2X4U
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![BU of 2x4u by Molmil](/molmil-images/mine/2x4u) | Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 Peptide RT468-476 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ... | 著者 | Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. | 登録日 | 2010-02-02 | 公開日 | 2010-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals. J.Am.Chem.Soc., 131, 2009
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5EUO
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![BU of 5euo by Molmil](/molmil-images/mine/5euo) | PF6-M1-HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Yang, X. | 登録日 | 2015-11-18 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of PF6-M1-HLA-A2 complex To Be Published
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3GSX
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![BU of 3gsx by Molmil](/molmil-images/mine/3gsx) | Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8V peptide variant | 分子名称: | Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8V (NLVPMVAVV), ... | 著者 | Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
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2F53
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![BU of 2f53 by Molmil](/molmil-images/mine/2f53) | Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ... | 著者 | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | 登録日 | 2005-11-25 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Protein Sci., 15, 2006
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4NO5
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![BU of 4no5 by Molmil](/molmil-images/mine/4no5) | Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2 | 分子名称: | 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ... | 著者 | Mohammed, F, Stones, D.H, Willcox, B.E. | 登録日 | 2013-11-19 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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4NNX
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![BU of 4nnx by Molmil](/molmil-images/mine/4nnx) | Crystal structure of PKD2 phosphopeptide bound to HLA-A2 | 分子名称: | Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ... | 著者 | Mohammed, F, Stones, D.H, Willcox, B.E. | 登録日 | 2013-11-19 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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6SSA
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![BU of 6ssa by Molmil](/molmil-images/mine/6ssa) | |
5C07
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![BU of 5c07 by Molmil](/molmil-images/mine/5c07) | 1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA | 分子名称: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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4JFO
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![BU of 4jfo by Molmil](/molmil-images/mine/4jfo) | A2 HLA complex with E1A heteroclitic variant of Melanoma peptide | 分子名称: | Beta-2-microglobulin, E1A heteroclitic Melanoma peptide, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K, Baker, B.M. | 登録日 | 2013-02-28 | 公開日 | 2013-05-29 | 最終更新日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
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3GSQ
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![BU of 3gsq by Molmil](/molmil-images/mine/3gsq) | Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5S peptide variant | 分子名称: | Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5S (NLVPSVATV), ... | 著者 | Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
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7RRG
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![BU of 7rrg by Molmil](/molmil-images/mine/7rrg) | |
5EU4
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![BU of 5eu4 by Molmil](/molmil-images/mine/5eu4) | HLA Class I antigen | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | 登録日 | 2015-11-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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1W72
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![BU of 1w72 by Molmil](/molmil-images/mine/1w72) | Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3 | 分子名称: | BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A. | 登録日 | 2004-08-27 | 公開日 | 2004-11-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3 J.Biol.Chem., 280, 2005
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1DUY
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![BU of 1duy by Molmil](/molmil-images/mine/1duy) | CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX | 分子名称: | BETA-2 MICROGLOBULIN, HLA-A2*0201, HTLV-1 OCTAMERIC TAX PEPTIDE | 著者 | Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C. | 登録日 | 2000-01-19 | 公開日 | 2000-02-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site. J.Immunol., 164, 2000
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6PTB
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![BU of 6ptb by Molmil](/molmil-images/mine/6ptb) | Crystal Structure of ILNAMIAKI peptide bound to HLA-A2 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ... | 著者 | Keller, G.L.J, Arbuiso, A, Baker, B.M. | 登録日 | 2019-07-15 | 公開日 | 2019-09-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure Based Prediction of Neoantigen Immunogenicity. Front Immunol, 10, 2019
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1JHT
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![BU of 1jht by Molmil](/molmil-images/mine/1jht) | Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (ALGIGILTV) from the MART-1/Melan-A. | 分子名称: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, beta-2-microglobulin, ... | 著者 | Sliz, P, Michielin, O, Karplus, M, Romero, P, Wiley, D. | 登録日 | 2001-06-28 | 公開日 | 2001-09-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes. J.Immunol., 167, 2001
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6AMU
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![BU of 6amu by Molmil](/molmil-images/mine/6amu) | |
1T21
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![BU of 1t21 by Molmil](/molmil-images/mine/1t21) | Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, monoclinic crystal | 分子名称: | Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ... | 著者 | Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y. | 登録日 | 2004-04-19 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281, 2006
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3MGT
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![BU of 3mgt by Molmil](/molmil-images/mine/3mgt) | Crystal structure of a H5-specific CTL epitope variant derived from H5N1 influenza virus in complex with HLA-A*0201 | 分子名称: | 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y. | 登録日 | 2010-04-07 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses J.Gen.Virol., 91, 2010
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5HGA
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![BU of 5hga by Molmil](/molmil-images/mine/5hga) | HLA*A2402 complex with HIV nef138 Y2F-8mer mutant epitope | 分子名称: | 8-mer from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2016-01-08 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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4OV5
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![BU of 4ov5 by Molmil](/molmil-images/mine/4ov5) | Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket | 分子名称: | HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ... | 著者 | Trenh, P, Yin, L, Stern, L.J. | 登録日 | 2014-02-20 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289, 2014
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6O9B
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![BU of 6o9b by Molmil](/molmil-images/mine/6o9b) | |
7MLE
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![BU of 7mle by Molmil](/molmil-images/mine/7mle) | Crystal Structure of HLA-A*03:01 in complex with VVRPSVASK, an 9-mer epitope from Influenza B virus | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | 著者 | Gras, S, Nguyen, A.T, Szeto, C. | 登録日 | 2021-04-28 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Homologous peptides derived from influenza A, B and C viruses induce variable CD8 + T cell responses with cross-reactive potential. Clin Transl Immunology, 11, 2022
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1IM3
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![BU of 1im3 by Molmil](/molmil-images/mine/1im3) | Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax | 分子名称: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, Human T-cell lymphotropic virus type 1 Tax peptide, ... | 著者 | Gewurz, B.E, Gaudet, R, Tortorella, D, Wang, E.W, Ploegh, H.L, Wiley, D.C. | 登録日 | 2001-05-09 | 公開日 | 2001-06-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proc.Natl.Acad.Sci.USA, 98, 2001
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3MRQ
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![BU of 3mrq by Molmil](/molmil-images/mine/3mrq) | Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant | 分子名称: | 10-meric peptide from Melanoma antigen recognized by T-cells 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant To be Published
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