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PDB: 11 件

3DVO
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BU of 3dvo by Molmil
SgrAI with cognate DNA and calcium bound
分子名称: CALCIUM ION, DNA (5'-D(*DGP*DAP*DGP*DTP*DCP*DCP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DTP*DC)-3'), SgraIR restriction enzyme
著者Dunten, P.W, Horton, N.C, Little, E.J.
登録日2008-07-18
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献The structure of SgrAI bound to DNA; recognition of an 8 base pair target.
Nucleic Acids Res., 36, 2008
3DPG
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BU of 3dpg by Molmil
SgrAI with noncognate DNA bound
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DAP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DT)-3'), SgraIR restriction enzyme
著者Dunten, P.W, Horton, N.C, Little, E.J.
登録日2008-07-08
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The structure of SgrAI bound to DNA; recognition of an 8 base pair target.
Nucleic Acids Res., 36, 2008
3MQY
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BU of 3mqy by Molmil
SgrAI with cleaved DNA and Magnesium bound
分子名称: DNA (5'-D(*GP*AP*GP*TP*CP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*GP*TP*GP*GP*AP*CP*TP*C)-3'), MAGNESIUM ION, ...
著者Dunten, P.W, Horton, N.C, Little, E.J.
登録日2010-04-28
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.
Acta Crystallogr.,Sect.D, 67, 2011
3MQ6
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BU of 3mq6 by Molmil
Domain swapped SgrAI with DNA and calcium bound
分子名称: CALCIUM ION, DNA (5'-D(*AP*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), SgraIR restriction enzyme
著者Dunten, P.W, Horton, N.C, Little, E.J.
登録日2010-04-27
公開日2010-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Domain swapping in allosteric modulation of DNA specificity.
Plos Biol., 8, 2010
7S8D
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BU of 7s8d by Molmil
Structure of DNA-free SgrAI
分子名称: CALCIUM ION, SgraIR restriction enzyme
著者Horton, N.C.
登録日2021-09-17
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
J.Biol.Chem., 298, 2022
3DW9
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BU of 3dw9 by Molmil
SgrAI with cognate DNA and manganese bound
分子名称: DNA (5'-D(*DGP*DAP*DGP*DTP*DCP*DCP*DAP*DCP*DCP*DGP*DGP*DTP*DGP*DGP*DAP*DCP*DTP*DC)-3'), MANGANESE (II) ION, SgraIR restriction enzyme
著者Dunten, P.W, Horton, N.C, Little, E.J.
登録日2008-07-21
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of SgrAI bound to DNA; recognition of an 8 base pair target.
Nucleic Acids Res., 36, 2008
3N7B
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BU of 3n7b by Molmil
SgrAI bound to secondary site DNA and Ca(II)
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), ...
著者Horton, N.C, Little, E.J, Dunten, P.W.
登録日2010-05-26
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.
Acta Crystallogr.,Sect.D, 67, 2011
7SS5
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BU of 7ss5 by Molmil
Activated SgrAI endonuclease DNA-bound dimer with Ca2+ and intact primary site DNA
分子名称: CALCIUM ION, DNA (5'-D(P*GP*GP*TP*CP*TP*TP*CP*AP*CP*AP*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*C)-3'), SgraIR restriction enzyme
著者Shan, Z, Lyumkis, D, Horton, N.C.
登録日2021-11-09
公開日2021-12-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
J.Biol.Chem., 298, 2022
3N78
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BU of 3n78 by Molmil
SgrAI bound to Secondary Site DNA and Mg(II)
分子名称: DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), MAGNESIUM ION, ...
著者Horton, N.C, Little, E.J, Dunten, P.W.
登録日2010-05-26
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.
Acta Crystallogr.,Sect.D, 67, 2011
6OBJ
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BU of 6obj by Molmil
Structure of a DNA-bound dimer extracted from filamentous SgrAI endonuclease in its activated form
分子名称: DNA (26-MER), MAGNESIUM ION, SgraIR restriction enzyme
著者Polley, S, Lyumkis, D, Horton, N.C.
登録日2019-03-20
公開日2020-02-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease.
Structure, 27, 2019
4C3G
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BU of 4c3g by Molmil
cryo-EM structure of activated and oligomeric restriction endonuclease SgrAI
分子名称: 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3', 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', SGRAIR RESTRICTION ENZYME
著者Lyumkis, D, Talley, H, Stewart, A, Shah, S, Park, C.K, Tama, F, Potter, C.S, Carragher, B, Horton, N.C.
登録日2013-08-23
公開日2013-09-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.
Structure, 21, 2013

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件を2024-07-17に公開中

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