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PDB: 12 件

8JZX
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SLC15A4 inhibitor complex
分子名称: 2-(4-ethoxyphenyl)-N-[3-[(2R)-2-methylpiperidin-1-yl]propyl]quinoline-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity.
Nat Commun, 14, 2023
8QSL
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Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
登録日2023-10-10
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
To Be Published
8WX3
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Cryo-EM structure of human SLC15A4 (outward-facing open)
分子名称: Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Cryo-EM structure of human SLC15A4 (outward-facing open)
To Be Published
8JZS
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Outward-facing SLC15A4 dimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
8JZU
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BU of 8jzu by Molmil
SLC15A4_TASL complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
8WX4
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Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
分子名称: LEUCINE, LYSINE, Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
To Be Published
8JZR
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BU of 8jzr by Molmil
Outward_facing SLC15A4 monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
8QSK
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BU of 8qsk by Molmil
Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
登録日2023-10-10
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of human SLC15A4 dimer in outward open state in MSP1D1 nanodisc
To Be Published
8QSN
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Cryo-EM structure of human SLC15A4 monomer in outward open state in PMAL C8
分子名称: Solute carrier family 15 member 4
著者Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
登録日2023-10-10
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Cryo-EM structure of human SLC15A4 monomer in outward open state in PMAL C8
To Be Published
8P6A
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BU of 8p6a by Molmil
cryo-EM structure of human SLC15A4 in outward-open state
分子名称: Solute carrier family 15 member 4
著者Parker, J.L, Kato, T, Newstead, S.
登録日2023-05-25
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献cryo-EM structure of human SLC15A4 PHT1 in outward-open state
To be published
8QSM
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BU of 8qsm by Molmil
Cryo-EM structure of human SLC15A4 monomer in outward open state in LMNG
分子名称: Solute carrier family 15 member 4
著者Rehan, S, Matsuoka, R, Jazayeri, A, Duerr, K.L.
登録日2023-10-10
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Cryo-EM structure of human SLC15A4 monomer in outward open state in LMNG
To Be Published
8WX5
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BU of 8wx5 by Molmil
Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
分子名称: Solute carrier family 15 member 4, TASL (TASL-SLC15A4 fusion protein)
著者Ohto, U, Zhang, Z, Fujimura, A, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
To Be Published

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件を2024-07-10に公開中

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