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PDB: 276 件

3RDQ
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Crystal structure of R7-2 streptavidin complexed with desthiobiotin
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GLYCEROL, NICKEL (II) ION, ...
著者Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C.
登録日2011-04-01
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
Protein Sci., 20, 2011
1N9M
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Streptavidin Mutant S27A with Biotin at 1.6A Resolution
分子名称: BIOTIN, Streptavidin
著者Le Trong, I, Freitag, S, Klumb, L.A, Chu, V, Stayton, P.S, Stenkamp, R.E.
登録日2002-11-25
公開日2003-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin.
Acta Crystallogr.,Sect.D, 59, 2003
6AUH
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Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112Y-a
分子名称: N-biotin-C-Co4(mu3-O)4(OAc)(Py)3(H2O)3-beta-alanine, Streptavidin
著者Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S.
登録日2017-09-01
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
8QQ3
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Streptavidin with a Ni-cofactor
分子名称: 4-[4-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butylamino]-~{N}1,~{N}1'-di(quinolin-8-yl)cyclohexane-1,1-dicarboxamide, NICKEL (II) ION, Streptavidin
著者Zhang, K, Jakob, R.P, Ward, T.R.
登録日2023-10-03
公開日2024-02-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献An artificial nickel chlorinase based on the biotin-streptavidin technology.
Chem.Commun.(Camb.), 60, 2024
6GMI
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Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in E. coli's Periplasm.
分子名称: IRIDIUM (III) ION, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III)
著者Rebelein, J.G.
登録日2018-05-26
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli's Periplasm.
J. Am. Chem. Soc., 140, 2018
3RDM
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BU of 3rdm by Molmil
Crystal structure of R7-2 streptavidin complexed with biotin/PEG
分子名称: BIOTIN, PENTAETHYLENE GLYCOL, Streptavidin
著者Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C.
登録日2011-04-01
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.
Protein Sci., 20, 2011
5N8T
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CRYSTAL STRUCTURE OF STREPTAVIDIN D-amino acid containing peptide Gdlwqheatwkkq
分子名称: DLE-DTR-DGN-DHI-DGL-DAL-DTH-DTR-DLY, Streptavidin
著者Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J.
登録日2017-02-24
公開日2017-10-04
最終更新日2022-12-07
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target.
Sci Rep, 7, 2017
2RTR
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STREPTAVIDIN-2-IMINOBIOTIN COMPLEX, PH 4.0, SPACE GROUP I222
分子名称: 2-IMINOBIOTIN, STREPTAVIDIN
著者Katz, B.A.
登録日1997-09-11
公開日1998-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
6ANX
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Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins - WT (low exposure)
分子名称: ACETATE ION, SULFATE ION, Streptavidin, ...
著者Mann, S.I, Heinisch, T, Ward, T.R, Borovik, A.S.
登録日2017-08-14
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins.
J. Am. Chem. Soc., 139, 2017
6FH8
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E. coli surface display of streptavidin for directed evolution of an allylic deallocase
分子名称: Streptavidin, biotinylated ruthenium cyclopentadienide
著者Heinisch, T, Schwizer, F, Garabedian, B, Csibra, E, Jeschek, M, Pinheiro Bernhardes, V, Marliere, P, Panke, S, Ward, T.R.
登録日2018-01-12
公開日2018-08-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献E. colisurface display of streptavidin for directed evolution of an allylic deallylase.
Chem Sci, 9, 2018
4CPH
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trans-divalent streptavidin with love-hate ligand 4
分子名称: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide, STREPTAVIDIN
著者Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M.
登録日2014-02-06
公開日2014-08-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22, 2014
1VWO
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STREPTAVIDIN COMPLEXED WITH CYCLO-AC-[CHPQGPPC]-NH2 MONOMER, PH 2.85
分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1SRI
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
分子名称: 2-((3',5'-DIMETHYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID, STREPTAVIDIN
著者Weber, P.C, Salemme, F.R.
登録日1994-02-17
公開日1994-11-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1MEP
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BU of 1mep by Molmil
Crystal Structure of Streptavidin Double Mutant S45A/D128A with Biotin: Cooperative Hydrogen-Bond Interactions in the Streptavidin-Biotin System.
分子名称: BIOTIN, Streptavidin
著者Hyre, D.E, Le Trong, I, Merritt, E.A, Stenkamp, R.E, Green, N.M, Stayton, P.S.
登録日2002-08-08
公開日2003-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
2RTD
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STREPTAVIDIN-BIOTIN COMPLEX, PH 1.39, SPACE GROUP I222
分子名称: BIOTIN, STREPTAVIDIN
著者Katz, B.A.
登録日1997-09-11
公開日1998-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
6VP3
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Artificial Metalloproteins with Dinuclear Iron Centers
分子名称: ACETATE ION, Streptavidin, {N-(4-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}butyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+)
著者Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S.
登録日2020-02-01
公開日2021-02-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
5TO2
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Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
分子名称: DI(HYDROXYETHYL)ETHER, Streptavidin
著者Zhang, M, Biswas, S, Deng, W, Yu, H.
登録日2016-10-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
To Be Published
8AQY
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streptavidin mutant S112A with an iridium catalyst for CH activation
分子名称: Streptavidin, tert-butyl 7'-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-1-chloranyl-2,3,4,5,6-pentamethyl-spiro[1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane-1,2'-3-aza-1-azonia-2$l^{8}-iridatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene]-3'-carboxylate
著者Igareta, N.V, Ward, T.R.
登録日2022-08-15
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献streptavidin mutant S112A with an iridium catalyst for CH activation
To Be Published
2QCB
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T7-tagged full-length streptavidin complexed with ruthenium ligand
分子名称: N-(4-{[(2-AMINOETHYL)AMINO]SULFONYL}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE-(1,2,3,4,5,6-ETA)-BENZENE-CHLORO-RUTHENIUM(III), Streptavidin
著者Le Trong, I, Creus, M, Pordea, A, Ward, T.R, Stenkamp, R.E.
登録日2007-06-19
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献X-ray structure and designed evolution of an artificial transfer hydrogenase
Angew.Chem.Int.Ed.Engl., 47, 2008
1MM9
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Streptavidin Mutant with Insertion of Fibronectin Hexapeptide, including RGD
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Streptavidin
著者Le Trong, I, McDevitt, T.C, Nelson, K.E, Stayton, P.S, Stenkamp, R.E.
登録日2002-09-03
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin.
Acta Crystallogr.,Sect.D, 59, 2003
1VWQ
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STREPTAVIDIN-CYCLO-[5-S-VALERAMIDE-HPQGPPC]K-NH2, PH 2.5, I4122 COMPLEX
分子名称: PENTANOIC ACID, PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
5VL8
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Coordination Chemistry within a Protein Host: Regulation of the Secondary Coordination Sphere
分子名称: COPPER (II) ION, GLYCEROL, Streptavidin, ...
著者Mann, S.I, Heinisch, T, Ward, T.R, Borovik, A.S.
登録日2017-04-25
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Coordination chemistry within a protein host: regulation of the secondary coordination sphere.
Chem. Commun. (Camb.), 54, 2018
1NBX
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Streptavidin Mutant Y43A at 1.70A Resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Streptavidin
著者Le Trong, I, Freitag, S, Klumb, L.A, Chu, V, Stayton, P.S, Stenkamp, R.E.
登録日2002-12-04
公開日2003-09-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin.
Acta Crystallogr.,Sect.D, 59, 2003
6QSY
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Engineered streptavidin variant (H--WY) in complex with the Strep-tag II peptide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Strep-tag II peptide, Streptavidin, ...
著者Skerra, A, Eichinger, A.
登録日2019-02-22
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
5L3Y
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Designed Artificial Cupredoxins
分子名称: Streptavidin, [CuII(biot-et-dpea)]2+
著者Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S.
登録日2016-05-24
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modular Artificial Cupredoxins.
J.Am.Chem.Soc., 138, 2016

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