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PDB: 4 件
6MVL
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BU of 6mvl by Molmil
Crystal structure of VISTA bound to a pH-selective antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, ...
著者Critton, D.A.
登録日2018-10-26
公開日2019-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献VISTA is an acidic pH-selective ligand for PSGL-1.
Nature, 574, 2019
6OIL
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BU of 6oil by Molmil
Crystal structure of human VISTA extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation
著者Mehta, N, Cochran, J.R, Mathews, I.I.
登録日2019-04-09
公開日2019-09-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation.
Cell Rep, 28, 2019
6U6V
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BU of 6u6v by Molmil
Crystal structure of human PD-1H / VISTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation
著者Slater, B.T, Han, X, Chen, L, Xiong, Y.
登録日2019-08-30
公開日2020-01-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into T cell coinhibition by PD-1H (VISTA).
Proc.Natl.Acad.Sci.USA, 117, 2020
8TBQ
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The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of pH-selective anti-VISTA antibody
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SNS-101 Fab heavy chain, ...
著者van der Horst, E.H, Mukherjee, A, Thisted, T.
登録日2023-06-29
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.593 Å)
主引用文献The pH-selective anti-VISTA antibody SNS-101 displays a favorable pharmacokinetic and safety profile and promotes anti-tumoral M1 macrophage polarization in PD-1 refractory settings
To Be Published

222415

件を2024-07-10に公開中

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