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PDB: 19 件
7SNS
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1.55A Resolution Structure of NanoLuc Luciferase
分子名称: ACETATE ION, Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献1.55A Resolution Structure of NanoLuc Luciferase
To be published
8AQ6
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NanoLuc luciferase with bound furimamide in surface allosteric site
分子名称: CHLORIDE ION, GLYCEROL, N-(3-Benzyl-5-phenylpyrazin-2-yl)-2-(furan-2-yl)acetamide, ...
著者Nemergut, M, Marek, M.
登録日2022-08-11
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
7VSX
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Crystal structure of QL-nanoKAZ (Reverse mutant of nanoKAZ with L18Q and V27L)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, QLnK
著者Tomabechi, Y, Sekine, S, Shirouzu, M, Takamitsu, H, Satoshi, I.
登録日2021-10-27
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate.
Plos One, 17, 2022
7SNX
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1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits
分子名称: GLYCEROL, Oplophorus-luciferin 2-monooxygenase catalytic subunit, Oplophorus-luciferin 2-monooxygenase catalytic subunit: C-terminal Peptide (11-mer)
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits
To be published
5B0U
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Crystal structure of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ)
分子名称: Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Tomabechi, Y, Ehara, H, Sekine, S.I, Shirouzu, M.
登録日2015-11-04
公開日2016-01-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine
Biochem.Biophys.Res.Commun., 470, 2016
7SNW
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1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576
分子名称: 2-(methoxycarbonyl)thiophene-3-sulfonic acid, CHLORIDE ION, GLYCEROL, ...
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576
To be published
5IBO
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1.95A resolution structure of NanoLuc luciferase
分子名称: DECANOIC ACID, Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2016-02-22
公開日2016-04-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献To be determined
To be published
8AQI
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NanoLuc luciferase with bound coelenteramide in surface allosteric site
分子名称: CHLORIDE ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, NanoLuc luciferase, ...
著者Nemergut, M, Marek, M.
登録日2022-08-12
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
7SNR
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2.00A Resolution Structure of NanoLuc Luciferase
分子名称: ACETATE ION, CITRATE ANION, Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2.00A Resolution Structure of NanoLuc Luciferase
To be published
7SNY
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2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT
分子名称: Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT
To be published
7SNT
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2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine
分子名称: (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine, Oplophorus-luciferin 2-monooxygenase catalytic subunit
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Unch, J, Encell, L.P, Wood, K.V.
登録日2021-10-28
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine
To be published
8AQH
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NanoLuc-Y94A luciferase mutant
分子名称: NanoLuc luciferase
著者Nemergut, M, Marek, M.
登録日2022-08-12
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
8JPN
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Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
分子名称: (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y.
登録日2023-06-12
公開日2024-05-22
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
Cell Res., 34, 2024
8HNM
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CXCR3-DNGi complex activated by VUF11222
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Jiao, H.Z, Hu, H.L.
登録日2022-12-08
公開日2023-11-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
8HNL
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CXCR3-DNGi complex activated by PS372424
分子名称: (3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Jiao, H.Z, Hu, H.L.
登録日2022-12-08
公開日2023-11-29
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
8HCQ
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Cryo-EM structure of endothelin1-bound ETAR-Gq complex
分子名称: Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J.
登録日2022-11-02
公開日2023-03-22
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
8HNK
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CXCR3-DNGi complex activated by CXCL11
分子名称: C-X-C motif chemokine 11, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Jiao, H.Z, Hu, H.L.
登録日2022-12-08
公開日2023-11-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
8K2X
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CXCR3-DNGi complex activated by CXCL10
分子名称: C-X-C motif chemokine 10, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Jiao, H.Z, Hu, H.L.
登録日2023-07-14
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487.
Cell Discov, 9, 2023
8HCX
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Cryo-EM structure of Endothelin1-bound ETBR-Gq complex
分子名称: Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J.
登録日2022-11-03
公開日2023-03-22
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023

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件を2024-10-09に公開中

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