4CA1
| Crystal structure of Siah1 at 1.58 A resolution. | 分子名称: | CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE SIAH1, GLYCEROL, ... | 著者 | Rimsa, V, Eadsforth, T.C, Hunter, W.N. | 登録日 | 2013-10-04 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Two High-Resolution Structures of the Human E3 Ubiquitin Ligase Siah1. Acta Crystallogr.,Sect.F, 96, 2013
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4C9Z
| Crystal structure of Siah1 at 1.95 A resolution | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE SIAH1, ... | 著者 | Rimsa, V, Eadsforth, T.C, Hunter, W.N. | 登録日 | 2013-10-04 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Two High-Resolution Structures of the Human E3 Ubiquitin Ligase Siah1. Acta Crystallogr.,Sect.F, 96, 2013
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5WZZ
| The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation | 分子名称: | Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION | 著者 | Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. | 登録日 | 2017-01-19 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation Genes Dev., 31, 2017
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2A25
| Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP | 分子名称: | Calcyclin-binding protein peptide, Ubiquitin ligase SIAH1, ZINC ION | 著者 | Santelli, E, Leone, M, Li, C, Fukushima, T, Preece, N.E, Olson, A.J, Ely, K.R, Reed, J.C, Pellecchia, M, Liddington, R.C, Matsuzawa, S. | 登録日 | 2005-06-21 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex J.Biol.Chem., 280, 2005
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4X3G
| Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide | 分子名称: | E3 ubiquitin-protein ligase SIAH1, Ubiquitin carboxyl-terminal hydrolase 19, ZINC ION | 著者 | Walker, J.R, Dong, A, Zhang, Q, Huang, X, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2014-11-28 | 公開日 | 2014-12-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide To be published
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4I7D
| Siah1 bound to synthetic peptide (ACE)KLRPVAMVRP(PRK)VR | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
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8HEO
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4I7C
| Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ... | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
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4I7B
| Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR | 分子名称: | E3 ubiquitin-protein ligase SIAH1, Protein phyllopod, ZINC ION | 著者 | Santelli, E, Stebbins, J.L, Feng, Y, De, S.K, Purves, A, Motamedchaboki, K, Wu, B, Ronai, Z.A, Liddington, R.C, Pellecchia, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based design of covalent siah inhibitors. Chem.Biol., 20, 2013
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