417 件
8B0X
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BU of 8b0x by Molmil
Translating 70S ribosome in the unrotated state (P and E, tRNAs)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S.
登録日2022-09-08
公開日2022-11-30
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.55 Å)
主引用文献The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services.
Nat Commun, 14, 2023
8CF1
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Tetracycline bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
登録日2023-02-02
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.82 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8FTO
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BU of 8fto by Molmil
E. coli 70S ribosome with an improved MS2 tag inserted in H98
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nissley, A.J, Cate, J.H.D.
登録日2023-01-12
公開日2023-08-02
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.85 Å)
主引用文献Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
8CGI
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BU of 8cgi by Molmil
Pentacycline TP038 bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S7, Large ribosomal subunit protein bL31A, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-02-04
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.89 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8AYE
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BU of 8aye by Molmil
E. coli 70S ribosome bound to thermorubin and fMet-tRNA
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Sanyal, S, Parajuli, N.P, Emmerich, A.G.
登録日2022-09-02
公開日2023-03-01
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (1.96 Å)
主引用文献Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.
Nat Commun, 14, 2023
7K00
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Structure of the Bacterial Ribosome at 2 Angstrom Resolution
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Watson, Z.L, Ward, F.R, Meheust, R, Ad, O, Schepartz, A, Banfield, J.F, Cate, J.H.D.
登録日2020-09-02
公開日2020-09-23
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structure of the bacterial ribosome at 2 angstrom resolution.
Elife, 9, 2020
8QOA
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BU of 8qoa by Molmil
Structure of SecM-stalled Escherichia coli 70S ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
著者Gersteuer, F, Morici, M, Wilson, D.N.
登録日2023-09-28
公開日2024-03-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome.
Nat Commun, 15, 2024
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
分子名称: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-04-05
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.02 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8BIM
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BU of 8bim by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAm6A codon in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-11-02
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BIL
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BU of 8bil by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAA codon in the A-site.
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-11-02
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8CA7
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BU of 8ca7 by Molmil
Omadacycline and spectinomycin bound to the 30S ribosomal subunit head
分子名称: 16S rRNA, 30S ribosomal protein S7, MAGNESIUM ION, ...
著者Paternoga, H, Crowe-McAuliffe, C, Wilson, D.N.
登録日2023-01-24
公開日2023-08-02
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.06 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
4YBB
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BU of 4ybb by Molmil
High-resolution structure of the Escherichia coli ribosome
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D.
登録日2015-02-18
公開日2015-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
8EMM
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BU of 8emm by Molmil
Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Watson, Z.L, Cate, J.H.D.
登録日2022-09-28
公開日2023-05-31
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
8CAZ
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BU of 8caz by Molmil
empty 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Beckert, B, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8BGE
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BU of 8bge by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and AAm6A mRNA codon in the A-site after uncompleted di-peptide formation
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8CF8
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BU of 8cf8 by Molmil
Eravacycline bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-03
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8R6C
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BU of 8r6c by Molmil
70S Escherichia coli ribosome with Paenilamicin B2 bound with A- and P-site tRNA.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
著者Koller, T.O, Wilson, D.N.
登録日2023-11-22
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
8QBT
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BU of 8qbt by Molmil
E. coli ApdP-stalled ribosomal complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
著者Morici, M, Wilson, D.N.
登録日2023-08-25
公開日2024-03-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
8BHL
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BU of 8bhl by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and Am6AA mRNA codon in the A-site after uncompleted di-peptide formation
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-31
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.21 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8EIU
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BU of 8eiu by Molmil
E. coli 70S ribosome with A-loop mutations U2554C and U2555C
分子名称: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
登録日2022-09-15
公開日2023-02-01
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
8YUO
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BU of 8yuo by Molmil
E. coli 70S ribosome complexed with P. putida tRNAIle2 at the A-site and P-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Akiyama, N, Ishiguro, K, Shirouzu, M, Suzuki, T.
登録日2024-03-27
公開日2024-11-06
実験手法ELECTRON MICROSCOPY (2.25 Å)
主引用文献A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis.
Nat.Chem.Biol., 2024
8AKN
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BU of 8akn by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome
分子名称: 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ...
著者Koller, T.O, Morici, M, Wilson, D.N.
登録日2022-07-30
公開日2023-03-08
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
8HSP
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BU of 8hsp by Molmil
E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-12-20
公開日2024-04-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.32 Å)
主引用文献Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine.
Nat.Struct.Mol.Biol., 31, 2024
7N1P
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Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, S.K, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C.
登録日2021-05-28
公開日2021-07-14
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
8BF7
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Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and AAA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-24
公開日2023-08-16
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023

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