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PDB: 377 件
2BNQ
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
著者Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
登録日2005-03-31
公開日2005-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
5TEZ
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BU of 5tez by Molmil
TCR F50 recgonizing M1-HLA-A2
分子名称: Beta-2-microglobulin, GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU, HLA class I histocompatibility antigen, ...
著者Yang, X, Mariuzza, R.A.
登録日2016-09-23
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope.
J. Biol. Chem., 292, 2017
2GTZ
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BU of 2gtz by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-28
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
3MRD
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BU of 3mrd by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide V6G variant
分子名称: 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Gras, S, Reiser, J.-B, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
3PWJ
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BU of 3pwj by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
2GIT
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BU of 2git by Molmil
Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
分子名称: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-03-29
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
3BH9
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BU of 3bh9 by Molmil
Crystal Structure of RTY Phosphopeptide Bound to Human Class I MHC HLA-A2
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E.
登録日2007-11-28
公開日2008-10-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9, 2008
3O3D
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BU of 3o3d by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
4NO3
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BU of 4no3 by Molmil
Crystal structure of AMPD2 phosphopeptide bound to HLA-A2
分子名称: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ...
著者Mohammed, F, Stones, D.H, Willcox, B.E.
登録日2013-11-19
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
5N6B
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BU of 5n6b by Molmil
Human Leukocyte Antigen Class I A02 Carrying LLWNPGMAV
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Bulek, A.M, Bovay, A.
登録日2017-02-14
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus.
Eur. J. Immunol., 48, 2018
2GT9
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BU of 2gt9 by Molmil
Human Class I MHC HLA-A2 in complex with the decameric Melan-A/MART-1(26-35) peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-27
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
4I4W
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BU of 4i4w by Molmil
Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Wooldridge, L, Cole, D.K.
登録日2012-11-28
公開日2013-01-02
最終更新日2015-11-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
5MEO
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BU of 5meo by Molmil
Human Leukocyte Antigen presenting ILGKFLHRL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
6OPD
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BU of 6opd by Molmil
Crystal Structure of ILNAMIVKI peptide bound to HLA-A2
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Davancaze, L.M, Arbuiso, A, Baker, B.M.
登録日2019-04-24
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
3FQU
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BU of 3fqu by Molmil
Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Petersen, J, Rossjohn, J.
登録日2009-01-07
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes
Proc.Natl.Acad.Sci.Usa, 106, 2009
3FT2
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BU of 3ft2 by Molmil
Crystal Structure of a citrulline peptide variant of the minor histocompatibility peptide HA-1 in complex with HLA-A2
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Reiser, J.-B, Gras, S, Chouquet, A, Le Gorrec, M, Spierings, E, Goulmy, E, Housset, D.
登録日2009-01-12
公開日2009-04-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele.
J.Immunol., 182, 2009
3FQT
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BU of 3fqt by Molmil
Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Petersen, J, Rossjohn, J.
登録日2009-01-07
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes
Proc.Natl.Acad.Sci.Usa, 106, 2009
3VXS
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BU of 3vxs by Molmil
The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(6L) peptide
分子名称: 10-mer peptide from Protein Nef, Beta-2-microglobulin, H27-14 TCR alpha chain, ...
著者Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
登録日2012-09-20
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
1DUZ
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BU of 1duz by Molmil
HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) IN COMPLEX WITH A NONAMERIC PEPTIDE FROM HTLV-1 TAX PROTEIN
分子名称: BETA-2 MICROGLOBULIN, HLA-A*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
著者Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
登録日2000-01-19
公開日2000-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
3BO8
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BU of 3bo8 by Molmil
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2007-12-17
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity
Protein Sci., 18, 2009
5GRD
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BU of 5grd by Molmil
Crystal structure of 10-mer peptide from EBV in complex with HLA-A1101.
分子名称: Beta-2-microglobulin, Epstein Barr Virus, Latent membrane protein 2 epitope, ...
著者Tadwal, V.S, Xiao, Z, Ren, E.C.
登録日2016-08-10
公開日2017-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Sci Rep, 7, 2017
3MRC
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BU of 3mrc by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide V6C variant
分子名称: 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Gras, S, Reiser, J.-B, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
1I7U
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BU of 1i7u by Molmil
CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-6V
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
J.Biol.Chem., 276, 2001
3GSU
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BU of 3gsu by Molmil
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5T peptide variant
分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5T (NLVPTVATV), ...
著者Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
登録日2009-03-27
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009
3O3A
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BU of 3o3a by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010

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